An Emotional Support System for Collaborative Networks

Part 2: Collaborative NetworksInternational audienceA particular challenge in the management of collaborative networks is the effective handling of the interactions among participants, especially in what concerns the management of “soft” issues that are not currently available in the execution processes of such networks. These issues can include inter- and intra-organizational abilities, problems in keeping team cohesion, leadership, among others. Moreover, one cannot forget that organizations are composed of people, and people have intrinsically associated emotions which are present in all interactions. In this sense, when not properly handled, some participant’s emotions might put in jeopardy the quality of the collaboration. On the other hand the collective emotional state of the collaborative network can also affect each participant’s emotions. As a contribution to keep the emotional equilibrium of the network, this paper presents the design of an emotional support system, including the identification and categorization of the most influencing positive and negative collective emotions and also the specification and prototyping of the sub-system services

Neuroepigenetic signatures of age and sex in the living human brain

Age- and sex-related alterations in gene transcription have been demonstrated, however the underlying mechanisms are unresolved. Neuroepigenetic pathways regulate gene transcription in the brain. Here, we measure in vivo expression of the epigenetic enzymes, histone deacetylases (HDACs), across healthy human aging and between sexes using [11C]Martinostat positron emission tomography (PET) neuroimaging (n = 41). Relative HDAC expression increases with age in cerebral white matter, and correlates with age-associated disruptions in white matter microstructure. A post mortem study confirmed that HDAC1 and HDAC2 paralogs are elevated in white matter tissue from elderly donors. There are also sex-specific in vivo HDAC expression differences in brain regions associated with emotion and memory, including the amygdala and hippocampus. Hippocampus and white matter HDAC expression negatively correlates with emotion regulation skills (n = 23). Age and sex are associated with HDAC expression in vivo, which could drive age- and sex-related transcriptional changes and impact human behavior

Turkey

This chapter reviews irrigation development and policy with specific references to the main water- and land-based regional socioeconomic development projects in Turkey. It analyzes the expansion of irrigation investment as well as institutional and technological changes in irrigation policy and development in parallel with policies of liberalization and decentralization in the late 1980s. The chapter also discusses institutional changes in the management of the irrigation systems as a result of (partial) transfer of management of large-scale irrigation systems to a variety of water user organizations. Finally, it describes current technological and institutional problems and the further challenges to the irrigation sector, such as infrastructure deterioration, risks of drought, environmental and ecological system degradation, and insufficient investment. It also notes the efforts to equip new irrigation schemes with modern technology, such as closed pipes for conveying water instead of open channels, and water-saving micro-irrigation methods rather than surface irrigation techniques.WOS:000486992000009Scopus - Affiliation ID: 60105072Book Citation Index- Science - Book Citation Index- Social Sciences and HumanitiesArticle; Book ChapterNisan2019YÖK - 2018-1

Pre-analytical issues in the haemostasis laboratory: guidance for the clinical laboratories

Ensuring quality has become a daily requirement in laboratories. In haemostasis, even more than in other disciplines of biology, quality is determined by a pre-analytical step that encompasses all procedures, starting with the formulation of the medical question, and includes patient preparation, sample collection, handling,transportation, processing, and storage until time of analysis. This step, based on a variety of manual activities, is the most vulnerable part of the total testing process and is a major component of the reliability and validity of results in haemostasis and constitutes the most important source of erroneous or un-interpretable results. Pre-analytical errors may occur throughout the testing process and arise from unsuitable, inappropriate or wrongly handled procedures. Problems may arise during the collection of blood specimens such as misidentification of the sample, use of inadequate devices or needles, incorrect order of draw, prolonged tourniquet placing, unsuccessful attempts to locate the vein, incorrect use of additive tubes, collection of unsuitable samples for quality or quantity, inappropriate mixing of a sample, etc. Some factors can alter the result of a sample constituent after collection during transportation, preparation and storage. Laboratory errors can often have serious adverse consequences. Lack of standardized procedures for sample collection accounts for most of the errors encountered within the total testing process. They can also have clinical consequences as well as a significant impact on patient care, especially those related to specialized tests as these are often considered as “diagnostic”. Controlling pre-analytical variables is critical since this has a direct influence on the quality of results and on their clinical reliability. The accurate standardization of the pre-analytical phase is of pivotal importance for achieving reliable results of coagulation tests and should reduce the side effects of the influence factors. This review is a summary of the most important recommendations regarding the importance of pre-analytical factors for coagulation testing and should be a tool to increase awareness about the importance of pre-analytical factors for coagulation testing