MANTLE-CRUST INTERACTION AT THE LATE STAGE OF EVOLUTION OF HERCYNIAN ALTAI COLLISION SYSTEM, WESTERN PART OF CAOB

Altai collision system of Hercynides was formed in Late Paleozoic as a result of oblique collision of Siberian continent and Kazakhstan composed terrane [Vladimirov et al., 2003; 2008; Xiao et al., 2010]. At the late stages of its evolution (time interval from 310–300 to 280–270 Ma) the huge different mafic and felsic magmatism occurred at the territory (Fig. 1) [Vladimirov et al., 2008; Khromykh et al., 2011, 2013, 2014, 2016; Kotler et al., 2015; Sokolova et al., 2016]. It is evident about increased thermal gradient in lithosphere and about significant role of mantle and active manifestation of mantle-crust interactions. Some magmatic complexes may be considered as indicators of mantle-crust interaction processes.Altai collision system of Hercynides was formed in Late Paleozoic as a result of oblique collision of Siberian continent and Kazakhstan composed terrane [Vladimirov et al., 2003; 2008; Xiao et al., 2010]. At the late stages of its evolution (time interval from 310–300 to 280–270 Ma) the huge different mafic and felsic magmatism occurred at the territory (Fig. 1) [Vladimirov et al., 2008; Khromykh et al., 2011, 2013, 2014, 2016; Kotler et al., 2015; Sokolova et al., 2016]. It is evident about increased thermal gradient in lithosphere and about significant role of mantle and active manifestation of mantle-crust interactions. Some magmatic complexes may be considered as indicators of mantle-crust interaction processes

Global fluid phase behavior in binary mixtures of rodlike and platelike molecules

Published versio

Некоторые аспекты генетического контроля биосинтеза антибиотиков у Streptomyces

These work contain a review of basic hypotheses and experimental information in relation to the problem of antibiotic synthesis regulation by the bacteria of the Streptomyces family. Data on cluster organization of antibiotics biosynthesis genes in these microorganisms were generalized. The examples of the positive and negative specific control of antibiotic production genes were resulted. Except for it, proofs that confirm participation of a few genes of more high level in the process of initiation and expression of antibiotics biosynthesis genes also were found. In this connection А-factor role in the mechanism of cascade-organized process of streptomycin biosynthesis control, some other antibiotics and spore determinations is discussed in detail.Проаналізовано основні гіпотези та експериментальні дані, подані у літературі стосовно регуляції синтезу антибіотичних речовин представниками роду Streptomyces. Узагальнено дані про кластерну організацію генів біосинтезу деяких антибіотиків у цих мікроорганізмів. Наведено приклади позитивної та негативної регуляції експресії генів біосинтезу антибіотиків. Крім цього, знайдено докази, що підтверджують участь у процесі ініціації та експресії генів біосинтезу антибіотиків ще кількох генів більш високого рівня. У цьому зв’язку детально розібрано роль А-фактора у механізмі каскадно організованого процесу регуляції біосинтезу стрептоміцину, деяких інших антибіотиків, а також спороутворення. Проаналізовано основні гіпотези та експериментальні дані, подані у літературі стосовно регуляції синтезу антибіотичних речовин представниками роду Streptomyces. Узагальнено дані про кластерну організацію генів біосинтезу деяких антибіотиків у цих мікроорганізмів. Наведено приклади позитивної та негативної регуляції експресії генів біосинтезу антибіотиків. Крім цього, знайдено докази, що підтверджують участь у процесі ініціації та експресії генів біосинтезу антибіотиків ще кількох генів більш високого рівня. У цьому зв’язку детально розібрано роль А-фактора у механізмі каскадно організованого процесу регуляції біосинтезу стрептоміцину, деяких інших антибіотиків, а також спороутворення.

Binase Do Not Change Level of Intracellular RNA in Breast Cancer Cells

© 2017, Springer Science+Business Media, LLC. We analyzed changes of intracellular RNA level in breast cancer cells using BT-20, BT-474, and MCF-7 cell lines. It is the continuation of our former studying the effect of bacterial ribonucleases on physiological and biochemical parameters of breast cancer cells. For the first time, we tested ability of Bacillus pumilus RNase (binase) to effect the level of intracellular RNA in these cells. Differences in total RNA level under of the binase action on the cells of triple negative, triple positive, and double positive breast cancer during 48 h of treatment were not detected. The sensitivity of cells to binase was not associated with a reduction of the intracellular RNA level

Algorithmic approach based on logical qualifiers of subcontractors during creation of large machine-building complexes

The currently stepped price competition stage, in other words, the quality of competition is defined by whether the quality of engineering products depends both on the assembly and on those parts of the product, which is going. The suggested information-analytical tender system, including remote maintenance, connects with the help of web technologies the enterprise financial structure of the workstations operators and authorized persons of contractors located in different geographical areas of the world to form an effective infrastructure for the production, including the incorporation of Russian and foreign small and medium-sized businesses in the technological chain of transnational corporations

The POTENTIAL IMPLEMENTATION OF A FREE TRADE AREA ON A TWO- SIDED AND MANY-SIDED

El artículo está dedicado al análisis de la implementación potencial de las áreas de libre comercio (TLC) sobre una base doble y múltiple y los principales problemas de desarrollo de las relaciones económicas entre la Unión Económica Euroasiática (EAEU) y el República Socialista de Vietnam (la SRV). El análisis del comercio exterior entre países de la EAEU y Vietnam se realiza sobre la base del modelo de gravedad del autor que puede usarse para analizar el desarrollo de las conexiones de comercio exterior entre la EAEU y otros países. Según el modelo de gravedad del autor, se demuestra que el Tratado de Libre Comercio es un instrumento bastante efectivo para las relaciones comerciales de desarrollo entre paísesO artigo é dedicado à análise da potencial implementação de áreas de livre comércio (TLC) em dois lados e em vários lados e os principais problemas de desenvolvimento das relações econômicas entre a União Econômica da Eurásia (EAEU) e a República Socialista do Vietnã (SRV). A análise do comércio exterior entre os países da EAEU e o Vietnã é realizada com base no modelo de gravidade do autor, que pode ser usado para analisar o desenvolvimento de conexões de comércio exterior entre a EAEU e outros países. De acordo com o modelo de gravidade do autor, está provado que o Acordo de Livre Comércio é um instrumento bastante eficaz para o desenvolvimento das relações comerciais entre os países.The article is devoted to the analysis of the potential implementation of free trade areas (the FTA) on a two-sided and many-sided basis and main problems of development the economic relations between the Eurasian Economic Union (the EAEU) and the Socialist Republic of Vietnam (the SRV). The analysis of the foreign trade between countries of the EAEU and Vietnam is fulfilled on the base of author’s gravity model which can be used fo

Psychological and pedagogical support for the social workers professional development

The effectiveness of psychological andpedagogical support is determined by the following factors: self-determination and voluntary participation; activating education results; taking into account and developing social workers’ educational needs; the use of the dichotomic and humanistic approaches; social workers’ selfdetermination; interactive mode of cooperation, democratic style of communicatio

Cyclotron resonant scattering feature simulations. I. Thermally averaged cyclotron scattering cross sections, mean free photon-path tables, and electron momentum sampling

Electron cyclotron resonant scattering features (CRSFs) are observed as absorption-like lines in the spectra of X-ray pulsars. A significant fraction of the computing time for Monte Carlo simulations of these quantum mechanical features is spent on the calculation of the mean free path for each individual photon before scattering, since it involves a complex numerical integration over the scattering cross section and the (thermal) velocity distribution of the scattering electrons. We aim to numerically calculate interpolation tables which can be used in CRSF simulations to sample the mean free path of the scattering photon and the momentum of the scattering electron. The tables also contain all the information required for sampling the scattering electron's final spin. The tables were calculated using an adaptive Simpson integration scheme. The energy and angle grids were refined until a prescribed accuracy is reached. The tables are used by our simulation code to produce artificial CRSF spectra. The electron momenta sampled during these simulations were analyzed and justified using theoretically determined boundaries. We present a complete set of tables suited for mean free path calculations of Monte Carlo simulations of the cyclotron scattering process for conditions expected in typical X-ray pulsar accretion columns (0.01<B/B_{crit}<=0.12, where B_{crit}=4.413x10^{13} G and 3keV<=kT<15keV). The sampling of the tables is chosen such that the results have an estimated relative error of at most 1/15 for all points in the grid. The tables are available online at http://www.sternwarte.uni-erlangen.de/research/cyclo.Comment: A&A, in pres

Microbial risk assessment of drinking water based on hydrodynamic modelling of pathogen concentrations in source water

Norovirus contamination of drinking water sources is an important cause of waterborne disease outbreaks. Knowledge on pathogen concentrations in source water is needed to assess the ability of a drinking water treatment plant (DWTP) to provide safe drinking water. However, pathogen enumeration in source water samples is often not sufficient to describe the source water quality. In this study, the norovirus concentrations were characterised at the contamination source, i.e. in sewage discharges. Then, the transport of norovirus within the water source (the river Gota alv in Sweden) under different loading conditions was simulated using a hydrodynamic model. Based on the estimated concentrations in source water, the required reduction of norovirus at the DWTP was calculated using quantitative microbial risk assessment (QMRA). The required reduction was compared with the estimated treatment performance at the DWTP. The average estimated concentration in source water varied between 4.8 x 10(2) and 7.5 x 10(3) genome equivalents L-1; and the average required reduction by treatment was between 7.6 and 8.8 Log(10). The treatment performance at the DWTP was estimated to be adequate to deal with all tested loading conditions, but was heavily dependent on chlorine disinfection, with the risk of poor reduction by conventional treatment and slow sand filtration. To our knowledge, this is the first article to employ discharge-based QMRA, combined with hydrodynamic modelling, in the context of drinking water. (C) 2015 Elsevier B.V. All rights reserved