Serum aspirin esterase is strongly associated with glucose and lipids in healthy subjects: different association patterns in subjects with type 2 diabetes mellitus

<p>Abstract</p> <p>Background</p> <p>Aspirin esterase (AE) activity can account for part of aspirin pharmacokinetics in the circulation, possibly being associated with the impairment of aspirin effectiveness as an inhibitor of platelet aggregation.</p> <p>Aims</p> <p>The study was aimed at investigating the correlations of serum AE activity with cholinesterase (ChE) and metabolic variables in healthy subjects in comparison to subjects with type 2 diabetes mellitus (T2DM).</p> <p>Methods</p> <p>In cardiovascular disease-free T2DM subjects and healthy controls, the AE activity levels and/or the correlation patterns between AE and the other variables were analyzed.</p> <p>Results</p> <p>Neither AE nor ChE activities were higher in the subjects with T2DM. Serum AE activity strongly correlated with ChE as well as glucose/lipids variables such as total cholesterol and triglyceride in healthy subjects, while the correlations between AE and glucose/lipids variables were not present in T2DM subjects.</p> <p>Conclusions</p> <p>These data may reflect the pathophysiological changes between healthy and T2DM subjects. Our data may thus provide the basis for future studies to unravel the mechanisms.</p

A Case with Myxoma Accompanying pericardial Cyst

Disease exhibiting an abnormal tumorous shadow on the pericardium in x-ray picture is rare, and that with pericardial cyst is still more scarce. Having encountered a case, suspected of pericardial cyst, which on surgical operation proved to be of pericardial diveaticle accompanied by myxoma, we presented details of our findings on this very rare case

A Case with Leiomyoma of the Jejunum

Leiomyoma of the small intestine is a rare lesion, and most cases are found during operation and during autopsy. This patiant who we reported had a history of melena. Oval filling defect was detected in the jejunum by means of conventional barium examination. The histologic type of this neoplasm could be suggested by its radiologic findings and probed by operation

A Case with Esophageal Leiomyoma

Leiomyoma of the esophagus is a rare lesion. On this case that we reported, the right oblique chest radiogram showed the soft tissue mass in the mediastinum. The diagnosis was made by the barium swallow study. In this report, we chiefly discussed about the radiologic findings of the esophageal leiomyoma and differential diagnosis with extraesophageal tumors