196 research outputs found
Integrating network topology metrics into studies of catchment-level effects on river characteristics
The spatial arrangement of the river network is a fundamental
characteristic of the catchment, acting as a conduit between catchment-level
effects and reach morphology and ecology. Yet river network structure is
often simplified to reflect an upstream-to-downstream gradient of river
characteristics, commonly represented by stream order. The aim of this study
is to quantify network topological structure using two network density
metrics – one that represents network density over distance and the other
over elevation – that can easily be extracted from digital elevation models
and so may be applied to any catchment across the globe. These metrics should
better account for the multi-dimensional nature of the catchment than stream
order and be functionally applicable across geomorphological, hydrological
and ecological attributes of the catchment. The functional utility of the
metrics is assessed by appropriating monitoring data collected for regulatory
compliance to explore patterns of river characteristics in relation to
network topology. This method is applied to four comparatively low-energy,
anthropogenically modified catchments in the UK using river characteristics
derived from England's River Habitat Survey database. The patterns in river
characteristics explained by network density metrics are compared to stream
order as a standard measure of topology. The results indicate that the
network density metrics offer a richer and functionally more relevant
description of network topology than stream order, highlighting differences
in the density and spatial arrangement of each catchment's internal network
structure. Correlations between the network density metrics and river
characteristics show that habitat quality score consistently increases with
network density in all catchments as hypothesized.
For other measures of river character – modification score, flow-type speed and sediment size – there are varying
responses in different catchments to the two network density metrics. There
are few significant correlations between stream order and the river
characteristics, highlighting the limitations of stream order in accounting
for network topology. Overall, the results suggest that network density
metrics are more powerful measures which conceptually and functionally
provide an improved method of accounting for the impacts of network topology
on the fluvial system.</p
Probing the Galactic Bulge with deep Adaptive Optics imaging: the age of NGC 6440
We present first results of a pilot project aimed at exploiting the
potentiality of ground based adaptive optics imaging in the near infrared to
determine the age of stellar clusters in the Galactic Bulge. We have used a
combination of high resolution adaptive optics (ESO-VLT NAOS-CONICA) and
wide-field (ESO-NTT-SOFI) photometry of the metal rich globular cluster NGC
6440 located towards the inner Bulge, to compute a deep color magnitude diagram
from the tip of the Red Giant Branch down to J~22$, two magnitudes below the
Main Sequence Turn Off (TO). The magnitude difference between the TO level and
the red Horizontal Branch has been used as an age indicator. It is the first
time that such a measurement for a bulge globular cluster has been obtained
with a ground based telescope. From a direct comparison with 47 Tuc and with a
set of theoretical isochrones, we concluded that NGC 6440 is old and likely
coeval to 47 Tuc. This result adds a new evidence that the Galactic Bulge is ~2
Gyr younger at most than the pristine, metal poor population of the Galactic
Halo
Analysis of Mutant Platelet-derived Growth Factor Receptors Expressed in PC12 Cells Identifies Signals Governing Sodium Channel Induction during Neuronal Differentiation.
The mechanisms governing neuronal differentiation, including the signals underlying the induction of voltage-dependent sodium (Na+) channel expression by neurotrophic factors, which occurs independent of Ras activity, are not well understood. Therefore, Na+ channel induction was analyzed in sublines of PC12 cells stably expressing platelet-derived growth factor (PDGF) beta receptors with mutations that eliminate activation of specific signalling molecules. Mutations eliminating activation of phosphatidylinositol 3-kinase (PI3K), phospholipase C gamma (PLC gamma), the GTPase-activating protein (GAP), and Syp phosphatase failed to diminish the induction of type II Na+ channel alpha-subunit mRNA and functional Na+ channel expression by PDGF, as determined by RNase protection assays and whole-cell patch clamp recording. However, mutation of juxtamembrane tyrosines that bind members of the Src family of kinases upon receptor activation inhibited the induction of functional Na+ channels while leaving the induction of type II alpha-subunit mRNA intact. Mutation of juxtamembrane tyrosines in combination with mutations eliminating activation of PI3K, PLC gamma, GAP, and Syp abolished the induction of type II alpha-subunit mRNA, suggesting that at least partially redundant signaling mechanisms mediate this induction. The differential effects of the receptor mutations on Na+ channel expression did not reflect global changes in receptor signaling capabilities, as in all of the mutant receptors analyzed, the induction of c-fos and transin mRNAs still occurred. The results reveal an important role for the Src family in the induction of Na+ channel expression and highlight the multiplicity and combinatorial nature of the signaling mechanisms governing neuronal differentiation
High resolution near-IR spectra of NGC 6624 and NGC 6569
We present the first abundances analysis based on high-resolution infrared
(IR) echelle spectra of NGC 6569 and NGC 6624, two moderately reddened globular
clusters located in the outer bulge of the Galaxy. We find
[Fe/H]=-0.790.02 dex and [Fe/H]=-0.690.02 dex for NGC 6569 and NGC
6624, respectively and an average -elements enhancement of
+0.430.02 dex and +0.390.02 dex, consistent with previous
measurements on other metal-rich Bulge clusters. We measure accurate radial
velocities of and
and velocity dispersions of and for NGC 6569 and NGC 6624, respectively. Finally, we find very low
isotopics ratio (7 in NGC 6624 and 5 in NGC
6569), confirming the presence extra-mixing mechanisms during the red giant
branch evolution phase.Comment: 7 pages, 3 figures, accepted for publication on MNRA
XO-2b: Transiting Hot Jupiter in a Metal-rich Common Proper Motion Binary
We report on a V=11.2 early K dwarf, XO-2 (GSC 03413-00005), that hosts a
Rp=0.98+0.03/-0.01 Rjup, Mp=0.57+/-0.06 Mjup transiting extrasolar planet,
XO-2b, with an orbital period of 2.615857+/-0.000005 days. XO-2 has high
metallicity, [Fe/H]=0.45+/-0.02, high proper motion, mu_tot=157 mas/yr, and has
a common proper motion stellar companion with 31" separation. The two stars are
nearly identical twins, with very similar spectra and apparent magnitudes. Due
to the high metallicity, these early K dwarf stars have a mass and radius close
to solar, Ms=0.98+/-0.02 Msolar and Rs=0.97+0.02/-0.01 Rsolar. The high proper
motion of XO-2 results from an eccentric orbit (Galactic pericenter, Rper<4
kpc) well confined to the Galactic disk (Zmax~100 pc). In addition, the phase
space position of XO-2 is near the Hercules dynamical stream, which points to
an origin of XO-2 in the metal-rich, inner Thin Disk and subsequent dynamical
scattering into the solar neighborhood. We describe an efficient Markov Chain
Monte Carlo algorithm for calculating the Bayesian posterior probability of the
system parameters from a transit light curve.Comment: 14 pages, 10 Figures, Accepted in ApJ. Negligible changes to XO-2
system properties. Removed Chi^2 light curve analysis section, and simplified
MCMC light curve analysis discussio
XO-3b: A Massive Planet in an Eccentric Orbit Transiting an F5V Star
We report the discovery of a massive (Mpsini = 13.02 +/- 0.64 Mjup; total
mass 13.25 +/- 0.64 Mjup), large (1.95 +/- 0.16 Rjup) planet in a transiting,
eccentric orbit (e = 0.260 +/- 0.017) around a 10th magnitude F5V star in the
constellation Camelopardalis. We designate the planet XO-3b, and the star XO-3,
also known as GSC 03727-01064. The orbital period of XO-3b is 3.1915426 +/-
0.00014 days. XO-3 lacks a trigonometric distance; we estimate its distance to
be 260 +/- 23 pc. The radius of XO-3 is 2.13 +/- 0.21 Rsun, its mass is 1.41
+/- 0.08 Msun, its vsini = 18.54 +/- 0.17 km/s, and its metallicity is [Fe/H] =
-0.177 +/- 0.027. This system is unusual for a number of reasons. XO-3b is one
of the most massive planets discovered around any star for which the orbital
period is less than 10 days. The mass is near the deuterium burning limit of 13
Mjup, which is a proposed boundary between planets and brown dwarfs. Although
Burrows et al. (2001) propose that formation in a disk or formation in the
interstellar medium in a manner similar to stars is a more logical way to
differentiate planets and brown dwarfs, our current observations are not
adequate to address this distinction. XO-3b is also unusual in that its
eccentricity is large given its relatively short orbital period. Both the
planetary radius and the inclination are functions of the spectroscopically
determined stellar radius. Analysis of the transit light curve of XO-3b
suggests that the spectroscopically derived parameters may be over estimated.
Though relatively noisy, the light curves favor a smaller radius in order to
better match the steepness of the ingress and egress. The light curve fits
imply a planetary radius of 1.25 +/- 0.15 Rjup, which would correspond to a
mass of 12.03 +/- 0.46 Mjup.Comment: 26 pages, 10 figures. Accepted by ApJ. Current version has several
small corrections as a result of a bug in the fitting softwar
A Transiting Planet of a Sun-like Star
A planet transits an 11th magnitude, G1V star in the constellation Corona
Borealis. We designate the planet XO-1b, and the star, XO-1, also known as GSC
02041-01657. XO-1 lacks a trigonometric distance; we estimate it to be 200+-20
pc. Of the ten stars currently known to host extrasolar transiting planets, the
star XO-1 is the most similar to the Sun in its physical characteristics: its
radius is 1.0+-0.08 R_Sun, its mass is 1.0+-0.03 M_Sun, V sini < 3 km/s, and
its metallicity [Fe/H] is 0.015+-0.04. The orbital period of the planet XO-1b
is 3.941534+-0.000027 days, one of the longer ones known. The planetary mass is
0.90+-0.07 M_Jupiter, which is marginally larger than that of other transiting
planets with periods between 3 and 4 days. Both the planetary radius and the
inclination are functions of the spectroscopically determined stellar radius.
If the stellar radius is 1.0+-0.08 R_Sun, then the planetary radius is
1.30+-0.11 R_Jupiter and the inclination of the orbit is 87.7+-1.2 degrees. We
have demonstrated a productive international collaboration between professional
and amateur astronomers that was important to distinguishing this planet from
many other similar candidates.Comment: 31 pages, 9 figures, accepted for part 1 of Ap
Jnk2 Effects on Tumor Development, Genetic Instability and Replicative Stress in an Oncogene-Driven Mouse Mammary Tumor Model
Oncogenes induce cell proliferation leading to replicative stress, DNA damage and genomic instability. A wide variety of cellular stresses activate c-Jun N-terminal kinase (JNK) proteins, but few studies have directly addressed the roles of JNK isoforms in tumor development. Herein, we show that jnk2 knockout mice expressing the Polyoma Middle T Antigen transgene developed mammary tumors earlier and experienced higher tumor multiplicity compared to jnk2 wildtype mice. Lack of jnk2 expression was associated with higher tumor aneuploidy and reduced DNA damage response, as marked by fewer pH2AX and 53BP1 nuclear foci. Comparative genomic hybridization further confirmed increased genomic instability in PyV MT/jnk2−/− tumors. In vitro, PyV MT/jnk2−/− cells underwent replicative stress and cell death as evidenced by lower BrdU incorporation, and sustained chromatin licensing and DNA replication factor 1 (CDT1) and p21Waf1 protein expression, and phosphorylation of Chk1 after serum stimulation, but this response was not associated with phosphorylation of p53 Ser15. Adenoviral overexpression of CDT1 led to similar differences between jnk2 wildtype and knockout cells. In normal mammary cells undergoing UV induced single stranded DNA breaks, JNK2 localized to RPA (Replication Protein A) coated strands indicating that JNK2 responds early to single stranded DNA damage and is critical for subsequent recruitment of DNA repair proteins. Together, these data support that JNK2 prevents replicative stress by coordinating cell cycle progression and DNA damage repair mechanisms
Ultra-Luminous Supernovae as a New Probe of the Interstellar Medium in Distant Galaxies
We present the Pan-STARRS1 discovery and light curves, and follow-up MMT and
Gemini spectroscopy of an ultra-luminous supernova (ULSN; dubbed PS1-11bam) at
a redshift of z=1.566 with a peak brightness of M_UV=-22.3 mag. PS1-11bam is
one of the highest redshift spectroscopically-confirmed SNe known to date. The
spectrum is characterized by broad absorption features typical of previous
ULSNe (e.g., CII, SiIII), and by strong and narrow MgII and FeII absorption
lines from the interstellar medium (ISM) of the host galaxy, confirmed by an
[OII]3727 emission line at the same redshift. The equivalent widths of the
FeII2600 and MgII2803 lines are in the top quartile of the quasar intervening
absorption system distribution, but are weaker than those of gamma-ray burst
intrinsic absorbers (i.e., GRB host galaxies). We also detect the host galaxy
in pre-explosion Pan-STARRS1 data and find that its UV spectral energy
distribution is best fit with a young stellar population age of tau~15-45 Myr
and a stellar mass of M \sim (1.1-2.6)x10^9 M_sun (for Z=0.05-1 Z_sun). The
star formation rate inferred from the UV continuum and [OII]3727 emission line
is ~10 M_sun/yr, higher than in any previous ULSN host. PS1-11bam provides the
first direct demonstration that ULSNe can serve as probes of the interstellar
medium in distant galaxies. At the present, the depth and red sensitivity of
PS1 are uniquely suited to finding such events at cosmologically interesting
redshifts (z~1-2); the future combination of LSST and 30-m class telescopes
promises to extend this technique to z~4.Comment: Submitted to ApJL; 9 pages; 4 figures; 1 tabl
SN 2009kf : a UV bright type IIP supernova discovered with Pan-STARRS 1 and GALEX
We present photometric and spectroscopic observations of a luminous type IIP
Supernova 2009kf discovered by the Pan-STARRS 1 (PS1) survey and detected also
by GALEX. The SN shows a plateau in its optical and bolometric light curves,
lasting approximately 70 days in the rest frame, with absolute magnitude of M_V
= -18.4 mag. The P-Cygni profiles of hydrogen indicate expansion velocities of
9000km/s at 61 days after discovery which is extremely high for a type IIP SN.
SN 2009kf is also remarkably bright in the near-ultraviolet (NUV) and shows a
slow evolution 10-20 days after optical discovery. The NUV and optical
luminosity at these epochs can be modelled with a black-body with a hot
effective temperature (T ~16,000 K) and a large radius (R ~1x10^{15} cm). The
bright bolometric and NUV luminosity, the lightcurve peak and plateau duration,
the high velocities and temperatures suggest that 2009kf is a type IIP SN
powered by a larger than normal explosion energy. Recently discovered high-z
SNe (0.7 < z < 2.3) have been assumed to be IIn SNe, with the bright UV
luminosities due to the interaction of SN ejecta with a dense circumstellar
medium (CSM). UV bright SNe similar to SN 2009kf could also account for these
high-z events, and its absolute magnitude M_NUV = -21.5 +/- 0.5 mag suggests
such SNe could be discovered out to z ~2.5 in the PS1 survey.Comment: Accepted for publication in APJ
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