53 research outputs found
Using the Internet for Organizational Research: A Study of Cynicism in the Workplace
The Internet can be a valuable data collection tool for organizational psychology researchers. It can be less expensive than traditional paper-and-pencil survey methods, and the potential pool of participants is much larger. In addition, it can be used in situations where traditional data collection methods are not feasible, such as research involving sensitive issues such as negative employee attitudes or deviant behaviors at work. In this study, we examined the organizational attitudes of employees from various companies using (a) a snowball sample, who completed a traditional paper and pencil survey (n = 135), and (b) a sample recruited over the Internet, who completed an on-line survey (n = 220). Participants in both the non- Internet and the Internet group were asked to describe a negative incident involving their company, and answer a number of questions regarding how they felt about their company and how they behaved toward their company following the negative event. They also completed measures of organizational cynicism and job satisfaction. The two groups were compared on demographic characteristics and on their attitudes toward their organization. There were very few demographic differences between the two groups. The Internet group tended to be more cynical and to judge their organization more harshly than the non-Internet group; however, the response patterns of both groups were similar. These results suggest that, when used with caution, the Internet can be a viable method of conducting organizational research
Seamounts and Guyouts: A Unique Resource - The Necessity for Express Recognition in the Formulation of an International Regime of the Seabed
With dwindling natural resources, the international community needs a legal regime to regulate the exploration of seabed resources, notably seamounts and guyouts. This Article evaluates the legal status of seamounts and guyouts under international law with suggestions on the possible uses of these phenomena, while also attempting to formulate and assess a legal regime that properly recognizes the different characteristics of the sea bed from land formations. The geological characteristics of Seamounts and guyouts are important to any legal consideration. Because seamounts and guyouts are underwater mountains formed by volcanic activity, they have many possible uses, such as for research, military bases, mineral resource development, transportation, fishing, communications, weather forecasting, territorial expansion. These possible uses prompt the necessity for determining the legal status of seamounts and guyouts, which has been lacking in current international conventions. Thus, this Article concludes by recommending the creation of an international legal organization, the International Oceans Agency, that will control the seabed
Defining Anuran Malformations in the Context of a Developmental Problem
This paper summarizes terminology and general concepts involved in animal development for the purpose of providing background for the study and understanding of frog malformations. The results of our radiographic investigation of rear limb malformations in Rana pipiens provide evidence that frog malformations are the product of early developmental errors. Although bacteria, parasites and viruses were identified in these metamorphosed frogs, the relevant window to look for the teratogenic affect of these agents is in the early tadpole stage during limb development. As a result, our microbiological findings must be regarded as inconclusive relative to determining their contribution to malformations because we conducted our examinations on metamorphosed frogs not tadpoles. Future studies need to look at teratogenic agents (chemical, microbial, physical or mechanical) that are present in the embryo, tadpole, and their environments at stages of development that are relevant for the malformation type. The impact of these teratogenic agents then needs to be assessed in appropriate animal models using studies that are designed to mimic field conditions. The results of these laboratory tests should then be analyzed in such a way that will allow comparison with the findings in the wild-caught tadpoles and frogs
Evaluation and Comparison of Food Records, Recalls, and Frequencies for Energy and Protein Assessment by Using Recovery Biomarkers
The food frequency questionnaire approach to dietary assessment is ubiquitous in nutritional epidemiology research. Food records and recalls provide approaches that may also be adaptable for use in large epidemiologic cohorts, if warranted by better measurement properties. The authors collected (2007–2009) a 4-day food record, three 24-hour dietary recalls, and a food frequency questionnaire from 450 postmenopausal women in the Women’s Health Initiative prospective cohort study (enrollment, 1994–1998), along with biomarkers of energy and protein consumption. Through comparison with biomarkers, the food record is shown to provide a stronger estimate of energy and protein than does the food frequency questionnaire, with 24-hour recalls mostly intermediate. Differences were smaller and nonsignificant for protein density. Food frequencies, records, and recalls were, respectively, able to “explain” 3.8%, 7.8%, and 2.8% of biomarker variation for energy; 8.4%, 22.6%, and 16.2% of biomarker variation for protein; and 6.5%, 11.0%, and 7.0% of biomarker variation for protein density. However, calibration equations that include body mass index, age, and ethnicity substantially improve these numbers to 41.7%, 44.7%, and 42.1% for energy; 20.3%, 32.7%, and 28.4% for protein; and 8.7%, 14.4%, and 10.4% for protein density. Calibration equations using any of the assessment procedures may yield suitable consumption estimates for epidemiologic study purposes
Pervasive Sharing of Genetic Effects in Autoimmune Disease
Genome-wide association (GWA) studies have identified numerous, replicable, genetic associations between common single nucleotide polymorphisms (SNPs) and risk of common autoimmune and inflammatory (immune-mediated) diseases, some of which are shared between two diseases. Along with epidemiological and clinical evidence, this suggests that some genetic risk factors may be shared across diseases—as is the case with alleles in the Major Histocompatibility Locus. In this work we evaluate the extent of this sharing for 107 immune disease-risk SNPs in seven diseases: celiac disease, Crohn's disease, multiple sclerosis, psoriasis, rheumatoid arthritis, systemic lupus erythematosus, and type 1 diabetes. We have developed a novel statistic for Cross Phenotype Meta-Analysis (CPMA) which detects association of a SNP to multiple, but not necessarily all, phenotypes. With it, we find evidence that 47/107 (44%) immune-mediated disease risk SNPs are associated to multiple—but not all—immune-mediated diseases (SNP-wise PCPMA<0.01). We also show that distinct groups of interacting proteins are encoded near SNPs which predispose to the same subsets of diseases; we propose these as the mechanistic basis of shared disease risk. We are thus able to leverage genetic data across diseases to construct biological hypotheses about the underlying mechanism of pathogenesis
Caul
Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. Correspondence to: Kimberly Eaton Hoagwood
- …