31 research outputs found

    Development of catecholamine and cortisol stress responses in zebrafish.

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    Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus-pituitary-adrenal (HPA) axis and the sympathetic-adrenomedullary system, though the correlation with activation and development is not well understood. We evaluated the stress response of both cortisol and catecholamines during development in zebrafish. Zebrafish at two different stages of development were stressed in one of two different ways and cortisol and catecholamine were measured. Cortisol was measured by enzyme immune assay and catecholamine was measured by ELISA. Our results show that stress responses are delayed until after the synthesis of both cortisol and catecholamines. These observations suggest that the development of HPA axis may be required for the acquisition of the stress response for cortisol and catecholamines

    A Preliminary Examination of Effect of Massage and Aroma Oil Massage in Foot Care Nursing

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    AbstractFoot care nursing is attracting attention as a medically effective treatment for the foot lesions caused by such problems as diabetes or aging. In this study, we experimentally examined how aromatherapy affects human brain functions during foot care nursing using near-infrared spectroscopy (NIRS). 11 subjects received both foot care nursing massages and aroma oil massages. We analyzed the changes in their oxygenated hemoglobin (oxy-Hb) concentrations based on their brain activity by t-tests, and the t-test results showed significant differences between two kinds of massages in both the somatosensory and prefrontal association areas. The oxy-Hb concentration in both massages with and without aroma oil also showed a tendency to decrease with time. Our questionnaire results showed that our subjects felt more comfortable and relaxed while receiving foot care nursing with aroma oils. These results suggest that aroma oil massages are an effective foot care nursing tool and that foot care nursing is a medically effective treatment

    Short Report: Herpes-Like DNA Sequences in African-Endemic and Acquired Immunodeficiency Syndrome-Associated Kaposi\u27s Sarcoma

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    Recently, the unique nucleic acid closely related to the herpes-like sequences has been found in acquired immunodeficiency syndrome (AIDS)-associated Kaposi\u27s sarcoma (KS). We have confirmed the presence of herpes-like DNA sequences in six cases of AIDS-associated KS and three of the nine cases of African-endemic KS in adults, but not in eight cases of KS in children from the same area. These sequences were seen in a histologically early stage of KS. Our results suggest that herpes-like DNA sequences may play an important role in the pathogenesis of AIDS-associated KS

    Learning Outcomes and Career of Graduates of Information Sociology : Focusing on Results of the Web Tracer Study System

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    本研究は,学科設立から10年を迎えたのを機に,学科教育の評価者でもありサポーターでもある卒業生を対象とした悉皆調査を行うことで,学科教育に対する点検・評価,IR 活動の一環として今後の学科教育の改善を検討することが目的である.調査方法は,卒業生に調査依頼状とweb 回答が可能な個別ID とパスワードを発行し,各自が回答を行うweb システムによるアンケート調査を実施した.調査の結果から,在学時の学修状況としては,授業には真面目に出席しているが,授業外での学習はほとんど行っておらず,学科の教育・指導で充実していたと評価しているものは,「専門の授業」や「卒業論文」,「ゼミ活動」であり,自分が熱心に取り組んだ活動も「卒業論文」,「専門の授業」,「ゼミ活動」であった.卒業後の進路は,約9割が就職をしており,約8割が正規雇用として就業していた.その中で,初職を継続している者は約6割であった.在学時に獲得した能力では「PC を活用する能力」であるが,現在の仕事で必要とされている能力は,知識や技能ではなく「基礎的・社会的な技能」や「統合的な学習知識と創造的な思考力」などの能力であった.大学教育での効用としては,人格を形成する上で重要だったと考えており,78.9%の卒業生が総合的に振り返って学科教育に満足していると回答していた

    Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

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