992 research outputs found
Book Review: Champions for Peace: Women Winners of the Nobel Peace Prize
Review of Champions for Peace: Women Winners of the Nobel Peace Prize by Judith Hicks Stieh
Tagging single muons and other long-flying relativistic charged particles by ultra-fast timing in air Cherenkov telescopes
Atmospheric air Cherenkov telescopes are successfully used for ground-based,
very high-energy (VHE) gamma ray astronomy. Triggers from the so-called single
muon and other long-flying relativistic charged particle events are an unwanted
background for the Cherenkov telescope. Because of low rate at TeV energies the
muon background is unimportant. It is much more intense for telescopes with
high photon sensitivity and low energy threshold. Below a few hundred GeV
energy, the so-called muon background becomes so intense, that it can
deteriorate the sensitivity of telescopes (the so-called muon-wall problem).
From general considerations it can be anticipated that the signature of these
particles should be a light pulse with a narrow time structure. In fact,
simulations show that the pulses from muons have a very narrow time profile
that is well below the time resolutions of nearly all currently operating
telescopes. In this report we elaborate on the time profile of Cherenkov light
from the so-called single muons and show that a telescope with ultra-fast time
response can open a new dimension allowing one to tag and to reject those
events.Comment: Accepted by Astroparticle Physic
Neural correlates of emotion word processing: the complex relation between emotional valence and arousal
Poster Session 1: no. 2The Conference's website is located at http://events.unitn.it/en/psb2010Emotion is characterised by a two-dimensional structure: valence describes the extent to which an emotion is positive or negative, whereas arousal refers to the intensity of an emotion, how exciting or calming it is. Emotional content of verbal material influences cognitive processing during lexical decision, naming, emotional Stroop task and many others.
Converging findings showed that emotionally valenced words (positive or negative) are processed faster than neutral words, as shown by reaction time and ERP measures, suggesting a prioritisation of emotional …published_or_final_versio
EXAMINING THE RELATIONSHIP BETWEEN INCLUSIVITY AND WELL-BEING IN THE GENDER, SEXUAL, AND ROMANTIC MINORITY COMMUNITY
Research has established that higher levels of inclusivity promote increased levels of well-being in GSRM populations (Yoder & Mattheis, 2016); however, there is a lack of research exploring a moderating effect of psychological flexibility on this relationship. Previous research has also demonstrated that psychological flexibility is related to increased quality of life (Walloch & Hill, 2016); however, the relationship between psychological flexibility and inclusivity remains largely unexplored in GSRM populations. The purpose of this study was to explore how inclusivity, psychological distress, and psychological flexibility correlate with well-being among a sample of 198 individuals who identify as GSRM. This study found that individuals who identified as having high social inclusion experienced fewer negative impacts on their well-being while individuals with high levels of distress had more negative impacts on their well-being. It was also found that individuals who indicated greater amounts of psychological inflexibility had more negative impacts on well-being. This study did not find distress to vary significantly as a function of psychological flexibility, which is not consistent with the findings of other studies (Flynn & Bhambhani, 2021). Limitations to this study are explored, including the potential effect of the COVID-19 pandemic on participants. This research was conducted to understand how employers, organizations, and institutions can better address the needs of GSRM individuals
Detection of Cherenkov light from air showers with Geiger-APDs
We have detected Cherenkov light from air showers with Geiger-mode APDs
(G-APDs). G-APDs are novel semiconductor photon-detectors, which offer several
advantages compared to conventional photomultiplier tubes in the field of
ground-based gamma-ray astronomy. In a field test with the MAGIC telescope we
have tested the efficiency of a G-APD / light catcher setup to detect Cherenkov
light from air showers. We estimate a detection efficiency, which is 60% higher
than the efficiency of a MAGIC camera pixel. Ambient temperature dark count
rates of the tested G-APDs are below the rates of the night sky light
background. According to these recent tests G-APDs promise a major progress in
ground-based gamma-ray astronomy.Comment: 4 pages, 5 figures, to appear in the proceedings of the 30th
International Cosmic Ray Conference, Merida, July 200
Inhibition and language processing deficits in different types of aphasia
INTRODUCTION: The relation between executive control and language processing deficits in aphasia need further investigation (Murray, 2012; McNeil & Hula , 2008). It has been shown that language comprehension difficulties are associated with impaired inhibition (Martin & Allen, 2008). The current study had three main objectives: (1) to measure inhibition deficit in adults with fluent and nonfluent aphasia as well as in the healthy controls; (2) to investigate the ...postprin
Physioxia promotes the articular chondrocyte-like phenotype in human chondroprogenitor-derived self-organized tissue
Introduction: Biomaterial-based tissue engineering has not successfully reproduced the structural architecture or functional mechanical properties of native articular cartilage. In scaffold-free tissue engineering systems, cells secrete and organize the entire extracellular matrix over time in response to environmental signals such as oxygen level. In this study, we investigated the effect of oxygen on the formation of neocartilage from human-derived chondrogenic cells.
Materials and Methods: Articular chondrocytes (ACs) and articular cartilage progenitor cells (ACPs) derived from healthy human adults were guided toward cell condensation by centrifugation onto plate inserts that were uncoated or coated with either agarose or fibronectin. Neocartilage discs were cultured at hyperoxic (20%) or physioxic (5%) oxygen levels, and biochemical, biomechanical, and molecular analyses were used to compare the cartilage produced by ACs versus ACPs.
Results: Fibronectin-coated inserts proved optimal for growing cartilaginous discs from both cell types. In comparison with culture in hyperoxia, AC neocartilage cultured at physioxia exhibited a significant increase in chondrogenic gene expression, proteoglycan production, and mechanical properties with a concomitant decrease in collagen content. At both oxygen levels, ACP-derived neocartilage produced tissue with significantly enhanced mechanical properties and collagen content relative to AC-derived neocartilage. Both ACs and ACPs produced substantial collagen II and reduced levels of collagens I and X in physioxia relative to hyperoxia. Neocartilage from ACPs exhibited anisotropic organization characteristic of native cartilage with respect to collagen VI of the pericellular matrix when compared with AC-derived neocartilage; however, only ACs produced abundant surface-localized lubricin.
Discussion and Conclusions: Guiding human-derived cells toward condensation and subsequent culture in physioxia promoted the articular cartilage tissue phenotype for ACs and ACPs. Unlike ACs, ACPs are clonable and highly expandable while retaining chondrogenicity. The ability to generate large tissues utilizing a scaffold-free approach from a single autologous progenitor cell may represent a promising source of neocartilage destined for cartilage repair
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