Fate of 2D Kinetic Ising Ferromagnets and Critical Percolation Crossing Probabilities

We present evidence for a deep connection between the zero-temperature coarsening of the two-dimensional kinetic Ising model (KIM) and critical continuum percolation. In addition to reaching the ground state, the KIM can also fall into a variety of topologically distinct metastable stripe states. The probability to reach a stripe state that winds a times horizontally and b times vertically on a square lattice with periodic boundary conditions equals the corresponding exactly-solved critical percolation crossing probability P_{a,b} for a spanning path with winding numbers a and b.Comment: 4 pages, 4 figure, 2-column revtex4 format. Revision contains material about the TDGL and is nearly identical to the final published versio

1H-Tetrazol-5-amine and 1,3-thiazolidin-4-one derivatives containing 3-(trifluoromethyl)phenyl scaffold: Synthesis, cytotoxic and anti-HIV studies

On the basis of recently reported biologically active 3-(trifluoromethyl)phenylthioureas, a series of diaryl derivatives incorporating 1H-tetrazol-5-yl (1aâ\u80\u9311a, 1aâ\u80\u99â\u80\u9311aâ\u80\u99) and 1,3-thiazolidin-4-one (1bâ\u80\u9311b) scaffolds were synthesized. The synthesis pathway was confirmed by an X-ray crystallographic studies of 3aâ\u80\u99, 6a, 8a, 6b and 8b. The cytotoxicity against MT-4 cells and anti-HIV properties of new derivatives were evaluated. As compared to initial thiourea connections, the cyclisation reduced the cytotoxicity of compounds by 2â\u80\u9315 times. The most promising N-(4-nitrophenyl)-1H-tetrazol-5-amine 7a was found to be more active than the origin thiourea. Its cytotoxicity was evaluated on A549, HTB-140 and HaCaT cell lines using MTT assay. The compound shows significant influence on cancer, but not on normal cells. Obtained results can provide some constructive data for further designing of novel family of potentially bioactive analogs