The Newman-Janis Algorithm, Rotating Solutions and Einstein-Born-Infeld Black Holes

A new metric is obtained by applying a complex coordinate trans- formation to the static metric of the self-gravitating Born-Infeld monopole. The behaviour of the new metric is typical of a rotating charged source, but this source is not a spherically symmetric Born-Infeld monopole with rotation. We show that the structure of the energy-momentum tensor obtained with this new metric does not correspond to the typical structure of the energy momentum tensor of Einstein-Born-Infeld theory induced by a rotating spherically symmetric source. This also show, that the complex coordinate transformations have the interpretation given by Newman and Janis only in space-time solutions with linear sources

Von Neumann's Quantization of General Relativity

Von Neumann's procedure is applied for quantization of General Relativity. We quantize the initial data of dynamical variables at the Planck epoch, where the Hubble parameter coincides with the Planck mass. These initial data are defined via the Fock simplex in the tangent Minkowskian space-time and the Dirac conformal interval. The Einstein cosmological principle is applied for the average of the spatial metric determinant logarithm over the spatial volume of the visible Universe. We derive the splitting of the general coordinate transformations into the diffeomorphisms (as the object of the second N\"other theorem) and the initial data transformations (as objects of the first N\"other theorem). Following von Neumann, we suppose that the vacuum state is a quantum ensemble. The vacuum state is degenerated with respect to quantum numbers of non-vacuum states with the distribution function that yields the Casimir effect in gravidynamics in analogy to the one in electrodynamics. The generation functional of the perturbation theory in gravidynamics is given as a solution of the quantum energy constraint. We discuss the region of applicability of gravidynamics and its possible predictions for explanation of the modern observational and experimental data.Comment: 14 pages, updated version with extended discussio

Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental models

Highlights A svCRiSP from Mojave rattlesnake triggered the release of key pro-inflammatory cytokines and chemokines in cell lines. Early release of pro-inflammatory mediators was observed locally and systemically in mice treated with Css-CRiSP. This study provides further evidence of the pro-inflammatory effects of crotalid CRiSP. Css-CRiSP may modulate the vascular dysfunction and persistent inflammation seen in envenomings by Mojave rattlesnakes. Abstract Snake venoms contain various molecules known for activating innate immunity and causing local effects associated with increased vascular permeability, such as vascular leakage and edema, common symptoms seen in snakebite envenomings. We have demonstrated that snake venom cysteine-rich secretory proteins (svCRiSPs) from North American pit vipers increase vascular permeability. This study aimed to explore the functional role of CRiSP isolated from Mojave rattlesnake (Crotalus scutulatus scutulatus) venom (Css-CRiSP) on the activation of inflammatory responses in different models. We measured the release of inflammatory mediators in cultured human dermal blood endothelial cells (HDBEC), lymphatic endothelial cells (HDLEC) and monocyte-derived macrophages (MDM) at 0.5, 1, 3, 6, and 24 h after treatment with Css-CRiSP (1 μM). We also determined the acute inflammatory response in BALB/c mice 30 min after intraperitoneal injection of the toxin (2 μg/mouse). Css-CRiSP induced the production of IL-8 and IL-6, but not TNF-α, in HDBEC and HDLEC in a time-dependent manner. In addition, Css-CRiSP significantly enhanced the production of IL-6, TNF-α, IL-8, and IL-1β in MDM. Moreover, it caused a remarkable increase of chemotactic mediators in the exudates of experimental mice. Our results reveal that Css-CRiSPs can promote a sustained release of inflammatory mediators on cell lines and an acute activation of innate immunity in a murine model. These findings contribute to the growing body of evidence supporting the involvement of svCRiSPs in the augmentation of envenomation effects, specifically, the role of svCRiSPs in inducing vascular dysfunction, initiating early inflammatory responses, and facilitating the activation of leukocytes and releasing mediators. These findings will lead to a better understanding of the pathophysiology of envenoming by Mojave rattlesnakes, allowing the development of more efficient therapeutic strategies

Kernel weight in maize: genetic control of its physiological and compositional determinants in a dent × flint-caribbean RIL population

The genetic control of maize kernel weight (KW) determination could be studied through its physiological and/ or compositional determinants. Our objective was to dissect the genetic control of maize KW by analyzing its physiological (KGR: kernel growth rate; KFD: kernel filling duration) and compositional (protein, oil, starch) determinants in a dent×flint Caribbean RIL population, which combines a broad genetic background with grains of high added value for industry. An additional objective was to determine the stability of the genetic control under contrasting growing conditions, for which soil nitrogen offer was modified across experiments. Heritability (H2) values were high for KW (H2 = 0.74) and intermediate for the other traits (from 0.62 to 0.42). Kernel weight had a strong correlation with KFD (r = 0.69), KGR (r = 0.60) and protein concentration (r = 0.56). Ten joint QTL with inconsistent effects across years and seven epistatic interactions were detected. Despite changes in effect size, most QTL were significant under both environments. Nine QTL were associated with variations in potential KW (KW ), mean KW, KGR and oil concentration, eight with variations in protein and starch concentration and seven with KFD. Epistatic interactions were related to regions with significant main effects. The most important finding was the existence of a common QTL for KW , KGR and KFD on chromosome 5, for which there was no previous report. Results increased our knowledge on the genetic control of KW through its phenotypic and genetic correlation with KFD, confirming the need to explore different physiological strategies in different genetic backgrounds

Rotation and twist regular modes for trapped ghosts

A parameter-independent notion of stationary slow motion is formulated then applied to the case of stationary rotation of massless trapped ghosts. The excitations correspond to a rotation mode with angular momentum $J\neq 0$ and twist modes. It is found that the rotation mode, which has no parity, causes excess in the angular velocity of dragged distant coordinate frames in one sheet of the wormhole while in the other sheet the angular velocity of the ghosts is that of rotating stars: $2J/r^3$. As to the twist modes, which all have parity, they cause excess in the angular velocity of one of the throat's poles with respect to the other.Comment: 11 pages, 3 figures; General Relativity and Gravitation - 201

Emanation Study of Gas Radon on the Ancient Cuexcomate Geyser in Puebla City, Mexico

Radon measurements were collected over a period of nine months in the area of the ancient Cuexcomate geyser, in Puebla City. For measuring radon, the passive method of nuclear tracks in solids was used, using polycarbonate CR-39 as radiation sensitive material. Radon concentrations varied in strong anti-correlation with the rainfall intensity. And are lower compared to other locations, in concordance with the stratigraphic composition, as travertine and deposits of volcanic origin, corresponding to the geyser chemical composition and the active environment in the north part of the Trans-Mexican Volcanic Belt with an andesitic and basalt composition

Isolation of beneficial bacteria for heterocyclic hydrocarbon compounds removal from mariculture environment

Despite the obvious merits of mariculture or cultivation of marine organisms for food, this activity is highly susceptible to environmental chemical pollutants. Components such as polycyclic aromatic hydrocarbons (PAHs) and heterocyclic hydrocarbons (HH) compounds are known to accumulate in marine organisms through bioconcentration, which leads to food safety risks for humans. The objective of this is study is to isolate bacteria which can be utilized for heterocyclic hydrocarbon compounds removal from aquaculture environment. Seawater samples were collected from fisherman village Kampung Buntal, Sarawak and confirmation of the presence HH-degrading bacteria are conducted via enrichment cultures using artificial seawater ONR7a media supplemented with carbazole (CAR) as the sole carbon source. Bacterial isolation was conducted on double layered artificial seawater ONR7a agar, supplemented with HH compounds such as CAR, dibenzothiophene (DBT) and dibenzofuran (DBF). A total of four isolates have showed growth on CAR, DBT and DBF. Two most promising bacteria have been identified as Capnocytophaga sp. strain EC1 and Idiomarina sp. EC2. Gas chromatography–mass spectrometry (GC-MS) analyses were conducted to measure the degradation ability of these bacteria. After a period of 12 days, strain EC1 and EC2 were able to degrade 24.33% and 25.16% of CAR respectivel

Isolation of beneficial bacteria for heterocyclic hydrocarbon compounds removal from mariculture environment

Despite the obvious merits of mariculture or cultivation of marine organisms for food, this activity is highly susceptible to environmental chemical pollutants. Components such as polycyclic aromatic hydrocarbons (PAHs) and heterocyclic hydrocarbons (HH) compounds are known to accumulate in marine organisms through bioconcentration, which leads to food safety risks for humans. The objective of this is study is to isolate bacteria which can be utilized for heterocyclic hydrocarbon compounds removal from aquaculture environment. Seawater samples were collected from fisherman village Kampung Buntal, Sarawak and confirmation of the presence HH-degrading bacteria are conducted via enrichment cultures using artificial seawater ONR7a media supplemented with carbazole (CAR) as the sole carbon source. Bacterial isolation was conducted on double layered artificial seawater ONR7a agar, supplemented with HH compounds such as CAR, dibenzothiophene (DBT) and dibenzofuran (DBF). A total of four isolates have showed growth on CAR, DBT and DBF. Two most promising bacteria have been identified as Capnocytophaga sp. strain EC1 and Idiomarina sp. EC2. Gas chromatography–mass spectrometry (GC-MS) analyses were conducted to measure the degradation ability of these bacteria. After a period of 12 days, strain EC1 and EC2 were able to degrade 24.33% and 25.16% of CAR respectivel