19,443 research outputs found

    Detecting variable responses in time-series using repeated measures ANOVA: Application to physiologic challenges.

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    We present an approach to analyzing physiologic timetrends recorded during a stimulus by comparing means at each time point using repeated measures analysis of variance (RMANOVA). The approach allows temporal patterns to be examined without an a priori model of expected timing or pattern of response. The approach was originally applied to signals recorded from functional magnetic resonance imaging (fMRI) volumes-of-interest (VOI) during a physiologic challenge, but we have used the same technique to analyze continuous recordings of other physiological signals such as heart rate, breathing rate, and pulse oximetry. For fMRI, the method serves as a complement to whole-brain voxel-based analyses, and is useful for detecting complex responses within pre-determined brain regions, or as a post-hoc analysis of regions of interest identified by whole-brain assessments. We illustrate an implementation of the technique in the statistical software packages R and SAS. VOI timetrends are extracted from conventionally preprocessed fMRI images. A timetrend of average signal intensity across the VOI during the scanning period is calculated for each subject. The values are scaled relative to baseline periods, and time points are binned. In SAS, the procedure PROC MIXED implements the RMANOVA in a single step. In R, we present one option for implementing RMANOVA with the mixed model function "lme". Model diagnostics, and predicted means and differences are best performed with additional libraries and commands in R; we present one example. The ensuing results allow determination of significant overall effects, and time-point specific within- and between-group responses relative to baseline. We illustrate the technique using fMRI data from two groups of subjects who underwent a respiratory challenge. RMANOVA allows insight into the timing of responses and response differences between groups, and so is suited to physiologic testing paradigms eliciting complex response patterns

    Berlioz, Love, and <i>Béatrice et Bénédict</i>

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    Berlioz's final opera, Béatrice et Bénédict (1860–62) has generally been considered a light-hearted work, revelling in the simple joys of love. Yet his final development of the theme of love, which had preoccupied him at least since the Symphonie fantastique (1830), makes this opéra comique more serious than it might appear to be. Drawing on theories of the human subject by Badiou, Žižek, and Lacan, as well as on the resources of Schenkerian theory, this article invites a new attention on the ideological violence done both by conventional models of love (in this case, on the main characters in the opera) and by the language of tonality. Evaluation of the musical means by which Berlioz psychoanalyzes the characters of a masochist, Héro, and a hysteric, Béatrice, ultimately reveals a surprisingly provocative work of vivid psychological drama.</jats:p

    Thermal conductive connection and method of making same Patent

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    Thermal conductive, electrically insulated cleavable adhesive connection between electronic module and heat sin

    Far infrared maps of the ridge between OMC-1 and OMC-2

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    Dust continuum emission from a 6 ft x 20 ft region surrounding OMC-1 and OMC-2 were mapped at 55 and 125 microns with 4 ft resolution. The dominant features of the maps are a strong peak at OMC-1 and a ridge of lower surface brightness between OMC-1 and OMC-2. Along the ridge the infrared flux densities and the color temperature decreases smoothly from OMC-1 to OMC-2. OMC-1 is heated primarily by several optical and infrared stars situated within or just at the boundary of the cloud. At the region of minimum column density between OMC-1 and OMC-2 the nearby B0.5 V star NU Ori may contribute significantly to the dust heating. Near OMC-2 dust column densities are large enough so that, in addition to the OMC-2 infrared cluster, the nonlocal infrared sources associated with OMC-1 and NU Ori can contribute to the heating

    Analytical and experimental study of stratification and liquid-ullage coupling, 1 June 1964 - 31 May 1965

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    Closed-form solution for stratification of subcooled fluids in containers subjected to heating, and for liquid-ullage vapor couplin

    The Occurrence of Rhopilema verrilli (Cnidaria: Scyphozoa: Rhizostomeae) on Galveston Island, Texas, and a Discussion on Its Distribution in U.S. Waters

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    A specimen of the rhizostome scyphomedusa Rhopilema verrilli was stranded on the beach at Galveston Island, Texas, in the spring of 1985. Two young specimens have since been collected In the marshes on the north side of Galveston bordering West Galveston Bay. This species Is relatively rare throughout most of Its range and has only been reported once before in the western Gulf of Mexico. Seasonal and geographic distributions from literature records are discussed in relation to temperature, salinity, currents, and life history. Occurrences along the U.S. East Coast Indicate progressively later seasonal appearances and decreased abundances from Georgia to New England. Occurrences In the Gulf of Mexico are almost all limited to the Mississippi Sound area. Collection records suggest that R. verrilli has two centers of distribution, one in southern U.S. East Coast waters and one in the northeastern Gulf of Mexico, and that occurrences outside these centers are due to transport by currents. We believe that R. verrilli\u27s apparent rarity in the western Gulf of Mexico results primarily from a combination of wind-driven current patterns, timing of volume of Mississippi-Aatchafalaya River discharge, and temperature-salinlty tolerances of the species acting against transport into, and survival in, the western Gulf

    ePortfolios: Mediating the minefield of inherent risks and tensions

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    The ePortfolio Project at the Queensland University of Technology (QUT) exemplifies an innovative and flexible harnessing of current portfolio thinking and design that has achieved substantial buy-in across the institution with over 23000 active portfolios. Robust infrastructure support, curriculum integration and training have facilitated widespread take-up, while QUT’s early adoption of ePortfolio technology has enabled the concomitant development of a strong policy and systems approach to deal explicitly with legal and design responsibilities. In the light of that experience, this paper will highlight the risks and tensions inherent in ePortfolio policy, design and implementation. In many ways, both the strengths and weaknesses of ePortfolios lie in their ability to be accessed by a wider, less secure audience – either internally (e.g. other students and staff) or externally (e.g. potential employees and referees). How do we balance the obvious requirement to safeguard students from the potential for institutionally-facilitated cyber-harm and privacy breaches, with this generation’s instinctive personal and professional desires for reflections, private details, information and intellectual property to be available freely and with minimal restriction? How can we promote collaboration and freeform expression in the blog and wiki world but also manage the institutional risk that unauthorised use of student information and work so palpably carries with it? For ePortfolios to flourish and to develop and for students to remain engaged in current reflective processes, holistic guidelines and sensible boundaries are required to help safeguard personal details and journaling without overly restricting students’ emotional, collaborative and creative engagement with the ePortfolio experience. This paper will discuss such issues and suggest possible ways forward

    Pairs of Bloch electrons and magnetic translation groups

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    A product of irreducible representations of magnetic translation group is considered. It leads to irreducible representations which were previously rejected as nonphysical. A very simple example indicates a possible application of these representations. In particular, they are important in descriptions of pairs of electrons in a magnetic field and a periodic potential. The periodicity of some properties with respect to the charge of a particle is briefly discussed.Comment: 4 pages, RevTex. Latex2.09, amsfont

    Nanostructure and crystallography of aberrant columnar vaterite in Corbicula fluminea (Mollusca)

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    Both the crystallographic and nanostructural organisation of aberrant columnar vaterite occurring in \ud C. fluminea were characterised in detail for the first time using electron microscopic and x-ray \ud powder diffraction techniques. At the millimetre scale, only a confinement of the otherwise \ud randomly oriented c-axis to the growth surface is observed. Domains of one hundred or more \ud individual vaterite columns with common c-axis orientation exist within this disordered material. \ud Each column behaves as a single crystal on the scale of EBSD measurements, but is internally \ud composed of smaller (0.3 – 1.3 μm in dimension) irregularly shaped and slightly misaligned \ud crystalline units. These are in turn partitioned by porous boundaries into rounded nanodomains, up \ud to 600 nm in size. The geometry of the nanodomains and their respective boundaries might suggest \ud formation by the accretion of vesicles. In addition to crystallographic textures, this observation \ud indicates formation under significant biological control with wider implications for possible causes \ud of the condition
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