Reference materials of catalytic activity as a means of ensuring the metrological traceability of measurement results. KATAL

Introduction. The article considers the problems of metrological support of catalytic activity measurements. The paper gives certain characteristics of the State Primary Special Measurement Standard for the unit of catalytic activity – KATAL and examines the role of reference materials (RMs) in ensuring the metrological traceability of measurement results.Materials and methods. A method for measuring the concentration of the recombinant protective antigen of Bacillus anthracis and the recombinant GP-protein of the Ebola virus, which means in using «sandwich» enzyme-linked immunosorbent assay, was certified by FGUP «VNIIMS» as a measurement procedure. The following RMs tested by FGUP «VNIIMS» can be used for the development and production of appropriate control samples when performing measurements for comparisons: the RM for the mass concentration of the recombinant protective antigen of Bacillus anthracis in phosphate-saline solution, the RM for the mass concentration of the recombinant GP-protein of the Ebola virus, and the RM for the mass concentration of recombinant Clostridium Difficile toxin.Results. The paper presents the main reactions of the method for measuring the catalytic activity of catalysts for heterogeneous processes, which are also used to carry out exhaust gas cleaning processes.Discussion and conclusions. Thus, conditions have been created for building hierarchies of calibrations of in-demand objects established on the basis of the List of Critical Technologies of the Russian Federation, state programs for the development of industrial sectors

Modern South Korean Historiography about the Phenomenon of Colonial Urbanization

The article was submitted on 8.05.2022.В разное время вопрос корейского колониального прошлого поднимался в работах многих российских исследователей, среди которых К. В. Асмолов, К. В. Иванов, А. Н. Ланьков, В. М. Тихонов и другие. Однако ни в одном из изученных авторами статьи трудов российских корееведов не рассматривается вопрос о корейских городах в колониальный период, развитие которых было одним из приоритетных направлений работы чиновников японской колониальной администрации. Особенно интересным это явление представляется в свете того, что и после освобождения Кореи, вплоть до 1960-х гг., основные положения городских планов, принятых еще колониальными властями, сохранялись и активно применялись. В статье рассматриваются основные тенденции и направления изучения феномена колониальной урбанизации в научных трудах представителей современной историографии Республики Корея, проанализированы основные направления в освещении реалий корейских городов в колониальный период, выявлены основные выводы наиболее заметных исследований, проведенных в Корее на современном этапе. Подвергнут анализу широкий круг работ южнокорейских исследователей, опубликованных преимущественно в специализированных журналах и других периодических изданиях, малоизвестных в России, определены ведущие направления южнокорейской историографии в изучении проблем развития корейских городов в колониальный период, позволяющих расширить представления о процессах, протекавших на Корейском полуострове в первой половине XX века. В этом смысле статья обладает существенным аспектом новизны.At various times, the issue of the Korean colonial past was raised in the works of many Russian researchers, including K. V. Ivanov, A. N. Lankov, V. M. Tikhonov, K. V. Asmolov and others. However, none of the works of Russian Korean scholars studied by the authors of the article deals with the issue of Korean cities in the colonial period, the development of which was one of the priority areas of work of officials of the Japanese colonial administration. This phenomenon is particularly interesting in the light of the fact that even after the liberation of Korea, up to the 1960s, the main provisions of the city plans adopted by the colonial authorities were preserved and actively applied. The article examines the main trends and directions of studying the phenomenon of colonial urbanization in the scientific works of representatives of modern historiography of the Republic of Korea, analyzes the main directions in the consecration of the realities of Korean cities in the colonial period, identifies the main conclusions of the most notable studies conducted in Korea at the present stage. The article analyzes a wide range of works by South Korean researchers published mainly in specialized journals and other periodicals that are little known in Russia, identifies the leading directions of South Korean historiography in the study of the problems of development of Korean cities during the colonial period, allowing to expand the understanding of the processes that took place on the Korean peninsula in the first half of the XX century. In this sense, the article has an essential aspect of novelty

Assessment of the psycho-emotional state of patients after COVID-19-associated pneumonia in relationship with laboratory indicators

The aim. To study peculiarities and association of psychological and laboratory indicators in patients with cardiovascular diseases (CVD) who underwent COVID-19 to clarify the factors affecting the possibility of developing delayed psychological and cardiovascular adverse events.Methods. The study enrolled 350 patients with COVID-19. Group 1 consisted of 92 patients without CVD, Group 2 – of 258 patients with CVD. Indicators of laboratory and psychological parameters were assessed according to the data of psychological questionnaire using GAD-7 (General Anxiety Disorder-7), PHQ-9 (Patient Health Questionnaire-9), PSS (Perceived Stress Scale) screening scales and SF-36. Parameters of complete blood count and biochemical blood tests were measured during hospitalization and three months after discharge from the monohospital.Results. After three months, in the general group of patients, signs of anxiety and depression were detected in more than 30 % of the examined patients, signs of stress – in 10.4 %. In the group with CVD, psycho-emotional disorders were identified in 1/4 of the patients, and severe stress – in 8 % of those included in the study. In addition, it was registered that the indicators of erythrocyte sedimentation rate, fibrinogen, high-sensitivity C-reactive protein (CRP), homocysteine and IL-6 remained at a higher level in the second group.Correlation analysis showed that the psychological component of health is interconnected with the level of neutrophils (p = 0.044) and fibrinogen (p = 0.050); the physical component of health is correlated with the level of erythrocytes (p = 0.030), hemoglobin (p = 0.015), CRP (p = 0.002), creatine phosphokinase (p = 0.036) and glucose (p = 0.017). Regression analysis revealed that in patients with CVD three months after hospitalization, an increased glucose index contributes to deterioration, and increased hematocrit and mean hemoglobin concentration improve the quality of life of patients.Conclusion. Laboratory markers that maintain the duration of a prolonged vascular reaction, violation of the rheological and metabolic properties of blood, determine the nature of the development of both psychological and cardiovascular complications

Стандартные образцы каталитической активности как средство обеспечения метрологической прослеживаемости результатов измерений. КАТАЛ

Introduction. The article considers the problems of metrological support of catalytic activity measurements. The paper gives certain characteristics of the State Primary Special Measurement Standard for the unit of catalytic activity – KATAL and examines the role of reference materials (RMs) in ensuring the metrological traceability of measurement results.Materials and methods. A method for measuring the concentration of the recombinant protective antigen of Bacillus anthracis and the recombinant GP-protein of the Ebola virus, which means in using «sandwich» enzyme-linked immunosorbent assay, was certified by FGUP «VNIIMS» as a measurement procedure. The following RMs tested by FGUP «VNIIMS» can be used for the development and production of appropriate control samples when performing measurements for comparisons: the RM for the mass concentration of the recombinant protective antigen of Bacillus anthracis in phosphate-saline solution, the RM for the mass concentration of the recombinant GP-protein of the Ebola virus, and the RM for the mass concentration of recombinant Clostridium Difficile toxin.Results. The paper presents the main reactions of the method for measuring the catalytic activity of catalysts for heterogeneous processes, which are also used to carry out exhaust gas cleaning processes.Discussion and conclusions. Thus, conditions have been created for building hierarchies of calibrations of in-demand objects established on the basis of the List of Critical Technologies of the Russian Federation, state programs for the development of industrial sectors.Введение. В данной статье рассматриваются вопросы метрологического обеспечения измерений каталитический активности. Приведены характеристики Государственного первичного специального эталона единицы каталитической активности – КАТАЛ. Рассмотрена роль стандартных образцов в обеспечении метрологической прослеживаемости результатов измерений.Материалы и методы. Метод измерений концентрации рекомбинантного протективного антигена Bacillus anthracis и рекомбинантного белка GP вируса Эбола, заключающийся в использовании «сэндвич» варианта иммуноферментного анализа, аттестован ФГУП «ВНИИМС» в качестве методики измерений. Испытанные ФГУП «ВНИИМС» стандартные образцы массовой концентрации рекомбинантного протективного антигена Bacillus anthracis в фосфатно-солевом растворе, массовой концентрации рекомбинантного белка GP вируса Эбола и массовой концентрации рекомбинантного токсина Clostridium Difficile могут применяться для разработки и производства соответствующих контрольных образцов, при проведении измерений для сличений.Результаты исследования. Приведены основные реакции метода измерений каталитической активности катализаторов гетерогенных процессов, которые применяются и для осуществления процессов очистки выхлопных газов.Обсуждения и заключения. Таким образом, созданы условия для построения иерархий калибровок востребованных объектов, установленных на основе Перечня критических технологий Российской Федерации, государственных программ развития отраслей промышленности

Токсикологическая характеристика Максаквина

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Мотивация толерантности в условиях вынужденной миграции

In the article the problem of motivation of tolerance in conditions of forced migration is discussed. The factors and the stages of migrants’ integration in the socio-labour relations of the recipient country are analyzed. The concept of tolerance instrumentalization as a formation process of tolerant attitudes towards foreigners is discussedВ статье рассматривается проблема мотивации толерантности в условиях вынужденной миграции населения. Анализируются факторы и этапы интеграции мигрантов в социально-трудовые отношения страны-реципиента. Рассматривается понятие инструментализации толерантности как процесса формирования терпимого отношения к иностранцам

Optical and chromatographic methods for efficiency analysis of non-stationary production

The problem of cost-effective oil production from carbonate reservoirs becomes more and more important every year due to a decrease in oil reserves in terrigenous reservoirs. Oil extraction from carbonate reservoirs is always associated with the low filtration properties of the rock matrix and the dense fracture network presence. One of the most effective methods at this development stage for carbonate reservoirs is the non-stationary drainage technology. The development of non-stationary deposit drainage technology by determining the effective action time with different work periods and well accumulation, due to deformations in the fracture system, will allow reducing wells watering percentage. As a result of fluid flows redistribution in the formation, unprocessed areas are attracted by capillary impregnation. An important stage in the application of non-stationary action is the study of oil optical properties. To assess the quality of the reserves involved in the development, laboratory studies of the deposit non-stationary production efficiency of the Romashkinskoye oil field were carried out. The investigations were carried out using a spectrophotometer and a chromatograph. The influence of non-stationary selection on the wells operation dynamics and on the final ORC was determined

CHANGE OF ARRHYTHMIC EVENTS IN ACUTE MYOCARDIAL INFARCTION WITH ST-SEGMENT ELEVATION AFTER PHARMACOINVASIVE REVASCULARIZATION

Aim. To study changes in course of arrhythmias, depending on the efficacy of coronary blood flow restoration due to pharmacoinvasive revascularization in patients with ST segment elevation myocardial infarction (STEMI).Material and methods. STEMI-patients (n=117) with an effective (according to ECG criteria) thrombolytic therapy (TLT) and the subsequent (after 3-24 hours) percutaneous coronary  intervention (PCI), were included into the study. Telemetry ECG was performed before  and after PCI with analysis of the arrhythmias and cardiac conduction disorders.Results. Patients (n=84; 71.8%) with an effective TLT, confirmed by the coronary angiography (CAG), and with subsequent effective PCI were included into the group "without rethrombosis" (RT(–)). Patients (n=33; 28.2%) with CAG proven rethrombosis of the infarct-related coronary artery and subsequent effective PCI were included into the group "with rethrombosis" (RT(+)). Regardless of the stability of coronary blood flow restoration after the TLT, PCI was associated with an increased incidence of ventricular tachycardia (VT) (p<0.01), sinus tachycardia (p=0.01), paroxysmal supraventricular tachycardia (SVT) (p<0.05) and paired ventricular extrasystoles (p<0.01). Compared to the RT(–) group, in the RT(+) group after PCI VT were recorded more frequently (44% vs 63.6%, respectively; p<0.05) as well as AV-block 3 degree (3.6% vs 12.1%, respectively; p<0.05). Episodes of sinus tachycardia were detected significantly more frequently before PCI in RT(–) group compared with RT(+) group (67.9% vs 45.4% respectively; p<0.01). The number of patients with episodes of sinus bradycardia increased (from 19% to 32.1%; p=0.02) after PCI in RT(–) group.Conclusion. The incidence of VT and SVT paroxysms, episodes of sinus tachycardia, atrioventricular conduction disturbances and ventricular extrasystoles increased in all patients after the effective PCI due to reperfusion. However, VT episodes and paroxysmal atrioventricular block grade 3 were more common in patients with previous re-thrombosis of the infarct-related coronary artery. Considering a high risk of arrhythmic events, continuous ECG mon itoring with automated alarm systems  about life-threatening arrhythmias should be applied in STEMI patients regardless of tactics of coronary  blood flow restoration and the reperfusion effectiveness

The partnership of government, society and universities in the process of education quality assurance: the experience of France

The paper deals with the specific features of higher education quality assurance in France based on the development of partnership between government, universities and independent agencies. The information about the two independent agencies providing assessment ofeducation quality – AERES and CTI is presented. The results of comparative analysis of Russian and French quality assurance systems in education are discussed with the aim to study the possibility of foreign experience transformation into the practice of Russian universities