Computational modeling of acute myocardial infarction

This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial infarction, commonly known as heart attack, is caused by reduced blood supply and damages the heart muscle because of a lack of oxygen. Myocardial infarction initiates a cascade of biochemical and mechanical events. In the early stages, cardiomyocytes death, wall thinning, collagen degradation, and ventricular dilation are the immediate consequences of myocardial infarction. In the later stages, collagenous scar formation in the infarcted zone and hypertrophy of the non-infarcted zone are auto-regulatory mechanisms to partly correct for these events. Here we propose a computational model for the short-term adaptation after myocardial infarction using the continuum theory of multiplicative growth. Our model captures the effects of cell death initiating wall thinning, and collagen degradation initiating ventricular dilation. Our simulations agree well with clinical observations in early myocardial infarction. They represent a first step toward simulating the progression of myocardial infarction with the ultimate goal to predict the propensity toward heart failure as a function of infarct intensity, location, and size.Peer ReviewedPostprint (author's final draft

Small Angular Scale Simulations of the Microwave Sky

We describe and compare two types of microwave sky simulations which are good for small angular scales. The first type uses expansions in spherical harmonics, and the second one is based on plane waves and the Fast Fourier Transform. The angular power spectrum is extracted from maps corresponding to both types of simulations, and the resulting spectra are appropriately compared. In this way, the features and usefulness of Fourier simulations are pointed out. For $\ell \geq 100$, all the simulations lead to similar accuracies; however, the CPU cost of Fourier simulations is $\sim 10$ times smaller than that for spherical harmonic simulations. For $\ell \leq 100$, the simulations based on spherical harmonics seem to be preferable.Comment: 16 pages (LATEX), 2 postcript figures. Accepted in Ap

Symplectic matrices with predetermined left eigenvalues

We prove that given four arbitrary quaternion numbers of norm 1 there always exists a $2\times 2$ symplectic matrix for which those numbers are left eigenvalues. The proof is constructive. An application to the LS category of Lie groups is given.Comment: 7 page

Spherically Symmetric Solutions in M\o ller's Tetrad Theory of Gravitation

The general solution of M\o ller's field equations in case of spherical symmetry is derived. The previously obtained solutions are verified as special cases of the general solution.Comment: LaTeX2e with AMS-LaTeX 1.2, 8 page