Baseline studies and evaluation of the physical, chemical, and biological characteristics of nearshore dredge spoil disposal, Pearl Harbor, Hawaii: Part A: Baseline studies, investigation and selection of a suitable dredge spoil site; final report

Results of the geology, physical oceanography, water chemistry and biological baseline investigations of the proposed dredge spoil disposal site off Pearl Harbor, Honolulu, Hawaii, have yielded no evidence to suggest that dumping of dredge spoil will create significant adverse effects on the environment. Results obtained during these investigations have shown that the proposed site is suitable as a permanent dredge spoil disposal site. Further confirmation of this conclusion will be obtained through the proposed monitoring activities conducted during actual disposal operations (phase B). The general circulation and current patterns in the disposal area lead to the further recommendation that actual dumping take place in the southeast corner of the disposal area, moving from east to west.Pacific Division Naval Facilities Engineering Command, Contract Number N62742-76, C-0050

A Longitudinal Study of Engineering Student Performance and Retention. V. Comparisons with Traditionally-Taught Students

In a longitudinal study at North Carolina State University, a cohort of students took five chemical engineering courses taught by the same instructor in five consecutive semesters. The courses made extensive use of active and cooperative learning and a variety of other techniques designed to address a broad spectrum of learning styles. Previous reports on the study summarized the instructional methods used in the experimental course sequence, described the performance of the cohort in the introductory chemical engineering course, and examined performance and attitude differences between students from rural and urban backgrounds and between male and female students.1–4 This paper compares outcomes for the experimental cohort with outcomes for students in a traditionally‐taught comparison group. The experimental group outperformed the comparison group on a number of measures, including retention and graduation in chemical engineering, and many more of the graduates in this group chose to pursue advanced study in the field. Since the experimental instructional model did not require small classes (the smallest of the experimental classes had 90 students) or specially equipped classrooms, it should be adaptable to any engineering curriculum at any institution

A geothermal plant from a time-scale perspective

In recent years, geothermal energy use from low-temperature sandstone reservoirs has sharply increased. Nonetheless, the injection of heat-depleted geothermal fluids has not been an easy task because of well/formation damage and operational/economic issues. Sønderborg geothermal plant is a case example of heat-mining from a low-temperature reservoir. It is in the northeast of Sønderborg towards Augustenborg Fjord. The present work takes into consideration the regional and local geology of the Sønderborg area, construction of the wells, field experience and water chemistry. The main issues of the geothermal plant appear to be related to the construction of the wells and reinjection of the heat-depleted brine. Our water chemistry analysis and PHREEQC simulations indicate that geothermal brine was saturated with respect to carbonate and barite minerals. The excess of Ca2+ and SO42− ions could have led to the formation and precipitation of carbonate and sulfate scales. Moreover, the increment of iron concentration over time could suggest the ingress of oxygen and pitting corrosion due to the presence of halide ions

The Effects of Personality Type on Engineering Student Performance and Attitudes

The Myers‐Briggs Type Indicator® (MBTI) was administered to a group of 116 students taking the introductory chemical engineering course at North Carolina State University. That course and four subsequent chemical engineering courses were taught in a manner that emphasized active and cooperative learning and inductive presentation of course material. Type differences in various academic performance measures and attitudes were noted as the students progressed through the curriculum. The observations were generally consistent with the predictions of type theory, and the experimental instructional approach appeared to improve the performance of MBTI types (extraverts, sensors, and feelers) found in previous studies to be disadvantaged in the engineering curriculum. The conclusion is that the MBTI is a useful tool for helping engineering instructors and advisors to understand their students and to design instruction that can benefit all of them

Steady-state response of a random dynamical system described with Padé approximants and random eigenmodes

Designing a random dynamical system requires the prediction of the statistics of the response, knowing the random model of the uncertain parameters. Direct Monte Carlo simulation (MCS) is the reference method for propagating uncertainties but its main drawback is the high numerical cost. A surrogate model based on a polynomial chaos expansion (PCE) can be built as an alternative to MCS. However, some previous studies have shown poor convergence properties around the deterministic eigenfrequencies. In this study, an extended Pade approximant approach is proposed not only to accelerate the convergence of the PCE but also to have a better representation of the exact frequency response, which is a rational function of the uncertain parameters. A second approach is based on the random mode expansion of the response, which is widely used for deterministic dynamical systems. A PCE approach is used to calculate the random modes. Both approaches are tested on an example to check their efficiency

Jaime Galvis y su particular forma de ganarse la vida.

Este proyecto se inició en la búsqueda de una historia de vida, después de esto se fomentó el deseo de seguir investigando con el fin de buscar respuestas a toda las situaciones que se presentaban en el barrio Primero de mayo y así conseguir una temática fuerte y consistente para la construcción de un proyecto de grado con miras a graduarnos. Por tal razón nuestra principal justificación es que cada historia merece ser contada y esta es una de ellas, sentimos la necesidad de ser los encargados de contar una problemática, de interactuar y de abrir los ojos a situaciones que son normales para algunas personas que viven el Barrio, pero que para nosotros es algo muy particular. Queremos mostrar varios contrastes partiendo a través de un personaje que vive en una ciudad que se hace llamar “La Puerta de Oro”. A través de “Pin” pretendemos reflejar la realidad y el extremo de muchas personas que a diario luchan incesantemente para mejorar sus condiciones de vida, poniendo en riesgo su integridad personal y haciendo actividades ilegales. En este proyecto audiovisual narraremos la historia de Jaime Galvis, popularmente conocido como “Pin” un hombre de 23 años de edad, que diariamente recorre algunos sectores de Barranquilla en un vehículo de tracción animal para recolectar llantas y quemarlas para extraerles el acero. Aunque “Pin” es consciente de los peligros a los que ésta actividad lo lleva; como la inhalación de sustancias tóxicas que ponen en riesgo su salud, los efectos nocivos que causa al medio ambiente y constantes desacuerdos con los vecinos por desempeñar esta actividad ilegal, él ve esa actividad como su única forma de sobrevivir. Debido a las constantes prohibiciones realizadas por entidades encargadas del medio ambiente, Pin ve poco a poco como decae el negocio de la quema de llantas y cómo se hace más difícil adaptarse a otras actividades

Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study

BACKGROUND Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasites, which sustain infections over long periods and the immature derived sexual stages responsible for infecting mosquitoes and onward transmission. Early studies reported a temporal association between ACT introduction and reduced malaria transmission in a number of ecological settings. However, these reports have come from areas with low to moderate malaria transmission, been confounded by the presence of other interventions or environmental changes that may have reduced malaria transmission, and have not included a comparison group without ACT. This report presents results from the first large-scale observational study to assess the impact of case management with ACT on population-level measures of malaria endemicity in an area with intense transmission where the benefits of effective infection clearance might be compromised by frequent and repeated re-infection. METHODS A pre-post observational study with a non-randomized comparison group was conducted at two sites in Tanzania. Both sites used sulphadoxine-pyrimethamine (SP) monotherapy as a first-line anti-malarial from mid-2001 through 2002. In 2003, the ACT, artesunate (AS) co-administered with SP (AS + SP), was introduced in all fixed health facilities in the intervention site, including both public and registered non-governmental facilities. Population-level prevalence of Plasmodium falciparum asexual parasitaemia and gametocytaemia were assessed using light microscopy from samples collected during representative household surveys in 2001, 2002, 2004, 2005 and 2006. FINDINGS Among 37,309 observations included in the analysis, annual asexual parasitaemia prevalence in persons of all ages ranged from 11% to 28% and gametocytaemia prevalence ranged from <1% to 2% between the two sites and across the five survey years. A multivariable logistic regression model was fitted to adjust for age, socioeconomic status, bed net use and rainfall. In the presence of consistently high coverage and efficacy of SP monotherapy and AS + SP in the comparison and intervention areas, the introduction of ACT in the intervention site was associated with a modest reduction in the adjusted asexual parasitaemia prevalence of 5 percentage-points or 23% (p < 0.0001) relative to the comparison site. Gametocytaemia prevalence did not differ significantly (p = 0.30). INTERPRETATION The introduction of ACT at fixed health facilities only modestly reduced asexual parasitaemia prevalence. ACT is effective for treatment of uncomplicated malaria and should have substantial public health impact on morbidity and mortality, but is unlikely to reduce malaria transmission substantially in much of sub-Saharan Africa where individuals are rapidly re-infected.Financial support for IMPACT-Tz came primarily from CDC, the U.S. Agency for International Development and the Wellcome Trust

Epidemiologic Differences Between Cyclosporiasis and Cryptosporidiosis in Peruvian Children

We compared the epidemiologic characteristics of cyclosporiasis and cryptosporidiosis in data from a cohort study of diarrhea in a periurban community near Lima, Peru. Children had an average of 0.20 episodes of cyclosporiasis/year and 0.22 episodes of cryptosporidiosis/year of follow-up. The incidence of cryptosporidiosis peaked at 0.42 for 1-year-old children and declined to 0.06 episodes/child-year for 5- to 9-year-old children. In contrast, the incidence of cyclosporiasis was fairly constant among 1- to 9-year-old children (0.21 to 0.28 episodes/child-year). Likelihood of diarrhea decreased significantly with each episode of cyclosporiasis; for cryptosporidiosis, this trend was not statistically significant. Both infections were more frequent during the warm season (December to May) than the cooler season (June to November). Cryptosporidiosis was more frequent in children from houses without a latrine or toilet. Cyclosporiasis was associated with ownership of domestic animals, especially birds, guinea pigs, and rabbits

Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines

BACKGROUND: Acute malaria has been associated with a decreased antibody response to tetanus and diphtheria toxoids, meningococcal, salmonella, and Hib vaccines. Interest in giving malaria drug therapy and prevention at the time of childhood immunizations has increased greatly following recent trials of intermittent preventive therapy during infancy (IPTi), stimulating this re-analysis of unpublished data. The effect of malaria chemoprophylaxis on vaccine response was studied following administration of measles vaccines and diphtheria-tetanus-whole cell pertussis (DTP) vaccines. METHODS: In 1975, six villages divided into two groups of children ≤74 months of age from Burkina Faso, were assigned to receive amodiaquine hydrochloride chemoprophylaxis (CH+) every two weeks for seven months or no chemoprophylaxis (CH-). After five months, children in each group received either one dose of measles or two doses of DTP vaccines. RESULTS: For recipients of the measles vaccine, the seroconversion rates in CH+ and CH- children, respectively, were 93% and 96% (P > 0.05). The seroresponse rates in CH+ and CH- children respectively, were 73% and 86% for diphtheria (P > 0.05) and 77% and 91% for tetanus toxoid (P > 0.05). In a subset analysis, in which only children who strictly adhered to chemoprophylaxis criteria were included, there were, likewise, no significant differences in seroconversion or seroresponse for measles, diphtheria, or tetanus vaccines (P > 0.05). While analysis for pertussis showed a 43% (CH+) and 67% (CH-) response (P < 0.05), analyses using logistic regression to control for sex, age, chemoprophylaxis, weight-for-height Z-score, and pre-vaccination geometric mean titer (GMT), demonstrated that chemoprophylaxis was not associated with a significantly different conversion rate following DTP and measles vaccines. Seven months of chemoprophylaxis decreased significantly the malaria IFA and ELISA GMTs in the CH+ group. CONCLUSION: Malaria chemoprophylaxis prior to vaccination in malaria endemic settings did not improve or impair immunogenicity of DTP and measles vaccines. This is the first human study to look at the association between malaria chemoprophylaxis and the serologic response to whole-cell pertussis vaccine