A kiloparsec-scale nuclear stellar disk in the milky way as a possible explanation of the high velocity peaks in the galactic bulge

The Apache Point Observatory Galactic Evolution Experiment has measured the stellar velocities of red giant stars in the inner Milky Way. We confirm that the line of sight velocity distributions (LOSVDs) in the mid-plane exhibit a second peak at high velocities, whereas those at | b| =2^\circ do not. We use a high resolution simulation of a barred galaxy, which crucially includes gas and star formation, to guide our interpretation of the LOSVDs. We show that the data are fully consistent with the presence of a thin, rapidly rotating, nuclear disk extending to ∼1 kpc. This nuclear disk is orientated perpendicular to the bar and is likely to be composed of stars on x2 orbits. The gas in the simulation is able to fall onto such orbits, leading to stars populating an orthogonal disk

An evaluation of the integration of non-traditional learning tools into a community based breast and cervical cancer education program: The witness project of Buffalo

BACKGROUND: Breast and cervical cancer continue to represent major health challenges for African American women. among Caucasian women. The underlying reasons for this disparity are multifactorial and include lack of education and awareness of screening and early detection. Traditional educational methods have enjoyed varied success in the African American community and spawned development of novel educational approaches. Community based education programs employing a variety of educational models have been introduced. Successful programs must train and provide lay community members with the tools necessary to deliver strong educational programs. METHODS: The Witness Project is a theory-based, breast and cervical cancer educational program, delivered by African American women, that stresses the importance of early detection and screening to improve survival and teaches women how to perform breast self examination. Implementing this program in the Buffalo Witness Project of Buffalo required several modifications in the curriculum, integration of non-traditional learning tools and focused training in clinical study participation. The educational approaches utilized included repetition, modeling, building comprehension, reinforcement, hands on learning, a social story on breast health for African American women, and role play conversations about breast and cervical health and support. RESULTS: Incorporating non-traditional educational approaches into the Witness Project training resulted in a 79% improvement in the number of women who mastered the didactic information. A seventy-two percent study participation rate was achieved by educating the community organizations that hosted Witness Project programs about the informed consent process and study participation. CONCLUSION: Incorporating non-traditional educational approaches into community outreach programs increases training success as well as community participation

Zoneamento Agroecológico do município de Ponta Porã/MS.

bitstream/item/25433/1/bpd137-2009-ponta-pora-ms.pd

Zoneamento Agroecológico do município de Bonito/MS.

A Embrapa Solos em parceria com a Secretaria de Estado de Desenvolvimento Agrário, da Produção, da Indústria, do Comércio e do Turismo - SEPROTUR realizou o Zoneamento Agroecológico do Estado do Mato Grosso do Sul ? Fase I - com objetivo de contribuir na indicação de áreas passíveis de exploração agrícola sustentável. No desenvolvimento desse trabalho foram considerados aspectos legais, restrições ambientais, potencial das culturas, aspectos do clima, de geomorfologia e dos solos. Esses parâmetros estão integrados em ambiente de sistema de informação geográfica com apoio de algebra de mapas, no intuito de avaliar a adequabilidade de uso das terras e apresentar uma proposição de planejamento de uso e ocupação das terras. Os resultados desse trabalho foram consolidados por município e dão origem a esse boletim de pesquisa. As terras indicadas para o uso com lavouras somam cerca de 280.000 ha, correspondendo a aproximadamente 66,5% da área total do município, enquanto que as recomendadas equivalentem a 22,7% e as áreas recomendadas para pastagem especial ou cultivo de arroz correspondem a aproximadamente 8% da área do município que corresponde a algo como 40.000 hectares. Nestas unidades é fundamental avaliar-se criteriosamente a utilização de pastagens nestas terras quando essas ainda se encontram sob cobertura vegetal, visto que, praticamente 50% destas terras ainda permanecem com vegetação natural em seus diversos graus de conservação. As terras recomendadas para conservação dos recursos naturais e/ou recuperação ambiental somam quase 30.000 ha, as quais constituem áreas de alta fragilidade ambiental e/ou apresentam restrições legais de uso como áreas de preservação permanente.bitstream/item/103010/1/BPD-145-Bonito-MS.pd

Zoneamento Agroecológico do município de Guia Lopes da Laguna - MS.

bitstream/item/25441/1/bpd146-2009-guia-lopes-ms.pd

Deformations of nearly Kähler instantons

We formulate the deformation theory for instantons on nearly Kähler six-manifolds using spinors and Dirac operators. Using this framework we identify the space of deformations of an irreducible instanton with semisimple structure group with the kernel of an elliptic operator, and prove that abelian instantons are rigid. As an application, we show that the canonical connection on three of the four homogeneous nearly Kähler six-manifolds G/H is a rigid instanton with structure group H. In contrast, these connections admit large spaces of deformations when regarded as instantons on the tangent bundle with structure group SU(3)

Enhancing Next-Generation Sequencing-Guided Cancer Care Through Cognitive Computing

Background: Using next-generation sequencing (NGS) to guide cancer therapy has created challenges in analyzing and reporting large volumes of genomic data to patients and caregivers. Specifically, providing current, accurate information on newly approved therapies and open clinical trials requires considerable manual curation performed mainly by human “molecular tumor boards” (MTBs). The purpose of this study was to determine the utility of cognitive computing as performed by Watson for Genomics (WfG) compared with a human MTB. Materials and Methods: One thousand eighteen patient cases that previously underwent targeted exon sequencing at the University of North Carolina (UNC) and subsequent analysis by the UNCseq informatics pipeline and the UNC MTB between November 7, 2011, and May 12, 2015, were analyzed with WfG, a cognitive computing technology for genomic analysis. Results: Using a WfG-curated actionable gene list, we identified additional genomic events of potential significance (not discovered by traditional MTB curation) in 323 (32%) patients. The majority of these additional genomic events were considered actionable based upon their ability to qualify patients for biomarker-selected clinical trials. Indeed, the opening of a relevant clinical trial within 1 month prior to WfG analysis provided the rationale for identification of a new actionable event in nearly a quarter of the 323 patients. This automated analysis took <3 minutes per case. Conclusion: These results demonstrate that the interpretation and actionability of somatic NGS results are evolving too rapidly to rely solely on human curation. Molecular tumor boards empowered by cognitive computing could potentially improve patient care by providing a rapid, comprehensive approach for data analysis and consideration of up-to-date availability of clinical trials. Implications for Practice: The results of this study demonstrate that the interpretation and actionability of somatic next-generation sequencing results are evolving too rapidly to rely solely on human curation. Molecular tumor boards empowered by cognitive computing can significantly improve patient care by providing a fast, cost-effective, and comprehensive approach for data analysis in the delivery of precision medicine. Patients and physicians who are considering enrollment in clinical trials may benefit from the support of such tools applied to genomic data