1,506 research outputs found
1.5V fully programmable CMOS Membership Function Generator Circuit with proportional DC-voltage control
A Membership Function Generator Circuit (MFGC) with bias supply of 1.5 Volts and independent DC-voltage programmable functionalities is presented. The realization is based on a programmable differential current mirror and three compact voltage-to-current converters, allowing continuous and quasi-linear adjustment of the center position, height, width and slopes of the triangular/trapezoidal output waveforms. HSPICE simulation results of the proposed circuit using the parameters of a double-poly, three metal layers, 0.5 μm CMOS technology validate the functionality of the proposed architecture, which exhibits a maximum deviation of the linearity in the programmability of 7 %
Characterization of neutrino signals with radiopulses in dense media through the LPM effect
We discuss the possibilities of detecting radio pulses from high energy
showers in ice, such as those produced by PeV and EeV neutrino interactions. It
is shown that the rich radiation pattern structure in the 100 MHz to few GHz
allows the separation of electromagnetic showers induced by photons or
electrons above 100 PeV from those induced by hadrons. This opens up the
possibility of measuring the energy fraction transmitted to the electron in a
charged current electron neutrino interaction with adequate sampling of the
angular distribution of the signal. The radio technique has the potential to
complement conventional high energy neutrino detectors with flavor information.Comment: 5 pages, 4 ps figures. Submitted to Phys. Rev. Let
Development of alginate beads for probiotic encapsulation: influence of different parameters in the beads size
In the present study different parameters were evaluated in the formation of alginate beads by
ionotropic gelation (external extrusion). The size of alginate beads was determined and
results showed that needle-CaCl2 solution distance, flow rate, sodium alginate concentration,
needle diameter and molecular weight of sodium alginate influenced alginate beads
formation. Moreover, was concluded that needle diameter was the parameter that most
influenced the beads mean size
Observation of the Askaryan Effect: Coherent Microwave Cherenkov Emission from Charge Asymmetry in High Energy Particle Cascades
We present the first direct experimental evidence for the charge excess in
high energy particle showers predicted nearly 40 years ago by Askaryan. We
directed bremsstrahlung photons from picosecond pulses of 28.5 GeV electrons at
the SLAC Final Focus Test Beam facility into a 3.5 ton silica sand target,
producing electromagnetic showers several meters long. A series of antennas
spanning 0.3 to 6 GHz were used to detect strong, sub-nanosecond radio
frequency pulses produced whenever a shower was present. The measured electric
field strengths are consistent with a completely coherent radiation process.
The pulses show 100% linear polarization, consistent with the expectations of
Cherenkov radiation. The field strength versus depth closely follows the
expected particle number density profile of the cascade, consistent with
emission from excess charge distributed along the shower. These measurements
therefore provide strong support for experiments designed to detect high energy
cosmic rays and neutrinos via coherent radio emission from their cascades.Comment: 10 pages, 4 figures. Submitted to Phys. Rev. Let
Neutrino Induced Upward Going Muons from a Gamma Ray Burst in a Neutrino Telescope of Km^2 Area
The number of neutrino induced upward going muons from a single Gamma Ray
Burst (GRB) expected to be detected by the proposed kilometer scale IceCube
detector at the South Pole location has been calculated. The effects of the
Lorentz factor, total energy of the GRB emitted in neutrinos and its distance
from the observer (red shift) on the number of neutrino events from the GRB
have been examined. The present investigation reveals that there is possibility
of exploring the early Universe with the proposed kilometer scale IceCube
neutrino telescope.Comment: 18pages, 5 figures. Physical Review D in pres
On the energy determination of extensive air showers through the fluorescence technique
The determination of the shower development in air using fluorescence yield
is subject to corrections due to the angular spread of the particles in the
shower. This could introduce systematic errors in the energy determination of
an extensive air shower through the fluorescence technique.Comment: 4 pages, 2 figure
Radio-Frequency Measurements of Coherent Transition and Cherenkov Radiation: Implications for High-Energy Neutrino Detection
We report on measurements of 11-18 cm wavelength radio emission from
interactions of 15.2 MeV pulsed electron bunches at the Argonne Wakefield
Accelerator. The electrons were observed both in a configuration where they
produced primarily transition radiation from an aluminum foil, and in a
configuration designed for the electrons to produce Cherenkov radiation in a
silica sand target. Our aim was to emulate the large electron excess expected
to develop during an electromagnetic cascade initiated by an ultra high-energy
particle. Such charge asymmetries are predicted to produce strong coherent
radio pulses, which are the basis for several experiments to detect high-energy
neutrinos from the showers they induce in Antarctic ice and in the lunar
regolith. We detected coherent emission which we attribute both to transition
and possibly Cherenkov radiation at different levels depending on the
experimental conditions. We discuss implications for experiments relying on
radio emission for detection of electromagnetic cascades produced by ultra
high-energy neutrinos.Comment: updated figure 10; fixed typo in equation 2.2; accepted by PR
Impact of adherence on growth response during the first 2 years of growth hormone treatment
Purpose
Adherence to growth hormone (GH) treatment impacts clinical outcomes. The aim of this study is to assess the impact of adherence to rhGH treatment (2 years) on auxological outcomes.
Methods
Multicentric, retrospective observational study in rhGH-naive GHD/SGA children treated with Saizen (R) during >= 2 years. Growth response was assessed by evaluating the change in height standard deviation score (Delta H SDS) and the index of responsiveness (IoR). Adherence was monitored using EasyPod (TM) Connect device.
Results
A total of 110 patients (3 Spanish centers) were evaluable (GHD n = 76, SGA n = 34). Adherence was 95.6 and 93.9% (year 1, 2). SGA and GHD children showed an increase of 0.6 cm/year and 1.1 cm/year for each 10% adherence modification. Lower adherence was observed in patients with lower pretreatment height velocity (HV) and in patients whose parents had a lower level of education. A positive correlation between index of responsiveness (IoR) during the first and second years with HV SDS during the second year and between IoR2 and adherence (year 1, 2) was observed. The frequency of patients with HV > 1 SD was higher (p = 0.025) among patients with adherence >90%. The best model to predict the height gain(cm) reaching an adjusted R squared of 0.489 involved percentage of adherence, Tanner stage, pretreatment HV, dose of rhGH, and whether the treatment was initiated before or after puberty.
Conclusions
Adherence during the first 2 years of response was very high >90% and showed a negative association with age, pretreatment HV and treatment duration and a positive correlation with the level of parent education
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