167 research outputs found
TEMPLATES: A Robust Outlier Rejection Method for JWST/NIRSpec Integral Field Spectroscopy
We describe a custom outlier rejection algorithm for JWST/NIRSpec integral
field spectroscopy. This method uses a layered sigma clipping approach that
adapts clipping thresholds based upon the spatial profile of the science
target. We find that this algorithm produces a robust outlier rejection while
simultaneously preserving the signal of the science target. Originally
developed as a response to unsatisfactory initial performance of the jwst
pipeline outlier detection step, this method works either as a standalone
solution, or as a supplement to the current pipeline software. Comparing
leftover (i.e., not flagged) artifacts with the current pipeline's outlier
detection step, we find that our method results in one fifth as many residual
artifacts as the jwst pipeline. However, we find a combination of both methods
removes nearly all artifacts -- an approach that takes advantage of both our
algorithm's robust outlier rejection and the pipeline's use of individual
dithers. This combined approach is what the TEMPLATES Early Release Science
team has converged upon for our NIRSpec observations. Finally, we publicly
release the code and Jupyter notebooks for the custom outlier rejection
algorithm.Comment: 10 pages, including 5 figures. Submitted to the Publications of the
Astronomical Society of the Pacific (PASP). Code associated with paper
released at https://github.com/aibhleog/baryon-swee
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Compassionate pedagogy: the ethics of care in early childhood professionalism
This paper builds upon an earlier attempt (Taggart, 2011) to articulate a rationale for professional training in early childhood education and care (ECEC) which is ethical as opposed to one which is purely instrumental or rooted in a patriarchal notion of women’s supposed unique suitability. The argument proposes that a feminist approach to ethics, as both socially critical and psychologically affective or flexible, has a particular relevance to professional identity in ECEC. In particular, compassion, as a concept which has both sociological and psychological connotations, foregrounds the ethical dimension of the work whilst overcoming false dichotomies between discourses of ‘children’s rights’ and ‘care’. The implications for the training and professional identity of practitioners are discussed
Thoracic CT findings of novel influenza A (H1N1) infection in immunocompromised patients
The goal of this study is to describe the spectrum of initial and follow-up CT findings of novel influenza A (H1N1) infection in a series of immunocompromised patients. Eight immunocompromised patients with documented novel influenza A (H1N1) had CT imaging at our institution between May 2009 and August 2009. A total of 20 CTs (initial and follow-up) were reviewed for the presence, severity, and distribution of the following: ground glass opacity, consolidation, interlobular septal thickening, mosaic perfusion, airway wall thickening, airway dilatation, nodules, cysts, pleural effusion, pericardial effusion, lymphadenopathy, and air trapping. The most common findings were airway thickening/dilatation, peribronchial ground glass opacity, centrilobular nodules, and tree-in-bud opacities. Peripheral consolidation involving the lower lobes was also a common pattern. Findings frequently involved all lobes and were closely associated with either large or small airways. Two patients presented with atypical CT findings including focal lobar consolidation and patchy lower lobe consolidation with soft tissue centrilobular nodules. Most survivors showed near complete resolution of findings within 35Â days. CT scans in immunocompromised patients with novel influenza H1N1 commonly show a strong airway predominance of findings or peripheral areas of consolidation involving the lower lobes. A subset of patients with novel influenza A (H1N1) will show findings not typical of viral infection
Transcriptional Response of Zebrafish Embryos Exposed to Neurotoxic Compounds Reveals a Muscle Activity Dependent hspb11 Expression
Acetylcholinesterase (AChE) inhibitors are widely used as pesticides and drugs. Their primary effect is the overstimulation of cholinergic receptors which results in an improper muscular function. During vertebrate embryonic development nerve activity and intracellular downstream events are critical for the regulation of muscle fiber formation. Whether AChE inhibitors and related neurotoxic compounds also provoke specific changes in gene transcription patterns during vertebrate development that allow them to establish a mechanistic link useful for identification of developmental toxicity pathways has, however, yet not been investigated. Therefore we examined the transcriptomic response of a known AChE inhibitor, the organophosphate azinphos-methyl (APM), in zebrafish embryos and compared the response with two non-AChE inhibiting unspecific control compounds, 1,4-dimethoxybenzene (DMB) and 2,4-dinitrophenol (DNP). A highly specific cluster of APM induced gene transcripts was identified and a subset of strongly regulated genes was analyzed in more detail. The small heat shock protein hspb11 was found to be the most sensitive induced gene in response to AChE inhibitors. Comparison of expression in wildtype, ache and sopfixe mutant embryos revealed that hspb11 expression was dependent on the nicotinic acetylcholine receptor (nAChR) activity. Furthermore, modulators of intracellular calcium levels within the whole embryo led to a transcriptional up-regulation of hspb11 which suggests that elevated intracellular calcium levels may regulate the expression of this gene. During early zebrafish development, hspb11 was specifically expressed in muscle pioneer cells and Hspb11 morpholino-knockdown resulted in effects on slow muscle myosin organization. Our findings imply that a comparative toxicogenomic approach and functional analysis can lead to the identification of molecular mechanisms and specific marker genes for potential neurotoxic compounds
Child Care for Working Poor Families: Child Development and Parent Employment Outcomes: Community Child Care Research Project, Final Report
The results of the Community Child Care Research Project provide new data describing the child care experiences of low income working families in 4 communities in Indiana. Because the study participants were volunteers rather than randomly selected, and because the research design was correlational rather than experimental, conclusions drawn from these fi ndings necessarily have limitations. The fi ndings cannot be confi dently generalized to other low income working families and child care providers, nor can the links between child care quality and children’s development be assumed to be causal. For example, while it is quite possible that higher quality child care does support better child development outcomes, it is also plausible that families whose children have more advanced levels of development found and used higher quality child care. Despite these limitations, the research results do represent the recent experiences of more than 300 low income working families, their children, and their child care providers. The results suggest a number of key issues that need further investigation by policy makers and researchers
Do Student Perceptions of Diversity Emphasis Relate to Learning of Psychology?
We examined the extent to which students\u27 perceived inclusion of diversity issues in the Introduction to Psychology course related to perceptions of learning. Based on the responses of 625 students, multilevel linear modeling analyses revealed that student perceptions of diversity emphasis in the class were positively related to how well students believed they understood concepts and the extent to which they believed they learned concepts they could apply to their lives. We also examined the relation between individual differences (e.g., age, race) and perceived learning. We discuss the importance of including issues of diversity in psychology classes
The Parent–Caregiver Relationship Scale: Rounding Out the Relationship System in Infant Child Care
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