Supersymmetric methods in the traveling variable: inside neurons and at the brain scale

We apply the mathematical technique of factorization of differential operators to two different problems. First we review our results related to the supersymmetry of the Montroll kinks moving onto the microtubule walls as well as mentioning the sine-Gordon model for the microtubule nonlinear excitations. Second, we find analytic expressions for a class of one-parameter solutions of a sort of diffusion equation of Bessel type that is obtained by supersymmetry from the homogeneous form of a simple damped wave equations derived in the works of P.A. Robinson and collaborators for the corticothalamic system. We also present a possible interpretation of the diffusion equation in the brain contextComment: 14 pages, 1 figur

Multifractal properties of elementary cellular automata in a discrete wavelet approach of MF-DFA

In 2005, Nagler and Claussen (Phys. Rev. E 71 (2005) 067103) investigated the time series of the elementary cellular automata (ECA) for possible (multi)fractal behavior. They eliminated the polynomial background at^b through the direct fitting of the polynomial coefficients a and b. We here reconsider their work eliminating the polynomial trend by means of the multifractal-based detrended fluctuation analysis (MF-DFA) in which the wavelet multiresolution property is employed to filter out the trend in a more speedy way than the direct polynomial fitting and also with respect to the wavelet transform modulus maxima (WTMM) procedure. In the algorithm, the discrete fast wavelet transform is used to calculate the trend as a local feature that enters the so-called details signal. We illustrate our result for three representative ECA rules: 90, 105, and 150. We confirm their multifractal behavior and provide our results for the scaling parametersComment: 8 pages, 5 figures, 21 reference

Multifractal properties of elementary cellular automata in a discrete wavelet approach of MF-DFA

In 2005, Nagler and Claussen (Phys. Rev. E 71 (2005) 067103) investigated the time series of the elementary cellular automata (ECA) for possible (multi)fractal behavior. They eliminated the polynomial background at^b through the direct fitting of the polynomial coefficients a and b. We here reconsider their work eliminating the polynomial trend by means of the multifractal-based detrended fluctuation analysis (MF-DFA) in which the wavelet multiresolution property is employed to filter out the trend in a more speedy way than the direct polynomial fitting and also with respect to the wavelet transform modulus maxima (WTMM) procedure. In the algorithm, the discrete fast wavelet transform is used to calculate the trend as a local feature that enters the so-called details signal. We illustrate our result for three representative ECA rules: 90, 105, and 150. We confirm their multifractal behavior and provide our results for the scaling parametersComment: 8 pages, 5 figures, 21 reference

Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with Disseminated Mycobacterium avium-intracellulare Infection

Actinomyces and Mycobacterium avium-intracellulare are facultative intracellular organisms, members of the bacterial order actinomycetales. Although Actinomyces can behave as copathogen when anatomic barriers are compromised, its coinfection with Mycobacterium avium-intracellulare has not previously been reported. We present the first reported case of palatal actinomycosis co-infection with disseminated MAC, in an HIV-infected subject with Kaposi sarcoma and diabetes. We discuss the pathogenesis of the complex condition of this subject

Analysis of temporomandibular joint dysfunction in paediatric patients with unilateral crossbite using automatically generated finite element models

The evaluation of temporomandibular joint (TMJ) dysfunction using finite element models is a time consuming process that requires extensive technical knowledge. We combined a statistical active appearance model with automated modelling algorithms to biomechanically study the relationship between TMJ malformations and dysfunction in radiographs from 20 paediatric patients with unilateral crossbite. A fitting algorithm (fitting error < 4%) recognised the TMJ shape and adjusted the dimensions of each patient-specific 2D FE model, which was then used to compute 2 different joint movements. Significant functional differences were observed between the crossbite and non-cross bite sides, and the shape-function relation was verified

Regulation of the Immune Response in Cysticercosis: Lessons from an Old Acquainted Infection

In the last decades, we have learned some critical lessons about the relationship between the human body and its interaction with many infectious diseases, where regularly, the immune system has a major role in protection. We learned to differentiate between the immune response occurring in either an intracellular or extracellular parasitic infection, between innate and adaptive immune response, between either inflammatory or anti-inflammatory responses, and finally, we learned to recognize very particular mechanisms, such as the inability of the immune system to respond during very particular scenarios, such as the inability of T cells to both proliferate and produce cytokines even after their exposure to mitogens or specific-antigens. Along with our increase in the knowledge in immunology, we figured out that immunoregulation and immunosuppression are processes used by many parasites to reduce the capacity of the immune system to eliminate them, and to persist in the host favoring their transmission and also to complete their life cycles. Immunoregulation involves several mechanisms such as anergy, apoptosis, induction of both suppressive cytokines and membrane-bound molecules, as well as specialized cell populations of the immune system like regulatory T cells, Alternative Activated Macrophages, or Myeloid-derived Suppressor Cells, that together modify the outcome of the immune response. In this chapter we will review the general differences between the different types of immunoregulation, the kind of cellular populations of the immune system used by the helminths Taenia solium and Taenia crassiceps to induce immunoregulation and immunosuppression and also, the mechanisms used by these parasites such as mimicking molecules of the immune system to replace directly these mechanisms. Understanding and deciphering all these regulatory mechanisms could be useful to develop new tools to control this infection

SEEMP: A Semantic Interoperability Infrastructure for e-government services in the employment sector

This paper presents SEEMP, a marketplace to coordinate and integrate public and private employment services (ESs) around the EU Member States. The need for flexible collaboration in the marketplace gives rise to the issue of interoperability in both data exchange and share of services. SEEMP proposes a mixed approach that relies on the concepts of services and semantics. SEEMP approach combines Software Engineering and Semantic Web methodologies/tools in an infrastructure that allows for a meaningful service-based communication among ESs

Выход загруженных веществ in vitro из системы упорядоченных биодеградируемых отдельностоящих микрокамер

We address in this paper the optimization of a multi-site, multi-period, and multi-product planning problem with sequence-dependent changeovers, which is modeled as a mixed-integer linear programming (MILP) problem. Industrial instances of this problem require the planning of a number of production and distribution sites over a time span of several months. Temporal and spatial Lagrangean decomposition schemes can be useful for solving these types of large-scale production planning problems. In this paper we present a theoretical result on the relative size of the duality gap of the two decomposition alternatives. We also propose a methodology for exploiting the economic interpretation of the Lagrange multipliers to speed the convergence of numerical algorithms for solving the temporal and spatial Lagrangean duals. The proposed methods are applied to the multi-site multi-period planning problem in order to illustrate their computational effectiveness.</p

The SEEMP Approach to Semantic Interoperability for E-Employment

SEEMP is a European Project that promotes increased partnership between labour market actors and the development of closer relations between private and public employment services, making optimal use of the various actors’ specific characteristics, thus providing job-seekers and employers with better services. The need for a flexible collaboration gives rise to the issue of interoperability in both data exchange and share of services. SEEMP proposes a solution that relies on the concepts of services and semantics in order to provide a meaningful service-based communication among labour market actors requiring a minimal shared commitment