56 research outputs found
The coupling constant g as derived from QCD sum rules
We employ QCD sum rules to calculate the coupling constant
g by studying the three point
-correlation function. Our results is consistent with the
value of this coupling constant obtained using vector meson dominance of the
electromagnetic current and the experimental -photoproduction data.Comment: 10 pages RevTex, 3 postscript figure
Decay constants, light quark masses and quark mass bounds from light quark pseudoscalar sum rules
The flavor and pseudoscalar correlators are investigated using
families of finite energy sum rules (FESR's) known to be very accurately
satisfied in the isovector vector channel. It is shown that the combination of
constraints provided by the full set of these sum rules is sufficiently strong
to allow determination of both the light quark mass combinations ,
and the decay constants of the first excited pseudoscalar mesons in
these channels. The resulting masses and decay constants are also shown to
produce well-satisfied Borel transformed sum rules, thus providing non-trivial
constraints on the treatment of direct instanton effects in the FESR analysis.
The values of and obtained are in good agreement with the
values implied by recent hadronic decay analyses and the ratios obtained
from ChPT. New light quark mass bounds based on FESR's involving weight
functions which strongly suppress spectral contributions from the excited
resonance region are also presented.Comment: 28 pages, 10 figure
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
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