2,126 research outputs found

    Evolving a Common Environmental Policy Framework in the South South Geopolitical Zone of Nigeria.

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    This paper is simply a proposition for an ideal environmental policy tenable for a geographical entity that has a common environmental problem, cultural affinity and a unique socio-cultural and political background. The article x-rays some existing legal and institutional arrangements for environmental policy implementation in the area. It also proposes an environmental policy pathway which could be adopted to suit the different entities that make up the South South geopolitical zone. The paper finally provides a framework for a common environmental policy awareness and control in the area. Key words: Environment, Policy, Framework, Institution, Cycle

    Stability of a neural network model with small-world connections

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    Small-world networks are highly clustered networks with small distances among the nodes. There are many biological neural networks that present this kind of connections. There are no special weightings in the connections of most existing small-world network models. However, this kind of simply-connected models cannot characterize biological neural networks, in which there are different weights in synaptic connections. In this paper, we present a neural network model with weighted small-world connections, and further investigate the stability of this model.Comment: 4 pages, 3 figure

    50 Years of Test (Un)fairness: Lessons for Machine Learning

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    Quantitative definitions of what is unfair and what is fair have been introduced in multiple disciplines for well over 50 years, including in education, hiring, and machine learning. We trace how the notion of fairness has been defined within the testing communities of education and hiring over the past half century, exploring the cultural and social context in which different fairness definitions have emerged. In some cases, earlier definitions of fairness are similar or identical to definitions of fairness in current machine learning research, and foreshadow current formal work. In other cases, insights into what fairness means and how to measure it have largely gone overlooked. We compare past and current notions of fairness along several dimensions, including the fairness criteria, the focus of the criteria (e.g., a test, a model, or its use), the relationship of fairness to individuals, groups, and subgroups, and the mathematical method for measuring fairness (e.g., classification, regression). This work points the way towards future research and measurement of (un)fairness that builds from our modern understanding of fairness while incorporating insights from the past.Comment: FAT* '19: Conference on Fairness, Accountability, and Transparency (FAT* '19), January 29--31, 2019, Atlanta, GA, US

    Projecting the Contribution of Provitamin A Maize Biofortification and Other Nutrition Interventions to the Nutritional Adequacy and Cost of Diets in Rural Zimbabwe

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    Background Evidence of the effectiveness of biofortified maize with higher provitamin A (PVA) to address vitamin A deficiency in rural Africa remains scant. Objectives This study projects the impact of adopting PVA maize for a diversity of households in an area typical of rural Zimbabwe and models the cost and composition of diets adequate in vitamin A. Methods Household-level weighed food records were generated from 30 rural households during a week in April and November 2021. Weekly household intakes were calculated, as well as indicative costs of diets using data from market surveys. The impact of PVA maize adoption was modeled assuming all maize products contained observed vitamin A concentrations. The composition and cost of the least expensive indicative diets adequate in vitamin A were calculated using linear programming. Results Very few households would reach adequate intake of vitamin A with the consumption of PVA maize. However, from a current situation of 33%, 50%–70% of households were projected to reach ≤50% of their requirements (the target of PVA), even with the modest vitamin A concentrations achieved on-farm (mean of 28.3 μg RAE per 100 g). This proportion would increase if higher concentrations recorded on-station were achieved. The estimated daily costs of current diets (mean ± standard deviation) were USD 1.43 ± 0.59 in the wet season and USD 0.96 ± 0.40 in the dry season. By comparison, optimization models suggest that diets adequate in vitamin A could be achieved at daily costs of USD 0.97 and USD 0.79 in the wet and dry seasons, respectively. Conclusions The adoption of PVA maize would bring a substantial improvement in vitamin A intake in rural Zimbabwe but should be combined with other interventions (e.g., diet diversification) to fully address vitamin A deficienc

    Spectral Properties and Synchronization in Coupled Map Lattices

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    Spectral properties of Coupled Map Lattices are described. Conditions for the stability of spatially homogeneous chaotic solutions are derived using linear stability analysis. Global stability analysis results are also presented. The analytical results are supplemented with numerical examples. The quadratic map is used for the site dynamics with different coupling schemes such as global coupling, nearest neighbor coupling, intermediate range coupling, random coupling, small world coupling and scale free coupling.Comment: 10 pages with 15 figures (Postscript), REVTEX format. To appear in PR

    In the Absence of Frazzled Over-Expression of Abelson Tyrosine Kinase Disrupts Commissure Formation and Causes Axons to Leave the Embryonic CNS

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    BACKGROUND: In the Drosophila embryonic nerve cord, the formation of commissures require both the chemoattractive Netrin receptor Frazzled (Fra) and the Abelson (Abl) cytoplasmic tyrosine kinase. Abl binds to the cytoplasmic domain of Fra and loss-of-function mutations in abl enhance fra-dependent commissural defects. To further test Abl's role in attractive signaling, we over-expressed Abl in Fra mutants anticipating rescue of commissures. METHODOLOGY/PRINCIPAL FINDINGS: The Gal4-UAS system was used to pan-neurally over-express Abl in homozygous fra embryos. Surprisingly, this led to a significant decrease in both posterior and anterior commissure formation and induced some commissural and longitudinal axons to project beyond the CNS/PNS border. Re-expressing wild-type Fra, or Fra mutants with a P-motif deleted, revert both commissural and exiting phenotypes, indicating that Fra is required but not a specific P-motif. This is supported by S2 cell experiments demonstrating that Abl binds to Fra independent of any specific P-motif and that Fra continues to be phosphorylated when individual P-motifs are removed. Decreasing midline repulsion by reducing Robo signaling had no effect on the Abl phenotype and the phenotypes still occur in a Netrin mutant. Pan-neural over-expression of activated Rac or Cdc42 in a fra mutant also induced a significant loss in commissures, but axons did not exit the CNS. CONCLUSION/SIGNIFICANCE: Taken together, these data suggest that Fra activity is required to correctly regulate Abl-dependent cytoskeletal dynamics underlying commissure formation. In the absence of Fra, increased Abl activity appears to be incorrectly utilized downstream of other guidance receptors resulting in a loss of commissures and the abnormal projections of some axons beyond the CNS/PNS border

    Passage of Time in a Planck Scale Rooted Local Inertial Structure

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    It is argued that the `problem of time' in quantum gravity necessitates a refinement of the local inertial structure of the world, demanding a replacement of the usual Minkowski line element by a 4+2n dimensional pseudo-Euclidean line element, with the extra 2n being the number of internal phase space dimensions of the observed system. In the refined structure, the inverse of the Planck time takes over the role of observer-independent conversion factor usually played by the speed of light, which now emerges as an invariant but derivative quantity. In the relativistic theory based on the refined structure, energies and momenta turn out to be invariantly bounded from above, and lengths and durations similarly bounded from below, by their respective Planck scale values. Along the external timelike world-lines, the theory naturally captures the `flow of time' as a genuinely structural attribute of the world. The theory also predicts expected deviations--suppressed quadratically by the Planck energy--from the dispersion relations for free fields in the vacuum. The deviations from the special relativistic Doppler shifts predicted by the theory are also suppressed quadratically by the Planck energy. Nonetheless, in order to estimate the precision required to distinguish the theory from special relativity, an experiment with a binary pulsar emitting TeV range gamma-rays is considered in the context of the predicted deviations from the second-order shifts.Comment: 17 pages; Diagram depicting "the objective flow of time" is replaced with a much-improved diagra

    TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

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    Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ. Systematic reviews show that all relevant studies are small and none are likely to have adequate power to show true differences between treatments. Worldwide, current treatment is not based on evidence from randomised trials. In Brazil, the combination haloperidol-promethazine is frequently used, but no studies involving this mix exist. TREC-Rio (Tranquilização Rápida-Ensaio Clínico [Translation: Rapid Tranquillisation-Clinical Trial]) will compare midazolam with haloperidol-promethazine mix for treatment of agitated patients in emergency psychiatric rooms of Rio de Janeiro, Brazil. TREC-Rio is a randomised, controlled, pragmatic and open study. Primary measure of outcome is tranquillisation at 20 minutes but effects on other measures of morbidity will also be assessed. TREC-Rio will involve the collaboration of as many health care professionals based in four psychiatric emergency rooms of Rio as possible. Because the design of this trial does not substantially complicate clinical management, and in several aspects simplifies it, the study can be large, and treatments used in everyday practice can be evaluated

    Measuring differential rotation of the K-giant ζ\zeta\,And

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    We investigate the temporal spot evolution of the K-giant component in the RS CVn-type binary system ζ\zeta\,Andromedae to establish its surface differential rotation. Doppler imaging is used to study three slightly overlapping spectroscopic datasets, obtained independently at three different observing sites. Each dataset covers one full stellar rotation with good phase coverage, and in total, results in a continuous coverage of almost three stellar rotations (Prot=P_{\rm rot}=17.8\,d). Therefore, these data are well suited for reconstructing surface temperature maps and studying temporal evolution in spot configurations. Surface differential rotation is measured by the means of cross-correlation of all the possible image pairs. The individual Doppler reconstructions well agree in the revealed spot pattern, recovering numerous low latitude spots with temperature contrasts of up to ≈\approx1000\,K with respect to the unspotted photosphere, and also an asymmetric polar cap which is diminishing with time. Our detailed cross-correlation study consistently indicate solar-type differential rotation with an average surface shear α≈0.055\alpha\approx0.055, in agreement with former results.Comment: accepted for publication in A&A, 4 pages, 3 figure
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