1,461 research outputs found

    Using Cognitive Assessment Testing to Evaluate and Improve a University Program in Communication Studies

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    This article attempts to demonstrate how cognitive assessment may be used to empower both faculty and students by offering pedagogical and administrative strategies that enhance student learning in the U.S. The faculty limited its cognitive test, the Pre-Communication Assessment Measure to the four competencies--critical thinking, interpersonal, decision-making and theoretical competencies--common to two of five required courses. The components of the cognitive test are: critical thinking competence, interpersonal competence, decision-making competence and theoretical competence

    Guide for the identification of archaeological sea sturgeon (<i>Acipenser sturio</i> and <i>A. oxyrinchus</i>) remains

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    Remains of sturgeons (Acipenser sturio and A. oxyrinchus) are regularly found on western European archaeological sites. The identification of these isolated bones should ideally be carried out with the aid of a comparative skeletal collection, consisting of modern specimens of different sizes. Because such reference material of sea sturgeons (A. sturio and A. oxyrinchus) is relatively rare and dispersed over many different museums and institutes, a practical guide is presented here as an aid to the identification of the most commonly found archaeological sturgeon remains. This guide, which is based on observations made on 64 individuals housed in 13 different natural history collections, should allow identifying most archaeological sturgeon remains from western European sites. Presented are the morphological characteristics of the bones of the skull roof and circumorbital region (posttemporal, dermopterotic, parietal, frontal, dermosphenotic, postorbital, jugal and supraorbital), bones of the braincase (parasphenoid), opercular series (subopercle and branchiostegals), the palatoquadrate and associated bones and lower jaw (palatopterygoid, dermopalatine and dentary), the hyoid and gill arches with the hyomandibula, the isolated skeletal elements from the pectoral girdle (clavicle, cleithrum and supracleithrum), the bones of the fin and fin supports (pectoral fin spine, fin rays and fulcra) and the dorsal, ventral, lateral and accessory scutes. For each element, descriptions and pictures are provided of modern and archaeological specimens. Regression equations allowing fish length reconstructions on the basis of single bone measurements are given for 14 elements and the scutes. Finally, criteria for species identification are provided. In the case of the dentary, dermopalatine and palatopterygoid, these are differences in shape of the skeletal elements, whereas for the dermal bones the external surface pattern is diagnostic when reconstructed fish length is over one meter

    Properties of the separated catalytic and regulatory units of brain adenylate cyclase.

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    In-line monitoring and control of rheological properties through data-driven ultrasound soft-sensors

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    The use of continuous processing is replacing batch modes because of their capabilities to address issues of agility, flexibility, cost, and robustness. Continuous processes can be operated at more extreme conditions, resulting in higher speed and efficiency. The issue when using a continuous process is to maintain the satisfaction of quality indices even in the presence of perturbations. For this reason, it is important to evaluate in-line key performance indicators. Rheology is a critical parameter when dealing with the production of complex fluids obtained by mixing and filling. In this work, a tomographic ultrasonic velocity meter is applied to obtain the rheological curve of a non-Newtonian fluid. Raw ultrasound signals are processed using a data-driven approach based on principal component analysis (PCA) and feedforward neural networks (FNN). The obtained sensor has been associated with a data-driven decision support system for conducting the process

    Sulfaresiduen in boerderijmelk

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    Een tussenverslag van de onderzoekresultaten tot nu toe om te komen tot de gewenste onderzoekmethode. Uitgevoerd werden een drietal ringonderzoeken met de Melkcontrolestations en een Keuringsdienst van Waren en een vervolgonderzoek met een Melkcontrolestation en een Keuringsdienst van Waren

    Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands

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    AbstractWe have explored the possibilities of using human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) as a single immunoglobulin fold-based scaffold for the generation of novel binding ligands. To obtain a suitable protein library selection system, the extracellular domain of CTLA-4 was first displayed on the surface of a filamentous phage as a fusion product of the phage coat protein p3. CTLA-4 was shown to be functionally intact by binding to its natural ligands B7-1 (CD80) and B7-2 (CD86) both in vitro and in situ. Secondly, the complementarity determining region 3 (CDR3) loop of the CTLA-4 extracellular domain was evaluated as a permissive site. We replaced the nine amino acid CDR3-like loop of CTLA-4 with the sequence XXX-RGD-XXX (where X represents any amino acid). Using phage display we selected several CTLA-4-based variants capable of binding to human αvβ3 integrin, one of which showed binding to integrins in situ. To explore the construction of bispecific molecules we also evaluated one other potential permissive site diametrically opposite the natural CDR-like loops, which was found to be tolerant of peptide insertion. Our data suggest that CTLA-4 is a suitable human scaffold for engineering single-domain molecules with one or possibly more binding specificities
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