188 research outputs found

    Discrimination in an elite labour market? Job placements at the Indian Institute of Management, Ahmedabad

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    Using data on the IIM-Ahmedabad's 2006 batch of MBA graduates, we find that SC/ST (Scheduled Caste or Scheduled Tribe) graduates get significantly lower wages (between 19 and 35 percent depending on the exchange rate used to convert foreign currencies) than those in the general category. This difference disappears once the lower GPAs (Grade Point Averages) of SC/ST candidates are accounted for, suggesting that the large wage difference is due to the weaker (on average) academic performance of SC/ST candidates. Controlling for work experience and GPA, there is no wage penalty to being female. Moreover, unlike the case in US and British labour markets, there is only weak evidence of wage premium to being more attractive, where attractiveness was measured in the standard manner by anonymous ratings of passport-type photographs by twenty raters. The study suggests that in the absence of any serious attempt to equalise school-level opportunities, the current policy of reservations at elite educational institutions will be insufficient to equalise career outcomes even for the minority of SC/ST candidates that can benefit from them.

    Incentives for Developers’ Contributions and Product Performance Metrics in Open Source Development: An Empirical Exploration

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    In open source software development, users rather than paid developers engage in innovation and development without the direct involvement of manufacturers. This paradigm cannot be explained by the two traditional models of innovation, the private investment model and the collective action model. Neither model in itself can explain the phenomenon of the open source model or its success. In order to bridge the gap between existing models and the open source phenomenon, we analyze data from a web survey of 160 open source developers. First, we investigate the motives affecting the individual developer’s contributions by comparing and contrasting the incentives from both the traditional private investment and collective action models. Second, we demonstrate that there is a common ground between the private and collective models where private returns and social considerations can coexist. Third, we explore the effect of incentives on the output of innovation—final product performance. The results show that the motivations for individual developer’s contributions are quite different from the incentives that affect product performance.

    Cytoplasmic Streaming in Drosophila Melanogaster

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    Noncommutative Schwarzschild Black Hole and Area Law

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    Using a graphical analysis, we show that for the horizon radius rh≳4.8ξr_h\gtrsim 4.8\sqrt\theta, the standard semiclassical Bekenstein-Hawking area law for noncommutative Schwarzschild black hole exactly holds for all orders of ξ\theta. We also give the corrections to the area law to get the exact nature of the Bekenstein-Hawking entropy when rh<4.8ξr_h<4.8\sqrt\theta till the extremal point rh=3.0ξr_h=3.0\sqrt{\theta}.Comment: 11 pages, 8 figures, refs. added, minor modifications, to appear in Class. Quant. Gra

    Periodicity staircase in a Fe/Gd magnetic thin film

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    Presence of multiple competing periodicities may result in a system to go through states with modulated periodicities, an example of which is the self-similar staircase-like structure called the Devil's staircase. Herein we report on a novel staircase structure of domain periodicity in an amorphous and achiral Fe/Gd magnetic thin film wherein the reciprocal space wavevector \textbf{Q} due to the ordered stripe domains does not evolve continuously, rather exhibits a staircase structure. Resonant X-ray scattering experiments show jumps in the periodicity of the stripe domains as a function of an external magnetic field. When resolved in components, the step change along Qx_x was found to be an integral multiple of a minimum step height of 7 nm, which resembles closely to the exchange length of the system. Modeling the magnetic texture in the Fe/Gd thin film as an achiral spin arrangement, we have been able to reproduce the steps in the magnetization using a Landau-Lifshitz spin dynamics calculation. Our results indicate that anisotropy and not the dipolar interaction is the dominant cause for the staircase pattern, thereby revealing the effect of achiral magnetism.Comment: 9 pages, 5 figure

    The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation

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    © 2015 The Obesity Society. Objective Chronic, low-grade adipose tissue inflammation associated with adipocyte hypertrophy is an important link in the relationship between obesity and insulin resistance. Although ubiquitin ligases regulate inflammatory processes, the role of these enzymes in metabolically driven adipose tissue inflammation is relatively unexplored. Herein, the effect of the ubiquitin ligase Siah2 on obesity-related adipose tissue inflammation was examined. Methods Wild-type and Siah2KO mice were fed a low- or high-fat diet for 16 weeks. Indirect calorimetry, body composition, and glucose and insulin tolerance were assayed along with glucose and insulin levels. Gene and protein expression, immunohistochemistry, adipocyte size distribution, and lipolysis were also analyzed. Results Enlarged adipocytes in obese Siah2KO mice were not associated with obesity-induced insulin resistance. Proinflammatory gene expression, stress kinase signaling, fibrosis, and crown-like structures were reduced in the Siah2KO adipose tissue, and Siah2KO adipocytes were more responsive to insulin-dependent inhibition of lipolysis. Loss of Siah2 increased expression of PPARγ target genes involved in lipid metabolism and decreased expression of proinflammatory adipokines regulated by PPARγ. Conclusions Siah2 links adipocyte hypertrophy with adipocyte dysfunction and recruitment of proinflammatory immune cells to adipose tissue. Selective regulation of PPARγ activity is a Siah2-mediated mechanism contributing to obesity-induced adipose tissue inflammation

    Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle

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    SummaryFatty acids are the primary fuel source for skeletal muscle during most of our daily activities, and impaired fatty acid oxidation (FAO) is associated with insulin resistance. We have developed a mouse model of impaired FAO by deleting carnitine palmitoyltransferase-1b specifically in skeletal muscle (Cpt1bm−/−). Cpt1bm−/− mice have increased glucose utilization and are resistant to diet-induced obesity. Here, we show that inhibition of mitochondrial FAO induces FGF21 expression specifically in skeletal muscle. The induction of FGF21 in Cpt1b-deficient muscle is dependent on AMPK and Akt1 signaling but independent of the stress signaling pathways. FGF21 appears to act in a paracrine manner to increase glucose uptake under low insulin conditions, but it does not contribute to the resistance to diet-induced obesity

    Antiferromagnetic real-space configuration probed by x-ray orbital angular momentum phase dichroism

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    X-ray beams with orbital angular momentum (OAM) are an up-and-coming tool for x-ray characterization techniques. Beams with OAM have an azimuthally varying phase that leads to a gradient of the light field. New material properties can be probed by utilizing the unique phase structure of an OAM beam. Here, we demonstrate a novel type of phase dichroism in resonant diffraction from an artificial antiferromagnet with a topological defect. The scattered OAM beam has circular dichroism whose sign is coupled to the phase of the beam, which reveals the real-space configuration of the antiferromagnetic ground state. Thermal cycling of the artificial antiferromagnet can change the ground state, as indicated by the changing phase dichroism. These results exemplify the potential of OAM beams to probe matter in a way that is inaccessible using typical x-ray techniques

    Developing Brain Vital Signs: Initial Framework for Monitoring Brain Function Changes over Time

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    Clinical assessment of brain function relies heavily on indirect behavior-based tests. Unfortunately, behavior-based assessments are subjective and therefore susceptible to several confounding factors. Event-related brain potentials (ERPs), derived from electroencephalography (EEG), are often used to provide objective, physiological measures of brain function. Historically, ERPs have been characterized extensively within research settings, with limited but growing clinical applications. Over the past 20 years, we have developed clinical ERP applications for the evaluation of functional status following serious injury and/or disease. This work has identified an important gap: the need for a clinically accessible framework to evaluate ERP measures. Crucially, this enables baseline measures before brain dysfunction occurs, and might enable the routine collection of brain function metrics in the future much like blood pressure measures today. Here, we propose such a framework for extracting specific ERPs as potential “brain vital signs.” This framework enabled the translation/transformation of complex ERP data into accessible metrics of brain function for wider clinical utilization. To formalize the framework, three essential ERPs were selected as initial indicators: (1) the auditory N100 (Auditory sensation); (2) the auditory oddball P300 (Basic attention); and (3) the auditory speech processing N400 (Cognitive processing). First step validation was conducted on healthy younger and older adults (age range: 22–82 years). Results confirmed specific ERPs at the individual level (86.81–98.96%), verified predictable age-related differences (P300 latency delays in older adults, p &lt; 0.05), and demonstrated successful linear transformation into the proposed brain vital sign (BVS) framework (basic attention latency sub-component of BVS framework reflects delays in older adults, p &lt; 0.05). The findings represent an initial critical step in developing, extracting, and characterizing ERPs as vital signs, critical for subsequent evaluation of dysfunction in conditions like concussion and/or dementia
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