Letter from E.H. Taylor to James B. Finley

Rev. Edward H. Taylor has read some of Finley\u27s articles in the Christian Advocate & Journal and feels compelled to write to his old friend. He reports that his mother died on February 19, 1834. He has been part of the Pittsburgh Conference since it was organized but would greatly prefer an appointment in the Ohio Conference. Mrs. Taylor (Lydia Barstow) is doing well. They have six children, four sons and two daughters. Lydia writes her own note to Finley at the end of Edward\u27s letter. She has never really been happy in the Pittsburgh Conference and hopes that her special friends , Finley and Jacob Young, can suggest a transfer of Taylor to the Ohio Conference. Abstract Number - 1213https://digitalcommons.owu.edu/finley-letters/2193/thumbnail.jp

Letter from E.H. Taylor to James B. Finley

Rev. Edward H. Taylor writes to his old friend Finley to report that he is nearing the end of his itinerant travel. He is turning gray and his eyes are dim. He is currently traveling the Norwich Circuit, a line circuit (on the dividing line between the Pittsburgh and Ohio Conference). If there is a conference division in May, Taylor hopes that the Ohio Conference will take this territory back and give Marietta and Zanesville to the Pittsburgh Conference. Taylor then discusses the property issue related to the southern church. He opines that the General Conference of 1844 should have expelled Bishop Andrew and given no consent for the division of the church. The seceding south would then have shouldered the entire responsibility on their own. In closing, Taylor rants and raves about Freemasonry, which he argues is a \u27 Barbarous and Bloody System and all its oaths Profane. He is still astonished that Methodist preachers choose to join the Masons. Abstract Number - 631https://digitalcommons.owu.edu/finley-letters/1727/thumbnail.jp

Phylogenetic relationships of African Caecilians (Amphibia: Gymnophiona): insights from mitochondrial rRNA gene sequences

Africa (excluding the Seychelles) has a diverse caecilian fauna, including the endemic family Scolecomorphidae and six endemic genera of the more cosmopolitan Caeciliidae. Previous molecular phylogenetic studies have not included any caecilians from the African mainland. Partial 12S and 16S mitochondrial gene sequences were obtained for two species of the endemic African Scolecomorphidae and five species and four genera of African Caeciliids, aligned against previously reported sequences for 16 caecilian species, and analysed using parsimony, maximum likelihood, Bayesian and distance methods. Results are in agreement with traditional taxonomy in providing support for the monophyly of the African Caeciliid genera Boulengerula and Schistometopum and for the Scolecomorphidae. They disagree in indicating that the Caeciliidae is paraphyletic with respect to the Scolecomorphidae. Although more data from morphology and/or molecules will be required to resolve details of the interrelationships of the African caecilian genera, the data provide strong support for at least two origins of caecilians in which the eye is reduced and covered with bone, and do not support the hypotheses that the caecilian assemblages of Africa, and of East and of West Africa are monophyletic

Can one see the fundamental frequency of a drum?

We establish two-sided estimates for the fundamental frequency (the lowest eigenvalue) of the Laplacian in an open subset G of R^n with the Dirichlet boundary condition. This is done in terms of the interior capacitary radius of G which is defined as the maximal possible radius of a ball B which has a negligible intersection with the complement of G. Here negligibility of a subset F in B means that the Wiener capacity of F does not exceed gamma times the capacity of B, where gamma is an arbitrarily fixed constant between 0 and 1. We provide explicit values of constants in the two-sided estimates.Comment: 18 pages, some misprints correcte

On the global hydration kinetics of tricalcium silicate cement

We reconsider a number of measurements for the overall hydration kinetics of tricalcium silicate pastes having an initial water to cement weight ratio close to 0.5. We find that the time dependent ratio of hydrated and unhydrated silica mole numbers can be well characterized by two power-laws in time, $x/(1-x)\sim (t/t_x)^\psi$. For early times $t < t_x$ we find an `accelerated' hydration ($\psi = 5/2$) and for later times $t > t_x$ a `deaccelerated' behavior ($\psi = 1/2$). The crossover time is estimated as $t_x \approx 16 hours$. We interpret these results in terms of a global second order rate equation indicating that (a) hydrates catalyse the hydration process for $t<t_x$, (b) they inhibit further hydration for $t > t_x$ and (c) the value of the associated second order rate constant is of magnitude 6x10^{-7} - 7x10^{-6} liter mol^{-1} s^{-1}. We argue, by considering the hydration process actually being furnished as a diffusion limited precipitation that the exponents $\psi = 5/2$ and $\psi = 1/2$ directly indicate a preferentially `plate' like hydrate microstructure. This is essentially in agreement with experimental observations of cellular hydrate microstructures for this class of materials.Comment: RevTeX macros, 6 pages, 4 postscript figure

In Situ Measurements of Interstellar Dust

We present the mass distribution of interstellar grains measured in situ by the Galileo and Ulysses spaceprobes as cumulative flux. The derived in situ mass distribution per logarithmic size interval is compared to the distribution determined by fitting extinction measurements. Large grains measured in situ contribute significantly to the overall mass of dust in the local interstellar cloud. The problem of a dust-to-gas mass ratio that contradicts cosmic abundances is discussed.Comment: 4 pages and two figure

Best Practices for Virtual Care: A Consensus Statement From the Canadian Rheumatology Association

Objective. To develop best practice statements for the provision of virtual care in adult and pediatric rheumatology for the Canadian Rheumatology Association\u27s (CRA) Telehealth Working Group (TWG). Methods. Four members of the TWG representing adult, pediatric, university-based, and community rheumatology practices defined the scope of the project. A rapid literature review of existing systematic reviews, policy documents, and published literature and abstracts on the topic was conducted between April and May 2021. The review informed a candidate set of 7 statements and a supporting document. The statements were submitted to a 3-round (R) modified Delphi process with 22 panelists recruited through the CRA and patient advocacy organizations. Panelists rated the importance and feasibility of the statements on a Likert scale of 1-9. Statements with final median ratings between 7-9 with no disagreement were retained in the final set. Results. Twenty-one (95%) panelists participated in R1, 15 (71%) in R2, and 18 (82%) in R3. All but 1 statement met inclusion criteria during R1. Revisions were made to 5/7 statements following R2 and an additional statement was added. All statements met inclusion criteria following R3. The statements addressed the following themes in the provision of virtual care: adherence to existing standards and regulations, appropriateness, consent, physical examination, patient-reported outcomes, use in addition to in-person visits, and complex comanagement of disease. Conclusion. The best practice statements represent a starting point for advancing virtual care in rheumatology. Future educational efforts to help implement these best practices and research to address identified knowledge gaps are planned

Improving nitrogen cycling in a land surface model (CLM5) to quantify soil N2O, NO, and NH3 emissions from enhanced rock weathering with croplands

Surficial enhanced rock weathering (ERW) is a land-based carbon dioxide removal (CDR) strategy that involves applying crushed silicate rock (e.g., basalt) to agricultural soils. However, unintended biogeochemical interactions with the nitrogen cycle may arise through ERW increasing soil pH as basalt grains undergo dissolution that may reinforce, counteract, or even offset the climate benefits from carbon sequestration. Increases in soil pH could drive changes in the soil emissions of key non-CO2 greenhouse gases, e.g., nitrous oxide (N2O), and trace gases, e.g., nitric oxide (NO) and ammonia (NH3), that affect air quality and crop and human health. We present the development and implementation of a new improved nitrogen cycling scheme for the Community Land Model v5 (CLM5), the land component of the Community Earth System Model, allowing evaluation of ERW effects on soil gas emissions. We base the new parameterizations on datasets derived from soil pH responses of N2O, NO, and NH3 in ERW field trial and mesocosm experiments with crushed basalt. These new capabilities involve the direct implementation of routines within the CLM5 N cycle framework, along with asynchronous coupling of soil pH changes estimated through an ERW model. We successfully validated simulated “control” (i.e., no ERW) seasonal cycles of soil N2O, NO, and NH3 emissions against a wide range of global emission inventories. We benchmark simulated mitigation of soil N2O fluxes in response to ERW against a subset of data from ERW field trials in the US Corn Belt. Using the new scheme, we provide a specific example of the effect of large-scale ERW deployment with croplands on soil nitrogen fluxes across five key regions with high potential for CDR with ERW (North America, Brazil, Europe, India, and China). Across these regions, ERW implementation led to marked reductions in N2O and NO (both 18 %), with moderate increases in NH3 (2 %). While further developments are still required in our implementations when additional ERW data become available, our improved N cycle scheme within CLM5 has utility for investigating the potential of ERW point-source and regional effects of soil N2O, NO, and NH3 fluxes in response to current and future climates. This framework also provides the basis for assessing the implications of ERW for air quality given the role of NO in tropospheric ozone formation, as well as both NO and NH3 in inorganic aerosol formation

Regulation of phosphorylase kinase by low concentrations of Ca ions upon muscle contraction: the connection between metabolism and muscle contraction and the connection between muscle physiology and Ca-dependent signal transduction

It had long been one of the crucial questions in muscle physiology how glycogenolysis is regulated in connection with muscle contraction, when we found the answer to this question in the last half of the 1960s. By that time, the two principal currents of muscle physiology, namely, the metabolic flow starting from glycogen and the mechanisms of muscle contraction, had already been clarified at the molecular level thanks to our senior researchers. Thus, the final question we had to answer was how to connect these two currents. We found that low concentrations of Ca ions (10−7–10−4 M) released from the sarcoplasmic reticulum for the regulation of muscle contraction simultaneously reversibly activate phosphorylase kinase, the enzyme regulating glycogenolysis. Moreover, we found that adenosine 3′,5′-monophosphate (cyclic AMP), which is already known to activate muscle phosphorylase kinase, is not effective in the absence of such concentrations of Ca ions. Thus, cyclic AMP is not effective by itself alone and only modifies the activation process in the presence of Ca ions (at that time, cyclic AMP-dependent protein kinase had not yet been identified). After a while, it turned out that our works have not only provided the solution to the above problem on muscle physiology, but have also been considered as the first report of Ca-dependent protein phosphorylation, which is one of the central problems in current cell biology. Phosphorylase kinase is the first protein kinase to phosphorylate a protein resulting in the change in the function of the phosphorylated protein, as shown by Krebs and Fischer. Our works further showed that this protein kinase is regulated in a Ca-dependent manner. Accordingly, our works introduced the concept of low concentrations of Ca ions, which were first identified as the regulatory substance of muscle contraction, to the vast field of Ca biology including signal transduction

Running the club for love: Challenges for identity, accountability and governance relationships

The current context of State sport governance and funding structures in the United Kingdom continue to challenge national, regional and local bodies and community clubs’ abilities to fulfil ambitions to support participation and competition at all levels. Notwithstanding sport clubs’ laudable intentions to support involvement and encourage participation (often with limited resources, guidance and communication from National Governing Bodies (NGB)), clubs face considerable practical, political and ideological constraints that adversely affect their day-to-day operations and ability to translate sport policy in ‘action’ in meaningful ways. Drawing on data from 21 athletic clubs in England, this paper examines how athletic clubs’ relations with the NGB, UK Athletics (UKA), raise questions about the clubs’ individual and collective identities, agendas, ideals and overall value to its members