Correlation effects in Ni 3d states of LaNiPO

The electronic structure of the new superconducting material LaNiPO experimentally probed by soft X-ray spectroscopy and theoretically calculated by the combination of local density approximation with Dynamical Mean-Field Theory (LDA+DMFT) are compared herein. We have measured the Ni L2,3 X-ray emission (XES) and absorption (XAS) spectra which probe the occupied and unoccupied the Ni 3d states, respectively. In LaNiPO, the Ni 3d states are strongly renormalized by dynamical correlations and shifted about 1.5 eV lower in the valence band than the corresponding Fe 3d states in LaFeAsO. We further obtain a lower Hubbard band at -9 eV below the Fermi level in LaNiPO which bears striking resemblance to the lower Hubbard band in the correlated oxide NiO, while no such band is observed in LaFeAsO. These results are also supported by the intensity ratio between the transition metal L2 and L3 bands measured experimentally to be higher in LaNiPO than in LaFeAsO, indicating the presence of the stronger electron correlations in the Ni 3d states in LaNiPO in comparison with the Fe 3d states in LaFeAsO. These findings are in accordance with resonantly excited transition metal L3 X-ray emission spectra which probe occupied metal 3d-states and show the appearance of the lower Hubbard band in LaNiPO and NiO and its absence in LaFeAsO.Comment: 6 pages, 5 figure

Coulomb correlation effects in LaOFeAs: LDA+DMFT(QMC) study

Effects of Coulomb correlation on LaOFeAs electronic structure have been investigated by LDA+DMFT(QMC) method. The calculation results show that LaOFeAs is in the regime of intermediate correlation strength with significant part of the spectral density moved from the Fermi energy to Hubbard bands. However the system is not on the edge of metal insulator-transition because increase of the Coulomb interaction parameter value from $U$=4.0 eV to $U$=5.0 eV did not result in insulator state. Correlations affect different d-orbitals not in the same way. $t_{2g}$ states ($xz,yz$ and $x^2-y^2$ orbitals) have higher energy due to crystal filed splitting and are nearly half-filled. Their spectral functions have pseudogap with Fermi energy position on the higher sub-band slope. Lower energy $e_g$ set of d-orbitals ($3z^2-r^2$ and $xy$) have significantly larger occupancy values with typically metallic spectral functions.Comment: 4 pages, 4 figure

Strategy and tactics of immunization of children of the first year of life against tuberculosis: unresolved questions

In Sverdlovsk region from 1998 for 2014 for the purpose of improvement of specific prevention of ТВ of newborn children the assessment of efficiency of single primary immunization now in use of children of the first year of life against tuberculosis (ТВ) is carried out. The condition of specific immunization against ТВ of 725370 newborn children up to 3 months of life and 73814 children of the first year of life, results of a tuberkulinodiagnostika of 720708 children at the age of 1 year, including 25795 children who received repeated immunization on registration forms of account 63, 5 and 6 in the monthly and annual mode is studied. The annual planned tuberkulinodiagnostikta was carried out with allergen tubercular cleaned liquid in standard cultivation (tuberkuliny) 2 THOSE for identification of the children who do not have the immune answer (negative results) and simultaneous identification for the first time of the infected ТВ. The children who did not create specific immunity have high risk of infection of ТВ in the course of natural 'proepidemichivaniye' as 96.7% of number of the general incidence of ТВ, and 99.8% of mortality of number of the general mortality of ТВ were the share of adult population.В Свердловской области за период с 1998 г. по 2014 г. с целью совершенствования специфической профилактики туберкулеза (далее - ТБ) новорожденных детей проведена оценка эффективности используемой в настоящее время однократной первичной вакцинации детей первого года жизни против туберкулеза (ТБ). Изучено состояние специфической иммунизации против ТБ у 725370 новорожденных детей до 3 месяцев жизни и 73814 детей первого года жизни, результаты туберкулинодиагностики 720708 детей в возрасте 1 года, в том числе 25795 детей, получивших повторную иммунизацию по учетно-отчетным формам №№ 63,5 и 6 ФСН в ежемесячном и годовом режимах. Ежегодная плановая туберкулино-диагностика проводилась с аллергеном туберкулезным очищенным жидким в стандартном разведении (туберкулином) 2 ТЕ для выявления детей, не имеющих иммунного ответа (отрицательные результаты) и одновременного выявления впервые инфицированных ТБ. Установлено, что в возрасте одного года около 25-26 % детей имеют отрицательный результат реакции Манту после одной прививки, что свидетельствует об отсутствии специфического иммунитета к ТБ. Эти дети нуждаются в персональной корректировке иммунитета, т.е. в дополнительной иммунизации. Не сформировавшие специфический иммунитет дети имеют высокий риск заражения ТБ в процессе естественного «проэпидемичивания» поскольку на взрослое население приходилось 96,7 % от числа общей заболеваемости ТБ, и 99,8 % смертности от числа общей смертности от ТБ

Synthesis, X-ray crystal structure and antimycobacterial activity of enantiomerically pure 1-ethyl-2,3-dicyano-5-(het)aryl-6-hetaryl-1,6- dihydropyrazines

The Petasis reaction of 6-alkoxy adducts of 1-alkyl-2,3-dicyano-5- arylpyrazinium salts with aromatic boronic acids, such as 2-thienylboronic, 2-furanylboronic and 3-thienylboronic acids, or their benzo analogs in dichloromethane proceeds smoothly at room temperature with the formation of the corresponding 5-aryl-6-hetaryl substituted 1,6-dihydropyrazine derivatives. All dihydropyrazines were separated as pure enantiomers by chiral HPLC, and their absolute configurations for each pair of enantiomers have been determined by X-ray analysis. Individual enantiomers were screened in vitro for their antimycobacterial activities against Mycobacterium tuberculosis H37Rv, avium, terrae and extensively drug-resistant and multi-drug-resistant strains isolated from tuberculosis patients in Ural region (Russia). It has been shown that several compounds exhibit a good level of antituberculosis activity compared to the reference drugs. © ARKAT-USA, Inc

Motivation of students to use remote educational technologies in training in "phthisiology" discipline during implementation of basic educational programs of specialization

Цель работы – изучение отношения студентов к применению ДОТ при обучении дисциплине фтизиатрия в ходе реализации основных образовательных программ в ФГБОУ ВО Уральский государственный медицинский университет Минздрава России (УГМУ)

Electronic structure and possible pseudogap behavior in iron based superconductors

Starting from the simplified analytic model of electronic spectrum of iron - pnictogen (chalcogen) high - temperature superconductors close to the Fermi level, we discuss the influence of antiferromagneting (AFM)scattering both for stoichiometric case and the region of possible short - range order AFM fluctuations in doped compounds. Qualitative picture of the evolution of electronic spectrum and Fermi surfaces (FS) for different dopings is presented, with the aim of comparison with existing and future ARPES experiments. Both electron and hole dopings are considered and possible pseudogap behavior connected with partial FS "destruction" is demonstrated, explaining some recent experiments.Comment: 5 pages, 4 figures, published versio

Microwave-Assisted synthesis and evaluation of antibacterial activity of novel 6-fluoroaryl-[1,2,4]triazolo[1,5-A]pyrimidines

A series of 6-fluoroaryl substituted [1,2,4]triazolo[1,5-A]pyrimidines have been synthesized by using the microwave-Assisted Suzuki cross-coupling reaction from readily available 6-bromo-[1,2,4]triazolo[1,5-A]pyrimidine. The antimicrobial activity of new compounds has been evaluated in vitro against Mycobacterium tuberculosis H37Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria. © ARKAT-USA, Inc

Современные подходы к поиску активных препаратов, схем и режимов химиотерапии туберкулеза

The article analyzes scientific publications (37 articles) devoted to phthisiology, clinical pharmacology of antimicrobial agents, laboratory methods for evaluating the effectiveness and safety of various regimens of tuberculosis chemotherapy caused by resistant strains of M. tuberculosis.It tells about prospects for expanding the line of antimicrobial agents for treatment of tuberculosis caused by resistant strains of M. tuberculosis, new approaches to the study and evaluation of the effectiveness of the drug at the stage of preclinical trials using the in vitro HFS-TV model.Проведен анализ научных публикаций (37 источников) в области фтизиатрии, клинической фармакологии антимикробных препаратов, лабораторных методов оценки эффективности и безопасности различных схем и режимов химиотерапии туберкулеза, обусловленного резистентными штаммами M. tuberculosis.Представлена информация о перспективах расширения линейки антимикробных препаратов для лечения туберкулеза, обусловленного резистентными штаммами M. tuberculosis, новых подходах к изучению и оценке эффективности лекарственных воздействий на этапе доклинических исследований с применением модели in vitro HFS-ТВ

Scaling limit of virtual states of triatomic systems

For a system with three identical atoms, the dependence of the $s-$wave virtual state energy on the weakly bound dimer and trimer binding energies is calculated in a form of a universal scaling function. The scaling function is obtained from a renormalizable three-body model with a pairwise Dirac-delta interaction. It was also discussed the threshold condition for the appearance of the trimer virtual state.Comment: 9 pages, 3 figure

Effect of the tetrahedral distortion on the electronic properties of iron-pnictides

We study the dependence of the electronic structure of iron pnictides on the angle formed by the arsenic-iron bonds. Within a Slater-Koster tight binding model which captures the correct symmetry properties of the bands, we show that the density of states and the band structure are sensitive to the distortion of the tetrahedral environment of the iron atoms. This sensitivity is extremely strong in a two-orbital (d_xz, d_yz) model due to the formation of a flat band around the Fermi level. Inclusion of the d_xy orbital destroys the flat band while keeping a considerable angle dependence in the band structure.Comment: 5 pages, including 5 figures. Fig. 5 replaced. Minor changes in the tex