31 research outputs found
Encoding a qubit into multilevel subspaces
We present a formalism for encoding the logical basis of a qubit into
subspaces of multiple physical levels. The need for this multilevel encoding
arises naturally in situations where the speed of quantum operations exceeds
the limits imposed by the addressability of individual energy levels of the
qubit physical system. A basic feature of the multilevel encoding formalism is
the logical equivalence of different physical states and correspondingly, of
different physical transformations. This logical equivalence is a source of a
significant flexibility in designing logical operations, while the multilevel
structure inherently accommodates fast and intense broadband controls thereby
facilitating faster quantum operations. Another important practical advantage
of multilevel encoding is the ability to maintain full quantum-computational
fidelity in the presence of mixing and decoherence within encoding subspaces.
The formalism is developed in detail for single-qubit operations and
generalized for multiple qubits. As an illustrative example, we perform a
simulation of closed-loop optimal control of single-qubit operations for a
model multilevel system, and subsequently apply these operations at finite
temperatures to investigate the effect of decoherence on operational fidelity.Comment: IOPart LaTeX, 2 figures, 31 pages; addition of a numerical simulatio
Quantum computing implementations with neutral particles
We review quantum information processing with cold neutral particles, that
is, atoms or polar molecules. First, we analyze the best suited degrees of
freedom of these particles for storing quantum information, and then we discuss
both single- and two-qubit gate implementations. We focus our discussion mainly
on collisional quantum gates, which are best suited for atom-chip-like devices,
as well as on gate proposals conceived for optical lattices. Additionally, we
analyze schemes both for cold atoms confined in optical cavities and hybrid
approaches to entanglement generation, and we show how optimal control theory
might be a powerful tool to enhance the speed up of the gate operations as well
as to achieve high fidelities required for fault tolerant quantum computation.Comment: 19 pages, 12 figures; From the issue entitled "Special Issue on
Neutral Particles
Speeding up the spatial adiabatic passage of matter waves in optical microtraps by optimal control
We numerically investigate the performance of atomic transport in optical
microtraps via the so called spatial adiabatic passage technique. Our analysis
is carried out by means of optimal control methods, which enable us to
determine suitable transport control pulses. We investigate the ultimate limits
of the optimal control in speeding up the transport process in a triple well
configuration for both a single atomic wave packet and a Bose-Einstein
condensate within a regime of experimental parameters achievable with current
optical technology.Comment: 17 pages, 14 figure
Therapeutic Management of Pseudomonas aeruginosa Bloodstream Infection Non-Susceptible to Carbapenems but Susceptible to âOldâ Cephalosporins and/or to Penicillins
It is unknown as to whether other beta-lactams can be used for bloodstream infections (BSI) resulting from Pseudomonas aeruginosa (PA) which are non-susceptible to one or more carbapenem. We conducted a retrospective cohort study at the Assaf Harofeh Medical Center (AHMC) from January 2010 to August 2014. Adult patients with PA-BSI non-susceptible to a group 2 carbapenem but susceptible to ceftazidime or piperacillin (with or without tazobactam), were enrolled. We compared the outcomes of patients who received an appropriate beta-lactam antibiotic (âcasesâ) to those who received an appropriate non-beta-lactam antibiotic (âcontrolsâ). Whole genome sequencing was performed for one of the isolates. Twenty-six patients with PA-BSI met inclusion criteria: 18 received a beta-lactam and 8 a non-beta-lactam (three a fluoroquinolone, two colistin, one a fluoroquinolone and an aminoglycoside, one a fluoroquinolone and colistin, and one colistin and an aminoglycoside). All clinical outcomes were similar between the groups. There were large variations in the phenotypic susceptibilities of the strains. A detailed molecular investigation of one isolate revealed a strain that belonged to MLST-137, with the presence of multiple efflux pumps, OXA-50, and a chromosomally mediated Pseudomonas-derived cephalosporinase (PDC). The oprD gene was intact. Non-carbapenem-ÎČ-lactams may still be effective alternatives for short duration therapy (up to 14 days) for BSI caused by a carbapenem non-susceptible (but susceptible to ceftazidime, piperacillin, and/or piperacillin-tazobactam) PA strain. This observation requires further confirmatory analyses. Future molecular investigations should be performed, in order to further analyze additional potential mechanisms for this prevalent phenotype