1,341 research outputs found
Enabling EASEY deployment of containerized applications for future HPC systems
The upcoming exascale era will push the changes in computing architecture
from classical CPU-based systems in hybrid GPU-heavy systems with much higher
levels of complexity. While such clusters are expected to improve the
performance of certain optimized HPC applications, it will also increase the
difficulties for those users who have yet to adapt their codes or are starting
from scratch with new programming paradigms. Since there are still no
comprehensive automatic assistance mechanisms to enhance application
performance on such systems, we are proposing a support framework for future
HPC architectures, called EASEY (Enable exASclae for EverYone). The solution
builds on a layered software architecture, which offers different mechanisms on
each layer for different tasks of tuning. This enables users to adjust the
parameters on each of the layers, thereby enhancing specific characteristics of
their codes. We introduce the framework with a Charliecloud-based solution,
showcasing the LULESH benchmark on the upper layers of our framework. Our
approach can automatically deploy optimized container computations with
negligible overhead and at the same time reduce the time a scientist needs to
spent on manual job submission configurations.Comment: International Conference on Computational Science ICCS2020, 13 page
âAftershock Faultsâ and What They Could Mean for Seismic Hazard Assessment
We study stressâloading mechanisms for the California faults used in rupture forecasts. Stress accumulation drives earthquakes, and that accumulation mechanism governs recurrence. Most moment release in California occurs because of relative motion between the Pacific plate and the Sierra Nevada block; we calculate relative motion directions at fault centers and compare with fault displacement directions. Dot products between these vectors reveal that some displacement directions are poorly aligned with plate motions. We displace a 3D finiteâelement model according to relative motions and resolve stress tensors onto defined fault surfaces, which reveal that poorly aligned faults receive no tectonic loading. Because these faults are known to be active, we search for other loading mechanisms. We find that nearly all faults with no tectonic loading show increase in stress caused by slip on the San Andreas fault, according to an elastic dislocation model. Globally, faults that receive a sudden stress change respond with triggered earthquakes that obey an Omori law rate decay with time. We therefore term this class of faults as âaftershock faults.â These faults release âŒ4% of the moment release in California, have âŒ0.1%â5% probability of M 6.7 earthquakes in 30 yr, and have a 0.001%â1% 30 yr M 7.7 probability range
Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process
© The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology of the Cell 26 (2015): 887-900, doi:10.1091/mbc.E14-07-1244.Recent studies have investigated the dendritic actin cytoskeleton of the cell edge's lamellipodial (LP) region by experimentally decreasing the activity of the actin filament nucleator and branch former, the Arp2/3 complex. Here we extend these studies via pharmacological inhibition of the Arp2/3 complex in sea urchin coelomocytes, cells that possess an unusually broad LP region and display correspondingly exaggerated centripetal flow. Using light and electron microscopy, we demonstrate that Arp2/3 complex inhibition via the drug CK666 dramatically altered LP actin architecture, slowed centripetal flow, drove a lamellipodial-to-filopodial shape change in suspended cells, and induced a novel actin structural organization during cell spreading. A general feature of the CK666 phenotype in coelomocytes was transverse actin arcs, and arc generation was arrested by a formin inhibitor. We also demonstrate that CK666 treatment produces actin arcs in other cells with broad LP regions, namely fish keratocytes and Drosophila S2 cells. We hypothesize that the actin arcs made visible by Arp2/3 complex inhibition in coelomocytes may represent an exaggerated manifestation of the elongate mother filaments that could possibly serve as the scaffold for the production of the dendritic actin network.This research was supported by National Science Foundation STEP grant 0856704 to Dickinson College, student/faculty summer research grants from the Dickinson College Research and Development Committee, Laura and Arthur Colwin Summer Research Fellowships from the Marine Biological Laboratory to J.H.H. and C.B.S., National Institutes of Health Grant EB002583 to R.O., and National Science Foundation collaborative research grants to J.H.H. (MCB-1412688) and C.B.S. (MCB-1412734)
Embodied Knowledge: Writing Researchersâ Bodies Into Qualitative Health Research
After more than a decade of postpositivist health care research and an increase in narrative writing practices, social scientific, qualitative health research remains largely disembodied. The erasure of researchersâ bodies from conventional accounts of research obscures the complexities of knowledge production and yields deceptively tidy accounts of research. Qualitative health research could benefit significantly from embodied writing that explores the discursive relationship between the body and the self and the semantic challenges of writing the body by incorporating bodily details and experiences into research accounts. Researchers can represent their bodies by incorporating autoethnographic narratives, drawing on all of their senses, interrogating the connections between their bodily signifiers and research processes, and experimenting with the semantics of self and body. The author illustrates opportunities for embodiment with excerpts from an ethnography of a geriatric oncology team and explores implications of embodied writing for the practice of qualitative health research
Access to justice for all: Towards an âexpansive visionâ of justice and technology.
In this paper, the authors examine developments in the Canadian access to justice dialogue from Macdonaldâs seminal 2005 analysis to the recent reports of the National Action Committee on Access to Justice in Civil and Family Matters [NAC]. They draw on the NACâs call for an âexpansive visionâ of access to justice as the basis for critically evaluating examples of particular technologies used or proposed as responses to the access to justice crisis in Canada. In so doing, they illustrate the importance of conscious consideration of deliverables and beneficiaries in prioritizing technologies for deployment, in determining how the technology ought to be deployed, and in evaluating the potential of a technology to facilitate access to justice. The authors argue that nuanced accounts of the relationships between justice deliverables, technological mechanisms for delivery and intended justice beneficiaries are essential to developing good decision-making mechanisms with respect to access to justice and technology.
Dans le prĂ©sent article, les auteurs examinent lâĂ©volution du dialogue canadien sur lâaccĂšs Ă la justice, depuis lâanalyse fondamentale de Macdonald en 2005 jusquâaux rĂ©cents rapports du ComitĂ© national dâaction sur lâaccĂšs Ă la justice en matiĂšre civile et familiale (CNA). Ils se fondent sur la « vision Ă©largie » de lâaccĂšs Ă la justice rĂ©clamĂ©e par le CNA pour Ă©valuer de façon critique les exemples de technologies particuliĂšres utilisĂ©es ou proposĂ©es pour rĂ©pondre Ă la crise de lâaccĂšs Ă la justice au Canada. Ce faisant, ils illustrent lâimportance dâexaminer de façon consciente les livrables et les bĂ©nĂ©ficiaires pour classer par ordre de prioritĂ© les technologies Ă dĂ©ployer, pour dĂ©terminer comment la technologie devrait ĂȘtre dĂ©ployĂ©e et pour Ă©valuer le potentiel dâune technologie de faciliter lâaccĂšs Ă la justice. Les auteurs soutiennent que des comptes rendus nuancĂ©s des rapports entre les livrables en matiĂšre de justice, les mĂ©canismes de livraison technologiques et les bĂ©nĂ©ficiaires prĂ©vus sont essentiels pour Ă©laborer de bons mĂ©canismes dĂ©cisionnels en ce qui concerne lâaccĂšs Ă la justice et la technologie
Scattering of short laser pulses from trapped fermions
We investigate the scattering of intense short laser pulses off trapped cold
fermionic atoms. We discuss the sensitivity of the scattered light to the
quantum statistics of the atoms. The temperature dependence of the scattered
light spectrum is calculated. Comparisons are made with a system of classical
atoms who obey Maxwell-Boltzmann statistics. We find the total scattering
increases as the fermions become cooler but eventually tails off at very low
temperatures (far below the Fermi temperature). At these low temperatures the
fermionic degeneracy plays an important role in the scattering as it inhibits
spontaneous emission into occupied energy levels below the Fermi surface. We
demonstrate temperature dependent qualitative changes in the differential and
total spectrum can be utilized to probe quantum degeneracy of trapped Fermi gas
when the total number of atoms are sufficiently large . At smaller
number of atoms, incoherent scattering dominates and it displays weak
temperature dependence.Comment: updated figures and revised content, submitted to Phys.Rev.
Sympathetic cooling of an atomic Bose-Fermi gas mixture
Sympathetic cooling of an atomic Fermi gas by a Bose gas is studied by
solution of the coupled quantum Boltzmann equations for the confined gas
mixture. Results for equilibrium temperatures and relaxation dynamics are
presented, and some simple models developed. Our study illustrate that a
combination of sympathetic and forced evaporative cooling enables the Fermi gas
to be cooled to the degenerate regime where quantum statistics, and mean field
effects are important. The influence of mean field effects on the equilibrium
spatial distributions is discussed qualitatively.Comment: 8 pages, 9 figures, accepted for publication in Phys.Rev.Let
The Short-Term Effect of Video Editing Pace on Childrenâs Inhibition and N2 and P3 ERP Components during Visual Go/No-Go Task
We investigated the immediate consequences of differently paced videos on behaviour and neural activity during response inhibition. Forty 7-year-olds watched a fast- or slow-paced video and completed a go/no-go task. Compared to the slow-paced-video group, children in the fast-paced-video group made more no-go errors. There was also an interaction between pace and no-go response type (correct, wrong) for the N2 and P3 peak latencies. In the slow-paced group, both components peaked earlier for correct response withholds. This usual pattern of activation was absent in the fast-paced group. Video pace appears to affect behaviour and the neural responses involved in inhibition
Production of pizero and eta mesons at large transverse momenta in pi-p and pi-Be interactions at 515 GeV/c
We present results on the production of high transverse momentum pizero and
eta mesons in pi-p and pi-Be interactions at 515 GeV/c. The data span the
kinematic ranges 1 < p_T < 11 GeV/c in transverse momentum and -0.75 < y < 0.75
in rapidity. The inclusive pizero cross sections are compared with
next-to-leading order QCD calculations and to expectations based on a
phenomenological parton-k_T model.Comment: RevTeX4, 15 pages, 15 figures, to be submitted to Phys. Rev.
Evaporative Cooling of a Two-Component Degenerate Fermi Gas
We derive a quantum theory of evaporative cooling for a degenerate Fermi gas
with two constituents and show that the optimum cooling trajectory is
influenced significantly by the quantum statistics of the particles. The
cooling efficiency is reduced at low temperatures due to Pauli blocking of
available final states in each binary collision event. We compare the
theoretical optimum trajectory with experimental data on cooling a quantum
degenerate cloud of potassium-40, and show that temperatures as low as 0.3
times the Fermi temperature can now be achieved.Comment: 6 pages, 4 figure
- âŠ