119 research outputs found

    Lexical interaction of the modern Greek language with Germanic and Romance languages (with reference to the vocabulary of English, French and modern Greek languages)

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    The article deals with the issues of lexical interaction of the modern Greek language with Germanic and Romance languages (represented by English and French). There were singled out two areas in which this lexical interaction is rather significant: the vocabulary related to food and drinks and the vocabulary used to designate objects and concepts of clothing, shoes, haberdashery and perfumer

    Application of information and analytical system of analysis of the financial condition and business activity of the enterprise

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    The work is devoted to the questions of the information-analytical system of analysis of the financial condition and business activity of the enterprise.Π Π°Π±ΠΎΡ‚Π° посвящСна вопросам ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎ-аналитичСской систСмы Π°Π½Π°Π»ΠΈΠ·Π° финансового состояния ΠΈ Π΄Π΅Π»ΠΎΠ²ΠΎΠΉ активности прСдприятия

    THE ROLE OF GROWTH AND ENDOTHELIAL FACTORS IN HEMOSTATIC DISORDER IN CHILDREN WITH THE SYNDROM DELAYED FETAL

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    Violation of the natural defense mechanisms of endothelial dysfunction and an imbalance can occur many neurohumoral factors. The imbalance of angiogenic and antiangiogenic growth factors, endothelial, platelet factor closely related to disorders of hemostasis, promotes the development of generalized endothelial dysfunction and is the basis of placental insufficiency, and is central to fetal growth and neonatal characteristics of the child’s development. The mechanisms regulating these processes in normal and pathological conditions play an important role of thromboxane and prostacyclin, which are derivatives of polyunsaturated fatty acids. Which indicates the feasibility of studying the role of vascular endothelial growth factor and hemostasis disorders in children with fetal growth retardation syndrome

    ΠŸΡ€ΠΈΠ½Ρ†ΠΈΠΏΡ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ модСлирования ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° развития Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° картофСля ΠΎΡ‚ агромСтСорологичСских условий

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    The purpose of the research: to develop verbal, analogous, mathematical models of projected growth of potato globoderosis depending on agrometeorological conditions. Materials and methods. Analysis of national and foreign literature regarding epiphytotiology, modeling was performed, as well as available literature data and personal supervision about influence of meteorological conditions on the potato globoderosis development were generalized. A database received in Kondrovo of Kaluga Region was used in order to develop verbal, analogous, mathematical model. One experimental field was chosen out of 40 experimental fields and plots of land where Sineglazka vulnerable variety was grown during 1979-1993. On the field with average soil quality the population density of nematodes varied from 14,900 to 27,300 (average 20,600) ovicells and larvas at the 100 cubic cm of soil. Globoderosis development was evaluated according to the scale for at-ground visual appraisal of defeat potato plants by globoderosis in points annually in July. Phenological, phytosanitary and phytohelminthological metering and supervision at the experimental field were conducted during vegetational season. Correlation and regression analysis of collected material was conducted using software application Microsoft Excel. Results and discussion. Π‘orrelation coefficient for meteorological factors closely related to globoderosis development over 15 years were calculated with the help of correlation analysis. Predictors (average daily temperature, quantity and amount of rainfall) for short period forecast of globoderosis development while planting of potatoes with average level of fertility were determined. As the result of regression analysis mathematic models of projected growth globoderosis depending on agrometeorological factors were received. Confidence of a mathematical model, i.e. differences of expectancy record from retrospective average 3.6%. Correspondence of mathematic model was checked by historical data using correlation coefficient between the result of projected growth globoderosis and measurement data. It is 0.83. Accuracy of forecast varied from -36.8 to 36.5%.ЦСль исслСдований: Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Ρ‚ΡŒ Π²Π΅Ρ€Π±Π°Π»ΡŒΠ½ΡƒΡŽ, Π°Π½Π°Π»ΠΎΠ³ΠΎΠ²ΡƒΡŽ, ΠΌΠ°Ρ‚Π΅ΠΌΠ°Ρ‚ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° развития Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° картофСля Π² зависимости ΠΎΡ‚ агромСтСорологичСских условий. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· отСчСствСнной ΠΈ Π·Π°Ρ€ΡƒΠ±Π΅ΠΆΠ½ΠΎΠΉ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹ ΠΏΠΎ вопросам эпифитотиологии, модСлирования, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΠ±ΠΎΠ±Ρ‰Π΅Π½Ρ‹ ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠ΅ΡΡ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π½Ρ‹Π΅ Π΄Π°Π½Π½Ρ‹Π΅ ΠΈ собствСнныС наблюдСния ΠΏΠΎ влиянию мСтСорологичСских условий Π½Π° Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° картофСля. Для Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ Π²Π΅Ρ€Π±Π°Π»ΡŒΠ½ΠΎΠΉ, Π°Π½Π°Π»ΠΎΠ³ΠΎΠ²ΠΎΠΉ, матСматичСской ΠΌΠΎΠ΄Π΅Π»ΠΈ Π±Ρ‹Π»Π° использована Π±Π°Π·Π° Π΄Π°Π½Π½Ρ‹Ρ…, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… Π² Π³. ΠšΠΎΠ½Π΄Ρ€ΠΎΠ²ΠΎ ΠšΠ°Π»ΡƒΠΆΡΠΊΠΎΠΉ области. Из 40 ΠΎΠΏΡ‹Ρ‚Π½Ρ‹Ρ… участков ΠΈ дСлянок Π±Ρ‹Π» Π²Ρ‹Π±Ρ€Π°Π½ ΠΎΠ΄ΠΈΠ½, Π½Π° ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΌ Π² Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ 1979-1993 Π³Π³. Π²Ρ‹Ρ€Π°Ρ‰ΠΈΠ²Π°Π»ΠΈ восприимчивый сорт Π‘ΠΈΠ½Π΅Π³Π»Π°Π·ΠΊΠ°. На участкС со срСдним ΠΏΠ»ΠΎΠ΄ΠΎΡ€ΠΎΠ΄ΠΈΠ΅ΠΌ ΠΏΠΎΡ‡Π²Ρ‹ ΠΏΠ»ΠΎΡ‚Π½ΠΎΡΡ‚ΡŒ популяции Π½Π΅ΠΌΠ°Ρ‚ΠΎΠ΄Ρ‹ колСбалась ΠΎΡ‚ 14 900 Π΄ΠΎ 27 300 (Π² срСднСм 20 600) яиц ΠΈ Π»ΠΈΡ‡ΠΈΠ½ΠΎΠΊ Π½Π° 100 ΠΊΡƒΠ±. см ΠΏΠΎΡ‡Π²Ρ‹. Π Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° ΠΎΡ†Π΅Π½ΠΈΠ²Π°Π»ΠΈ Π΅ΠΆΠ΅Π³ΠΎΠ΄Π½ΠΎ Π² июлС ΠΏΠΎ шкалС для Π½Π°Π·Π΅ΠΌΠ½ΠΎΠΉ Π²ΠΈΠ·ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ ΠΎΡ†Π΅Π½ΠΊΠΈ пораТСния Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·ΠΎΠΌ растСний картофСля Π² Π±Π°Π»Π»Π°Ρ…. Π’ Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π²Π΅Π³Π΅Ρ‚Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π° ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ фСнологичСскиС, фитосанитарныС ΠΈ Ρ„ΠΈΡ‚ΠΎΠ³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ ΡƒΡ‡Π΅Ρ‚Ρ‹ ΠΈ наблюдСния Π½Π° ΠΎΠΏΡ‹Ρ‚Π½ΠΎΠΌ участкС. ΠšΠΎΡ€Ρ€Π΅Π»ΡΡ†ΠΈΠΎΠ½Π½Ρ‹ΠΉ ΠΈ рСгрСссивный Π°Π½Π°Π»ΠΈΠ· собранного ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Π° Π±Ρ‹Π» ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ с использованиСм ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ Microsoft Excel. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ обсуТдСниС. Π‘ ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ коррСляционного Π°Π½Π°Π»ΠΈΠ·Π° Π±Ρ‹Π»ΠΈ рассчитаны коэффициСнты коррСляции для мСтСорологичСских Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ², тСсно связанных с Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ΠΌ Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° Π·Π° 15 Π»Π΅Ρ‚. ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΏΡ€Π΅Π΄ΠΈΠΊΡ‚ΠΎΡ€Ρ‹ (срСднСсуточная Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π°, количСство ΠΈ число осадков) для краткосрочных ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·ΠΎΠ² развития Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° Π½Π° посадках картофСля со срСдним ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ плодородия. Π’ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π΅ рСгрСссивного Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Ρ‹ матСматичСскиС ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° развития Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° Π² зависимости ΠΎΡ‚ агромСтСорологичСских Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ². Π”ΠΎΡΡ‚ΠΎΠ²Π΅Ρ€Π½ΠΎΡΡ‚ΡŒ матСматичСской ΠΌΠΎΠ΄Π΅Π»ΠΈ, Ρ‚.Π΅. ΠΎΡ‚Π»ΠΈΡ‡ΠΈΠ΅ расчСтных Π΄Π°Π½Π½Ρ‹Ρ… ΠΎΡ‚ рСтроспСктивных Π² срСднСм составляСт 3,6%. ΠΠ΄Π΅ΠΊΠ²Π°Ρ‚Π½ΠΎΡΡ‚ΡŒ матСматичСской ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΡ€ΠΎΠ²Π΅Ρ€Π΅Π½Π° Π½Π° рСтроспСктивных Π΄Π°Π½Π½Ρ‹Ρ… с использованиСм коэффициСнта коррСляции ΠΌΠ΅ΠΆΠ΄Ρƒ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠΌ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° развития Π³Π»ΠΎΠ±ΠΎΠ΄Π΅Ρ€ΠΎΠ·Π° ΠΈ фактичСскими Π΄Π°Π½Π½Ρ‹ΠΌΠΈ. Он Ρ€Π°Π²Π΅Π½ 0,83. ΠžΠΏΡ€Π°Π²Π΄Ρ‹Π²Π°Π΅ΠΌΠΎΡΡ‚ΡŒ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° Π²Π°Ρ€ΡŒΠΈΡ€ΡƒΠ΅Ρ‚ ΠΎΡ‚ -36,8 Π΄ΠΎ 35,6%

    Cognitive conceptualization and categorization of time definition in english, french and russian linguistics

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    The article is devoted to the description of linguocognitive categorization and conceptualization of time by the material of English, French and Russian languages. The process of categorization is aimed at combining similar or identical units into larger categories, and the process of conceptualization is aimed at highlighting the minimum meaningful units of human experience. The multilevel structure of the concept of TIME, due to the complementary nature of the analyzed category, is also considere

    Characteristics of the Plasma Disturbance Excited at Altitudes of 450–500 km During the β€œSura” Facility Operation

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    Β© 2018, Springer Science+Business Media, LLC, part of Springer Nature. We discuss the results of measuring characteristics of the artificial plasma disturbances excited at altitudes of 450–500 km with the ionospheric F2 layer modified by high-power HF radio waves from the Sura facility. It is found that at these altitudes there are plasma temperature and density variations in the HF-perturbed magnetic flux tube. No ducts with increased plasma density that were previously observed at altitudes of about 660 km were detected. The results of the studies are compared with the data from the DEMETER satellite and the results of radiotomographic measurements. It is noted that the field-aligned currents induced in a perturbed ionosphere during the Sura operation were detected for the first time using SWARM satellites

    Study of the structure formation during compression for selecting multiaxial deformation conditions for an Mg-Ca Alloy

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    The structure homogeneity of the Mg-0.8% Ca alloy is shown to increase with temperature during uniaxial compression. Plastic deformation localizes in narrow and wide deformation bands at 250-350Β°C. A small number of regions with recrystallized grains is observed only after deformation at 400Β°C. A relatively homogeneous recrystallized structure with an average grain size of about 20 ΞΌm forms after uniaxial compression at t = 450Β°

    ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π₯ассСла для прогнозирования плотности популяции золотистой ΠΊΠ°Ρ€Ρ‚ΠΎΡ„Π΅Π»ΡŒΠ½ΠΎΠΉ Π½Π΅ΠΌΠ°Ρ‚ΠΎΠ΄Ρ‹ послС выращивания глободСроустойчивого сорта картофСля

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    The purpose of the research is evaluation the possibility of application the Hassell model for prediction the dynamics of population density of golden nematode of potato in the ground after growing Globodera resistant variety of potato in the single-crop.Materials and methods. For the research database of population density of golden nematode of potato (amount of ootids and larvae) was used on the three plots where amenable varieties of potato were grown and one plot where Globodera resistant variety of potato Kardinal was grown in the Kaluga Region within 14 years (1979–1993). Non-linear least-squares method which is the version of least-squares method for non-linear systems was used as the method for evaluation the model parameters. Toolset of search for solution in the program Excel was used for analysis.Results and discussion. Hassell model for prediction the dynamics of population density of golden nematode of potato in the ground after growing Globodera resistant variety of potato in the single-crop demonstrated high confidence. (R2 = 0.94). Based on the Hassell model for development golden nematode of potato population in plot soil with growing nematode resistant variety modeling of introduction of Globodera resistant variety was conducted for different initial amount of golden nematode of potato and different levels of fertility of soil: low, average, high. Hassell model has confirmed that it is the most multifunctional in the category of discrete one-period models for prediction dynamics of population density of golden nematode of potato in the ground and permits to predict the amount of golden nematode of potato for agrobiocenosis with single-crop of potato of amenable and Globodera resistant varieties.ЦСль исслСдований: ΠΎΡ†Π΅Π½ΠΊΠ° возмоТности примСнСния ΠΌΠΎΠ΄Π΅Π»ΠΈ Π₯ассСла для прогнозирования Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ плотности популяции золотистой ΠΊΠ°Ρ€Ρ‚ΠΎΡ„Π΅Π»ΡŒΠ½ΠΎΠΉ Π½Π΅ΠΌΠ°Ρ‚ΠΎΠ΄Ρ‹ (Π—ΠšΠ) Π² ΠΏΠΎΡ‡Π²Π΅ послС выращивания глободСроустойчивых сортов картофСля Π² ΠΌΠΎΠ½ΠΎΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π΅.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Для исслСдования использован массив Π΄Π°Π½Π½Ρ‹Ρ… плотности популяций (число яиц ΠΈ Π»ΠΈΡ‡ΠΈΠ½ΠΎΠΊ) Π—ΠšΠ Π½Π° Ρ‚Ρ€Π΅Ρ… участках, Π³Π΄Π΅ Π²Ρ‹Ρ€Π°Ρ‰ΠΈΠ²Π°Π»ΠΈ восприимчивыС сорта картофСля, ΠΈ ΠΎΠ΄Π½ΠΎΠ³ΠΎ участка, Π³Π΄Π΅ Π²Ρ‹Ρ€Π°Ρ‰ΠΈΠ²Π°Π»ΠΈ глободСроустойчивый сорт картофСля ΠšΠ°Ρ€Π΄ΠΈΠ½Π°Π», Π² ΠšΠ°Π»ΡƒΠΆΡΠΊΠΎΠΉ области Π·Π° 14-Π»Π΅Ρ‚Π½ΠΈΠΉ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ (1979–1993 Π³Π³.). Π’ качСствС ΠΌΠ΅Ρ‚ΠΎΠ΄Π° ΠΎΡ†Π΅Π½ΠΊΠΈ ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€ΠΎΠ² ΠΌΠΎΠ΄Π΅Π»ΠΈ использовали Π½Π΅Π»ΠΈΠ½Π΅ΠΉΠ½Ρ‹ΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄ Π½Π°ΠΈΠΌΠ΅Π½ΡŒΡˆΠΈΡ… ΠΊΠ²Π°Π΄Ρ€Π°Ρ‚ΠΎΠ², ΡΠ²Π»ΡΡŽΡ‰ΠΈΠΉΡΡ ΠΌΠΎΠ΄ΠΈΡ„ΠΈΠΊΠ°Ρ†ΠΈΠ΅ΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° Π½Π°ΠΈΠΌΠ΅Π½ΡŒΡˆΠΈΡ… ΠΊΠ²Π°Π΄Ρ€Π°Ρ‚ΠΎΠ² для Π½Π΅Π»ΠΈΠ½Π΅ΠΉΠ½Ρ‹Ρ… систСм. Для Π°Π½Π°Π»ΠΈΠ·Π° Π±Ρ‹Π» ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ ΠΏΠ°ΠΊΠ΅Ρ‚ поиска Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ Π² ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ΅ Excel.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ обсуТдСниС. МодСль Π₯ассСла для прогнозирования Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ плотности популяции Π—ΠšΠ Π² ΠΏΠΎΡ‡Π²Π΅ послС выращивания Π² ΠΌΠΎΠ½ΠΎΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π΅ глободСрорустойчивого сорта картофСля ΠΏΠΎΠΊΠ°Π·Π°Π»Π° Π²Ρ‹ΡΠΎΠΊΡƒΡŽ Π΄ΠΎΡΡ‚ΠΎΠ²Π΅Ρ€Π½ΠΎΡΡ‚ΡŒ. (R2 = 0,94). На основании ΠΌΠΎΠ΄Π΅Π»ΠΈ Π₯ассСла для развития популяции Π—ΠšΠ Π² ΠΏΠΎΡ‡Π²Π΅ участка с Π²Ρ‹Ρ€Π°Ρ‰ΠΈΠ²Π°Π½ΠΈΠ΅ΠΌ нСматодоустойчивого сорта ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ ввСдСния глободСроустойчивого сорта для Ρ€Π°Π·Π»ΠΈΡ‡Π½ΠΎΠΉ Π½Π°Ρ‡Π°Π»ΡŒΠ½ΠΎΠΉ числСнности Π—ΠšΠ ΠΈ Ρ€Π°Π·Π½ΠΎΠ³ΠΎ уровня плодородия: Π½ΠΈΠ·ΠΊΠΎΠ³ΠΎ, срСднСго ΠΈ высокого. МодСль Π₯ассСла ΠΏΠΎΠ΄Ρ‚Π²Π΅Ρ€Π΄ΠΈΠ»Π°, Ρ‡Ρ‚ΠΎ являСтся Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡƒΠ½ΠΈΠ²Π΅Ρ€ΡΠ°Π»ΡŒΠ½ΠΎΠΉ Π² классС дискрСтных ΠΎΠ΄Π½ΠΎΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π½Ρ‹Ρ… ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ прогнозирования Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ плотности популяции Π—ΠšΠ Π² ΠΏΠΎΡ‡Π²Π΅ ΠΈ позволяСт ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Ρ‡ΠΈΡΠ»Π΅Π½Π½ΠΎΡΡ‚ΡŒ Π—ΠšΠ для Π°Π³Ρ€ΠΎΠ±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·ΠΎΠ² с ΠΌΠΎΠ½ΠΎΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€ΠΎΠΉ картофСля восприимчивых ΠΈ глободСроустойчивых сортов

    A clinical case of congenital hyperinsulinism in an early child

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    A clinical case of congenital hyperinsulinism, diffuse form, pharmacoresistant course (heterozygous mutation of p. 1361 1363 dup CGG in the GCK gene) in an early child is presented as an example of an orphan severe disease with an extremely unfavorable course and a probability of deterioration of the long-term prognosis. The goal was to highlight the clinical manifestations, course options, and complexity of treatment of this pathology to a wide range of doctors of different specialties in the field of Pediatrics in terms of improving the quality and timeliness of diagnosis, reducing the number of complications with the formation of irreparable consequences. Attention is drawn to the most severe course of hypoglycemic conditions in the early neonatal period, the dependence of the formation of a pronounced neurological deficit on the degree and duration of hypoglycemia, which emphasizes the importance of their timely correction to preserve the quality of life of this contingent of children
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