360 research outputs found
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A systematic methodology to assess the impact of human factors in ship design
Evaluating ship layout for human factors (HF) issues using simulation software such as maritimeEXODUS can be a long and complex process. The analysis requires the identification of relevant evaluation scenarios; encompassing evacuation and normal operations; the development of appropriate measures which can be used to gauge the performance of crew and vessel and finally; the interpretation of considerable simulation data. Currently, the only agreed guidelines for evaluating HFs performance of ship design relate to evacuation and so conclusions drawn concerning the overall suitability of a ship design by one naval architect can be quite different from those of another. The complexity of the task grows as the size and complexity of the vessel increases and as the number and type of evaluation scenarios considered increases. Equally, it can be extremely difficult for fleet operators to set HFs design objectives for new vessel concepts. The challenge for naval architects is to develop a procedure that allows both accurate and rapid assessment of HFs issues associated with vessel layout and crew operating procedures. In this paper we present a systematic and transparent methodology for assessing the HF performance of ship design which is both discriminating and diagnostic. The methodology is demonstrated using two variants of a hypothetical naval ship
The Role of Friction in Compaction and Segregation of Granular Materials
We investigate the role of friction in compaction and segregation of granular
materials by combining Edwards' thermodynamic hypothesis with a simple
mechanical model and mean-field based geometrical calculations. Systems of
single species with large friction coefficients are found to compact less.
Binary mixtures of grains differing in frictional properties are found to
segregate at high compactivities, in contrary to granular mixtures differing in
size, which segregate at low compactivities. A phase diagram for segregation
vs. friction coefficients of the two species is generated. Finally, the
characteristics of segregation are related directly to the volume fraction
without the explicit use of the yet unclear notion of compactivity.Comment: 9 pages, 6 figures, submitted to Phys. Rev.
A perspective on the landscape problem
I discuss the historical roots of the landscape problem and propose criteria
for its successful resolution. This provides a perspective to evaluate the
possibility to solve it in several of the speculative cosmological scenarios
under study including eternal inflation, cosmological natural selection and
cyclic cosmologies.Comment: Invited contribution for a special issue of Foundations of Physics
titled: Forty Years Of String Theory: Reflecting On the Foundations. 31
pages, no figure
Linear Sigma Models for Open Strings
We formulate and study a class of massive N=2 supersymmetric gauge field
theories coupled to boundary degrees of freedom on the strip. For some values
of the parameters, the infrared limits of these theories can be interpreted as
open string sigma models describing D-branes in large-radius Calabi-Yau
compactifications. For other values of the parameters, these theories flow to
CFTs describing branes in more exotic, non-geometric phases of the Calabi-Yau
moduli space such as the Landau-Ginzburg orbifold phase. Some simple properties
of the branes (like large radius monodromies and spectra of worldvolume
excitations) can be computed in our model. We also provide simple worldsheet
models of the transitions which occur at loci of marginal stability, and of
Higgs-Coulomb transitions.Comment: 51 pages, 2 figures; very minor corrections, refs adde
Mental Health Changes Over Time: a Longitudinal Perspective: Summary Report: Mental Health and Wellbeing Transition Study
Bryant, R., Lawrence-Wood, E., Baur, J., McFarlane, A., Hodson, S., Sadler, N., Benassi, H., Howell, S., Abraham, M., Iannos, M., Hansen, C., Searle, A., Van Hooff, M
Mental Health Changes Over Time: a Longitudinal Perspective: Mental Health and Wellbeing Transition Study
Bryant, R., Lawrence-Wood, E., Baur, J., McFarlane, A., Hodson, S., Sadler, N., Benassi, H., Howell, S., Abraham, M., Iannos, M., Hansen, C., Searle, A., Van Hooff, M
Multiwavelength studies of MHD waves in the solar chromosphere: An overview of recent results
The chromosphere is a thin layer of the solar atmosphere that bridges the
relatively cool photosphere and the intensely heated transition region and
corona. Compressible and incompressible waves propagating through the
chromosphere can supply significant amounts of energy to the interface region
and corona. In recent years an abundance of high-resolution observations from
state-of-the-art facilities have provided new and exciting ways of
disentangling the characteristics of oscillatory phenomena propagating through
the dynamic chromosphere. Coupled with rapid advancements in
magnetohydrodynamic wave theory, we are now in an ideal position to thoroughly
investigate the role waves play in supplying energy to sustain chromospheric
and coronal heating. Here, we review the recent progress made in
characterising, categorising and interpreting oscillations manifesting in the
solar chromosphere, with an impetus placed on their intrinsic energetics.Comment: 48 pages, 25 figures, accepted into Space Science Review
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
Análise da diversidade genética de isolados de Xanthomonas axonopodis pv. malvacearum do algodoeiro
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