Dr Murray's case of ligation of the abdominal aorta - Somerset Hospital, 1834 A forgotten historical event

While reading a recent anicle on the extraperitoneal exposure of the abdominal aona,l my attention was drawn to a comment in the discussion by Dr Charles Rob, who referred briefly to an operation carried out in Cape Town in 1834 by a Dr Murray. The operation consisted of the extraperitoneal exposure and ligation of the aona· for an expanding iliac aneurysm. The reference provided by Dr Rob was to a brief description entitled 'Dr Murray's case of ligature of the abdominal aona', which had appeared in the Annals of che Royal College of Surgeons of England in 1984.2 The original description of this operation is to be found in both the first (1839) and second editions (1850) of Surgical Anatomy of che Arteries and DescnjICive Anatomy of che Hearr by Valentine Flood.3 Despite the obvious historical significance of this operation, its performance is not recorded or noted in the standard texts that deal with the early history of medicine in the Cape,4-1 nor was its performance known to knowledgeable medical historians (J. H. Louw and J. c. de Villiers - personal communications)

Thrombotic side-effects of lower limb venography The use of heparin-saline flush

In a prospective study of 256 postoperative patients, bilateral lower limb venography was performed using meglumine iothalamate followed by heparin-saline flushing of the deep veins, and the complications of the procedure were assessed. No patient developed clinical evidence of deep-vein thrombosis after the venogram. In 117 patients fibrinogen uptake was performed 24 hours after the venogram. A new positive area on the uptake scan developed in 3 patients (2,6%). Local swelling or haematoma at the injection site occurred in 15 patients (5,9%), cellulitis in 2 (0,8%) and minor contrast reactions in 6 (2,3%). There were no major reactions and no procedure-related mortality. The reasons for the wide variation in the reported incidence of post-venogram thrombosis are considered and the importance of heparin-saline flushing of the deep veins to prevent this complication is discussed

Febrile polyarthritis and cutaneous nodules. An unusual presentation of a pancreatitis.

A case report of hidden pancreatitis with severe polyarthritis and necrosis of subcutaneous fat is presented. A brief review of this syndrome in the literature is also given. © 1984 Springer-Verlag.Case ReportsJournal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Reproducibility Project: Psychology

Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available

Data from: Estimating the reproducibility of psychological science

This record contains the underlying research data for the publication "Estimating the reproducibility of psychological science" and the full-text is available from: https://ink.library.smu.edu.sg/lkcsb_research/5257Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams