Arjunolic acid derivative glycoside from the stems of Hedera colchica

Five triterpenoid saponins were isolated from the stems of Hedera colchica K. Koch (Araliaceae). Two of them are new natural substances. HCS-A (1): 3-O-α-L-arabinopyranoside, 28-O-α-L-rhamnopyranosyl-(1→ 4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-arjunolic acid. HCSt-B (2):3-O-β-D-xylopyranoside, 28-O-α-L-rhamnopyranosyl- (1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl- hederagenin. A derivative of arjunolic acid is described for the first time in the Araliaceae family. The chemical structures of isolated compounds were established on the basis of chemical and 1D and 2D NMR experiments

Arjunolic acid derivative glycoside from the stems of Hedera colchica

Five triterpenoid saponins were isolated from the stems of Hedera colchica K. Koch, Araliaceae. Two of them are new natural substances. HCSt-A (1): 3-O-α-D-arabinopyranoside; 28-O-α-L-rhamnopyranosyl-(1→4)-O- β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-arjunolic acid. HCSt-B (2): 3-O-β-D-xylopyranoside; 28-O-α-L-rhamnopyranosyl- (1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl- hederagenin. The derivative of arjunolic acid is described for the first time in Araliaceae family. The chemical structures of isolated compounds were established on the base of chemical and 1D and 2D NMR experiments

Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S.Caucasicum Bieb. (Boraginaceae)

Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene], according to IR and NMR spectroscopy. The Symphytum high-molecular preparations can modulate in vitro B- chronic lymphocytic leukaemia (B-CLL) cells apoptosis and cell cycle progression