Reply to Comment by Galapon on 'Almost-periodic time observables for bound quantum systems'

In a recent paper [1] (also at http://lanl.arxiv.org/abs/0803.3721), I made several critical remarks on a 'Hermitian time operator' proposed by Galapon [2] (also at http://lanl.arxiv.org/abs/quant-ph/0111061). Galapon has correctly pointed out that remarks pertaining to 'denseness' of the commutator domain are wrong [3]. However, the other remarks still apply, and it is further noted that a given quantum system can be a member of this domain only at a set of times of total measure zero.Comment: 3 page

On the statistical evaluation of dose-response functions

The linear-quadratic dependence of effect on the dose of ionizing radiation and its biophysical implications are considered. The estimation of the parameters of the response function and the derivation of the joint confidence region of the estimates are described. The method is applied to the induction of pink mutations inTradescantia which follows the linear-quadratic model. The statistical procedure is also suitable for other response functions

Semirelativistic stability of N-boson systems bound by 1/r pair potentials

We analyze a system of self-gravitating identical bosons by means of a semirelativistic Hamiltonian comprising the relativistic kinetic energies of the involved particles and added (instantaneous) Newtonian gravitational pair potentials. With the help of an improved lower bound to the bottom of the spectrum of this Hamiltonian, we are able to enlarge the known region for relativistic stability for such boson systems against gravitational collapse and to sharpen the predictions for their maximum stable mass.Comment: 11 pages, considerably enlarged introduction and motivation, remainder of the paper unchange

Anomalous Hall effect in a two-dimensional electron gas

The anomalous Hall effect in a magnetic two-dimensional electron gas with Rashba spin-orbit coupling is studied within the Kubo-Streda formalism in the presence of pointlike potential impurities. We find that all contributions to the anomalous Hall conductivity vanish to leading order in disorder strength when both chiral subbands are occupied. In the situation that only the majority subband is occupied, all terms are finite in the weak scattering limit and the total anomalous Hall conductivity is dominated by skew scattering. We compare our results to previous treatments and resolve some of the discrepancies present in the literature.Comment: 11 pages, 5 figure

Data mining in bioinformatics using Weka

The Weka machine learning workbench provides a general purpose environment for automatic classification, regression, clustering and feature selection-common data mining problems in bioinformatics research. It contains an extensive collection of machine learning algorithms and data exploration and the experimental comparison of different machine learning techniques on the same problem. Weka can process data given in the form of a single relational table. Its main objectives are to (a) assist users in extracting useful information from data and (b) enable them to easily identify a suitable algorithm for generating an accurate predictive model from it

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.

This study was undertaken to determine the roles of individual alpha/beta 1 integrin heterodimers in promoting cellular interactions with the different attachment-promoting domains of laminin (LN). To do this, antibodies to the integrin beta 1 subunit or to specific integrin alpha subunits were tested for effects on cell attachment to LN, to elastase fragments E1-4 and E1, derived from the short arms and core of LN's cruciform structure, and to fragment E8 derived from the long arm of this structure. The human JAR choriocarcinoma cells used in this study attached to LN and to fragments E1 and E8. Attachment to E1-4 required a much higher substrate coating concentration, suggesting that it is a poor substrate for JAR cell attachment. The ability of cells to attach to different LN domains suggested the presence of more than one LN receptor. These multiple LN receptors were shown to be beta 1 integrin heterodimers because antibodies to the integrin beta 1 subunit inhibited attachment of JAR cells to LN and its three fragments. To identify the individual integrin alpha/beta 1 heterodimers that mediate interactions with these LN domains, mAbs specific for individual beta 1 heterodimers in human cells were used to study JAR cell interactions with LN and its fragments. An anti-alpha 6/beta 1-specific mAb, GoH3, virtually eliminated cell attachment to E8 and partially inhibited attachment to E1 and intact LN. Thus the major alpha 6/beta 1 attachment domain is present in fragment E8. An alpha 1/beta 1-specific mAb (S2G3) strongly inhibited cell attachment to collagen IV and partially inhibited JAR attachment to LN fragment E1. Thus, the alpha 1/beta 1 heterodimer is a dual receptor for collagen IV and LN, interacting with LN at a site in fragment E1. In combination, the anti-alpha 1- and anti-alpha 6-specific antibodies completely inhibited JAR cell attachment to LN and fragment E1. Thus, the alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers each function as LN receptors and act together to mediate the interactions of human JAR choriocarcinoma cells with LN

Global three-dimensional flow of a neutron superfluid in a spherical shell in a neutron star

We integrate for the first time the hydrodynamic Hall-Vinen-Bekarevich-Khalatnikov equations of motion of a $^{1}S_{0}$-paired neutron superfluid in a rotating spherical shell, using a pseudospectral collocation algorithm coupled with a time-split fractional scheme. Numerical instabilities are smoothed by spectral filtering. Three numerical experiments are conducted, with the following results. (i) When the inner and outer spheres are put into steady differential rotation, the viscous torque exerted on the spheres oscillates quasiperiodically and persistently (after an initial transient). The fractional oscillation amplitude ($\sim 10^{-2}$) increases with the angular shear and decreases with the gap width. (ii) When the outer sphere is accelerated impulsively after an interval of steady differential rotation, the torque increases suddenly, relaxes exponentially, then oscillates persistently as in (i). The relaxation time-scale is determined principally by the angular velocity jump, whereas the oscillation amplitude is determined principally by the gap width. (iii) When the mutual friction force changes suddenly from Hall-Vinen to Gorter-Mellink form, as happens when a rectilinear array of quantized Feynman-Onsager vortices is destabilized by a counterflow to form a reconnecting vortex tangle, the relaxation time-scale is reduced by a factor of $\sim 3$ compared to (ii), and the system reaches a stationary state where the torque oscillates with fractional amplitude $\sim 10^{-3}$ about a constant mean value. Preliminary scalings are computed for observable quantities like angular velocity and acceleration as functions of Reynolds number, angular shear, and gap width. The results are applied to the timing irregularities (e.g., glitches and timing noise) observed in radio pulsars.Comment: 6 figures, 23 pages. Accepted for publication in Astrophysical Journa

Anomalous Hall effect in superconductors with spin-orbit interaction

We calculate the anomalous Hall conductance of superconductors with spin-orbit interaction and with either uniform or local magnetization. In the first case we consider a uniform ferromagnetic ordering in a spin triplet superconductor, while in the second case we consider a conventional s-wave spin singlet superconductor with a magnetic impurity (or a diluted set of magnetic impurities). In the latter case we show that the anomalous Hall conductance can be used to track the quantum phase transition, that occurs when the spin coupling between the impurity and electronic spin density exceeds a certain critical value. In both cases we find that for large spin-orbit coupling the superconductivity is destroyed and the Hall conductance oscillates strongly.Comment: 10 pages, 6 figure

General energy bounds for systems of bosons with soft cores

We study a bound system of N identical bosons interacting by model pair potentials of the form V(r) = A sgn(p)r^p + B/r^2, A > 0, B >= 0. By using a variational trial function and the `equivalent 2-body method', we find explicit upper and lower bound formulas for the N-particle ground-state energy in arbitrary spatial dimensions d > 2 for the two cases p = 2 and p = -1. It is demonstrated that the upper bound can be systematically improved with the aid of a special large-N limit in collective field theory

Bacterial Cholangitis, Cholecystitis, or both in Dogs

BACKGROUND: Bacterial cholangitis and cholecystitis are rarely reported, poorly characterized diseases in the dog. OBJECTIVES: To characterize the clinical features of these conditions. ANIMALS: Twenty‐seven client‐owned dogs with bacterial cholangitis, cholecystitis, or both. METHODS: Multicenter, retrospective cases series of dogs with bacterial cholangitis, cholecystitis, or both, presenting January 2000 to June 2011 to 4 Veterinary Schools in Ireland/United Kingdom. Interrogation of hospital databases identified all cases with the inclusion criteria; histopathologically confirmed cholangitis or cholecystitis and bile culture/cytology results supporting a bacterial etiology. RESULTS: Twenty‐seven dogs met the inclusion criteria with approximately 460 hepatitis cases documented over the same study period. Typical clinical pathology findings were increases in liver enzyme activities (25/26), hyperbilirubinemia (20/26), and an inflammatory leukogram (21/24). Ultrasound findings, although nonspecific, aided decision‐making in 25/26 cases. The most frequent hepatobiliary bacterial isolates were Escherichia coli (n = 17; 16 cases), Enterococcus spp. (n = 8; 6 cases), and Clostridium spp. (n = 5; 5 cases). Antimicrobial resistance was an important feature of aerobic isolates; 10/16 E. coli isolates resistant to 3 or more antimicrobial classes. Biliary tract rupture complicated nearly one third of cases, associated with significant mortality (4/8). Discharged dogs had a guarded to fair prognosis; 17/18 alive at 2 months, although 5/10 re‐evaluated had persistent liver enzyme elevation 2–12 months later. CONCLUSION AND CLINICAL SIGNIFICANCE: Bacterial cholangitis and cholecystitis occur more frequently than suggested by current literature and should be considered in dogs presenting with jaundice and fever, abdominal pain, or an inflammatory leukogram or with ultrasonographic evidence of gallbladder abnormalities