Knowledge, attitude and intending practice of female undergraduates about breastfeeding

The recommendation by the World Health Organization (WHO) is that infants should be fed exclusively on breast milk for the first 6 months, but the rate of exclusive breastfeeding (EBF) has been on the decline in Nigeria. The study determines knowledge, attitude and intending practice of unmarried female undergraduates about breastfeeding (BF). Two  hundred females were selected using the simple random sampling  procedure. Interview schedule was used to obtain information on socio-economic characteristics, knowledge, attitude and intending practices of EBF of Obafemi Awolowo University Ile Ife, Nigeria. Knowledge and attitudes on BF were determined using a three and five point Likert Scale, respectively. Data was described using percentages, frequency counts and regression. Sixty percent of the respondents were between the ages of 21 and 24years and more than half are four hundred level students (54.5%). Knowledge on the term EBF is misconstrued as BF for 12 months by 33% of the respondents. Women intend to initiate BF between the first 0-6 hour of birth (65%) and breast feed on request (62.5%). However, 61% may not practice EBF because of their jobs, will introduce infant formula or water during the first six months and 38.3% will not breast feed in public. Women intend to terminate BF at 3 months (5.0%), 6 months (16.5%), 1 year (50.5%) and 2 years (28.0%) because of their health status (54.0%). Knowledge about BF was average (94%) and attitude was neutral (77.4%).Women intend to manage EBF during working hours by having fixed feeding schedules (14.0%) and using expressed breast milk (16.0%). About 34.5% of respondents will not use expressed breast milk because of fear of contamination (42.0%) and their health (36.3%), 6.0% expressed the opinion that EBF is not possible. Major influence on BF decisions includes maternal health (59.7%), maternal jobs (54.4%), husbands (34.5%), mother (24.8%), and mothers in law (17.5%). Regression analysis revealed that knowledge (b=-0.025) has a negative significant relationship with duration of EBF of mothers at p <0.05. It is concluded that women lacked understanding of the BF recommendations, duration of EBF, have average knowledge and neutral attitude towards EBF. It is recommended that child health matters should be taught not only in the medical schools, but special courses should be offered to increase knowledge on appropriate recommendations on BF practices for all students.Key words: undergraduate, attitude, knowledge, practice, breastfeedin

Midgut Barrier Imparts Selective Resistance to Filarial Worm Infection in Culex pipiens pipiens

Mosquitoes in the Culex pipiens complex thrive in temperate and tropical regions worldwide, and serve as efficient vectors of Bancroftian lymphatic filariasis (LF) caused by Wuchereria bancrofti in Asia, Africa, the West Indies, South America, and Micronesia. However, members of this mosquito complex do not act as natural vectors for Brugian LF caused by Brugia malayi, or for the cat parasite B. pahangi, despite their presence in South Asia where these parasites are endemic. Previous work with the Iowa strain of Culex pipiens pipiens demonstrates that it is equally susceptible to W. bancrofti as is the natural Cx. p. pipiens vector in the Nile Delta, however it is refractory to infection with Brugia spp. Here we report that the infectivity barrier for Brugia spp. in Cx. p. pipiens is the mosquito midgut, which inflicts internal and lethal damage to ingested microfilariae. Following per os Brugia exposures, the prevalence of infection is significantly lower in Cx. p. pipiens compared to susceptible mosquito controls, and differs between parasite species with <50% and <5% of Cx. p. pipiens becoming infected with B. pahangi and B. malayi, respectively. When Brugia spp. mf were inoculated intrathoracically to bypass the midgut, larvae developed equally well as in controls, indicating that, beyond the midgut, Cx. p. pipiens is physiologically compatible with Brugia spp. Mf isolated from Cx. p. pipiens midguts exhibited compromised motility, and unlike mf derived from blood or isolated from the midguts of Ae. aegypti, failed to develop when inoculated intrathoracically into susceptible mosquitoes. Together these data strongly support the role of the midgut as the primary infection barrier for Brugia spp. in Cx. p. pipiens. Examination of parasites recovered from the Cx. p. pipiens midgut by vital staining, and those exsheathed with papain, suggest that the damage inflicted by the midgut is subcuticular and disrupts internal tissues. Microscopic studies of these worms reveal compromised motility and sharp bends in the body; and ultrastructurally the presence of many fluid or carbohydrate-filled vacuoles in the hypodermis, body wall, and nuclear column. Incubation of Brugia mf with Cx. p. pipiens midgut extracts produces similar internal damage phenotypes; indicating that the Cx. p. pipiens midgut factor(s) that damage mf in vivo are soluble and stable in physiological buffer, and inflict damage on mf in vitro

The meaning, symptoms and perceptual cause of onchodermatitis among Yoruba rural dwellers

No Abstract

Nigeria Anopheles vector database: an overview of 100 years' research.

Anopheles mosquitoes are important vectors of malaria and lymphatic filariasis (LF), which are major public health diseases in Nigeria. Malaria is caused by infection with a protozoan parasite of the genus Plasmodium and LF by the parasitic worm Wuchereria bancrofti. Updating our knowledge of the Anopheles species is vital in planning and implementing evidence based vector control programs. To present a comprehensive report on the spatial distribution and composition of these vectors, all published data available were collated into a database. Details recorded for each source were the locality, latitude/longitude, time/period of study, species, abundance, sampling/collection methods, morphological and molecular species identification methods, insecticide resistance status, including evidence of the kdr allele, and P. falciparum sporozoite rate and W. bancrofti microfilaria prevalence. This collation resulted in a total of 110 publications, encompassing 484,747 Anopheles mosquitoes in 632 spatially unique descriptions at 142 georeferenced locations being identified across Nigeria from 1900 to 2010. Overall, the highest number of vector species reported included An. gambiae complex (65.2%), An. funestus complex (17.3%), An. gambiae s.s. (6.5%). An. arabiensis (5.0%) and An. funestus s.s. (2.5%), with the molecular forms An. gambiae M and S identified at 120 locations. A variety of sampling/collection and species identification methods were used with an increase in molecular techniques in recent decades. Insecticide resistance to pyrethroids and organochlorines was found in the main Anopheles species across 45 locations. Presence of P. falciparum and W. bancrofti varied between species with the highest sporozoite rates found in An. gambiae s.s, An. funestus s.s. and An. moucheti, and the highest microfilaria prevalence in An. gambiae s.l., An. arabiensis, and An. gambiae s.s. This comprehensive geo-referenced database provides an essential baseline on Anopheles vectors and will be an important resource for malaria and LF vector control programmes in Nigeria