A caricature of a singular curvature flow in the plane

We study a singular parabolic equation of the total variation type in one dimension. The problem is a simplification of the singular curvature flow. We show existence and uniqueness of weak solutions. We also prove existence of weak solutions to the semi-discretization of the problem as well as convergence of the approximating sequences. The semi-discretization shows that facets must form. For a class of initial data we are able to study in details the facet formation and interactions and their asymptotic behavior. We notice that our qualitative results may be interpreted with the help of a special composition of multivalued operators

Lipopolysaccharides and outer membrane proteins as main structures involved in complement evasion strategies of non-typhoidal Salmonella strains

Non-typhoidal Salmonella (NTS) infections pose a serious public health problem. In addition to the typical course of salmonellosis, an infection with Salmonella bacteria can often lead to parenteral infections and sepsis, which are particularly dangerous for children, the elderly and immunocompromised. Bacterial resistance to serum is a key virulence factor for the development of systemic infections. Salmonella, as an enterobacterial pathogen, has developed several mechanisms to escape and block the antibacterial effects of the complement system. In this review, we discuss the relevance of outer membrane polysaccharides to the complement evasion mechanisms of NTS strains. These include the influence of the overall length and density of the lipopolysaccharide molecules, modifications of the O-antigen lipopolysaccharide composition and the role of capsular polysaccharides in opsonization and protection of the outer membrane from the lytic action of complement. Additionally, we discuss specific outer membrane protein complement evasion mechanisms, such as recruitment of complement regula-tory proteins, blocking assembly of late complement components to form the membrane attack complex and the proteolytic cleavage of complement proteins.Peer reviewe

Kinematics of Tycho-2 Red Giant Clump Stars

Based on the Ogorodnikov-Milne model, we analyze the proper motions of 95 633 red giant clump (RGC) stars from the Tycho-2 Catalogue. The following Oort constants have been found: A = 15.9+-0.2 km/s/kpc and B = -12.0+-0.2 km/s/kpc. Using 3632 RGC stars with known proper motions, radial velocities, and photometric distances, we show that, apart from the star centroid velocity components relative to the Sun, only the model parameters that describe the stellar motions in the XY plane differ significantly from zero. We have studied the contraction (a negative K-effect) of the system of RGC stars as a function of their heliocentric distance and elevation above the Galactic plane. For a sample of distant (500--1000 pc) RGC stars located near the Galactic plane (|Z|<200 pc) with an average distance of d=0.7 kpc, the contraction velocity is shown to be Kd= -3.5+-0.9 km/s; a noticeable vertex deviation, lxy = 9.1+-0.5 degrees, is also observed for them. For stars located well above the Galactic plane (|Z|>=200 pc), these effects are less pronounced, Kd = -1.7+-0.5 km/s and lxy = 4.9+-0.6 degrees. Using RGC stars, we have found a rotation around the Galactic X axis directed toward the Galactic center with an angular velocity of -2.5+-0.3 km/s/kpc, which we associate with the warp of the Galactic stellar-gaseous disk.Comment: 23 pages, 7 figures, 4 table

Potencial do cambuí (Myrciaria tenella) para a elaboração de fermentado.

O presente trabalho objetivou testar o potencial do cambuí, coletado de Morro do Chapéu-BA, para a elaboração de fermentado, como alternativa de agregação de valor para pequenos produtores extrativistas

A method to localize gamma-ray bursts using POLAR

The hard X-ray polarimeter POLAR aims to measure the linear polarization of the 50-500 keV photons arriving from the prompt emission of gamma-ray bursts (GRBs). The position in the sky of the detected GRBs is needed to determine their level of polarization. We present here a method by which, despite of the polarimeter incapability of taking images, GRBs can be roughly localized using POLAR alone. For this purpose scalers are attached to the output of the 25 multi-anode photomultipliers (MAPMs) that collect the light from the POLAR scintillator target. Each scaler measures how many GRB photons produce at least one energy deposition above 50 keV in the corresponding MAPM. Simulations show that the relative outputs of the 25 scalers depend on the GRB position. A database of very strong GRBs simulated at 10201 positions has been produced. When a GRB is detected, its location is calculated searching the minimum of the chi2 obtained in the comparison between the measured scaler pattern and the database. This GRB localization technique brings enough accuracy so that the error transmitted to the 100% modulation factor is kept below 10% for GRBs with fluence Ftot \geq 10^(-5) erg cm^(-2) . The POLAR localization capability will be useful for those cases where no other instruments are simultaneously observing the same field of view.Comment: 13 pages, 10 figure

Development of methodology for the determination of organic acids in must, grape juice and wine by high performance liquid chromatography (HPLC).

Resumo. IUFoST 2012