145 research outputs found

    Changes in Adolescent Birth Rates within Appalachian Subregions and Non-Appalachian Counties in the United States, 2012–2018

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    Background: Adolescent births are associated with numerous challenges. While adolescent birth rates have declined across the U.S., disparities persist and little is known about the extent to which broader declines are seen within Appalachia. Purpose: The purpose of this study was to examine the extent to which adolescent birth rates have declined across the subregions of Appalachia relative to non-Appalachia. Methods: We conducted a retrospective study of adolescent birth rates between 2012 and 2018 using county-level vital records data. Differences were examined across the subregions of Appalachia and among non-Appalachian counties. Multiple regression models were used to examine changes in the rate of decline over time, adjusting for additional covariates of relevance. Results: About 13.4% of all counties in the U.S. are within the Appalachian region. The rate of adolescent births decreased by 12.6 adolescent births per 1,000 females between 2012 and 2018 across the U.S. While all regions experienced declines in the rate of adolescent births, Central Appalachia had the largest reduction in adolescent births (18.5 per 1,000 females), which was also noted in the adjusted models when compared to the counties of non-Appalachia (b= –5.78, CI: –9.58, –1.97). Rates of adolescent birth were markedly higher in counties considered among the most socially and economically vulnerable. Implications: This study demonstrates that the rates of adolescent births vary across the subregions of Appalachia but have declined proportional to rates in non-Appalachia. While adolescent birth rates remain higher in select subregions of Appalachia compared to non-Appalachia, the gap has narrowed considerably

    The Future of Women\u27s Studies (Continued)

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    from the CALIFORNIA STATE UNIVERSITY, CHICO Women\u27s Studies at Chico developed from courses offered by women in their different departments, gathered to form a minor degree program in spring, 1973. Two specifically women\u27s studies courses were designed at that time: a team-taught Introduction to Women\u27s Studies (draws around 80 students a semester, changes women students\u27 expectations and horizons by projecting models of achieving women) and a Senior Research Seminar designed to integrate the students\u27 major and minor. Both are taught by the Women\u27s Studies Coordinator. Student demand has led to the development of new courses whose content received a great deal of student input: Women\u27s Health, Women in the Working World, Women in Art, Minority Women and the Re-Entry Program for Mature Women. There are now 20 courses offered through the Women\u27s Studies Program. Students are designing special degrees on the B.A. and M.A. level in areas such as Women and Counseling, Psychology and Art. ...from the CITY COLLEGE OF THE CITY UNIVERSITY OF NEW YORK... ...from FLORIDA INTERNATIONAL UNIVERSITY... ...from the JERSEY CITY STATE COLLEGE... ...from the UNIVERSITY OF MARYLAND... ...from UNIVERSITY OF MASSACHUSETTS/AMHERST... ...from the UNIVERSITY OF MINNESOTA... ...from the UNIVERSITY OF SOUTH FLORIDA..

    Activation of Central Melanocortin Pathways by Fenfluramlne

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    D-fenfluramine (d-FEN) was once widely prescribed and was among the most effective weight loss drugs, but was withdrawn from clinical use because of reports of cardiac complications in a subset of patients. Discerning the neurobiology underlying the anorexic action of d-FEN may facilitate the development of new drugs to prevent and treat obesity. Through a combination of functional neuroanatomy, feeding, and electrophysiology studies in rodents, we show that d-FEN-induced anorexia requires activation of central nervous system melanocortin pathways. These results provide a mechanistic explanation of d-FEN\u27s anorexic actions and indicate that drugs targeting these downstream melanocortin pathways may prove to be effective and more selective antiobesity treatments
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