Modelling the variable broad-band optical/UV/X-ray spectrum of PG1211+143: Implications for the ionized outflow

We present the results from a detailed analysis of the 2007 Swift monitoring campaign of the quasar PG1211+143. We constructed broad-band, optical/UV/X-ray spectral energy distributions over three X-ray flux intervals. We fitted them with a model which accounts for the disc and the X-ray coronal emission and the warm absorber (well established in this source). The three flux spectra are well fitted by the model we considered. The disc inner temperature remains constant at ~2 eV, while X-rays are variable both in spectral slope and normalization. The absorber covers almost 90% of the central source. It is outflowing with a velocity less than 2.3*10^4 km/s (3sigma upper limit), and has a column density of ~10^23.2. Its ionization parameter varies by a factor of 1.6, and it is in photo-ionizing equilibrium with the ionizing flux. It is located at a distance of less than 0.35 pc from the central source and its relative thickness, DR/R is less than 0.1. The absorber' s ionization parameter variations can explain the larger than average amplitude of the X-ray variations. The absence of optical/UV variations (consistent with the high black hole mass estimate) argues against the presence of inward propagating disc fluctuations and strong X-ray illumination of the disc (in agreement with the low ratio of X-ray over the bolometric luminosity of ~20-35). We estimate an upper limit for the mass outflow of ~5 solar masses per year (~2.3 times the Eddington mass accretion rate). If the outflow rate is indeed that high, then it must be a short-lived episode in the quasar's life time. Finally, we estimate an upper limit for the kinetic power of the outflow of ~1.4*10^43 ergs/s. This outflow cannot deploy significant mechanical energy to the surrounding ISM of the quasar's host galaxy, but is sufficient to heat the ISM to 10^7 K and to produce a fast decline to the star formation rate of the galaxy.Comment: Accepted for publication by A&

A study of the entanglement in systems with periodic boundary conditions

We define the local periodic linking number, LK, between two oriented closed or open chains in a system with three-dimensional periodic boundary conditions. The properties of LK indicate that it is an appropriate measure of entanglement between a collection of chains in a periodic system. Using this measure of linking to assess the extent of entanglement in a polymer melt we study the effect of CReTA algorithm on the entanglement of polyethylene chains. Our numerical results show that the statistics of the local periodic linking number observed for polymer melts before and after the application of CReTA are the same.Comment: 11 pages, 11 figure

The strange-quark chemical potential as an experimentally accessible "order parameter" of the deconfinement phase transition for finite baryon-density

We consider the change of the strange-quark chemical potential in the phase diagram of nuclear matter, employing the Wilson loop and scalar quark condensate order parameters, mass-scaled partition functions and enforcing flavor conservation. Assuming the region beyond the hadronic phase to be described by massive, correlated and interacting quarks, in the spirit of lattice and effective QCD calculations, we find the strange-quark chemical potential to change sign: from positive in the hadronic phase - to zero upon deconfinement - to negative in the partonic domain. We propose this change in the sign of the strange-quark chemical potential to be an experimentally accessible order parameter and a unique, concise and well-defined indication of the quark-deconfinement phase transition in nuclear matter.Comment: 22 pages, 14 figures within text, 2 figures(6,B3) as separate files. To be published in J.Phys.G: Nucl.&Part.Phys. G28 (2002

Model of Centauro and strangelet production in heavy ion collisions

We discuss the phenomenological model of Centauro event production in relativistic nucleus-nucleus collisions. This model makes quantitative predictions for kinematic observables, baryon number and mass of the Centauro fireball and its decay products. Centauros decay mainly to nucleons, strange hyperons and possibly strangelets. Simulations of Centauro events for the CASTOR detector in Pb-Pb collisions at LHC energies are performed. The signatures of these events are discussed in detail.Comment: 19 pages, LaTeX+revtex4, 14 eps-figures and 3 table

Ethical and practical challenges in implementing informed consent in HIV/AIDS clinical trials in developing or resource-limited countries

Background/rationale: Ethical issues regarding HIV/AIDS human research in the developing world remain under continuous evaluation; a critical area of concern includes informed consent. This paper reviews several of the most important ethical and practical aspects of informed consent in HIV research in developing countries. Enhancement of overall understanding of such key issues might promote higher ethical standards of future research.Objectives: The major objective was to address informed consent in human research in non-Western societies, and specifically in HIV clinical trials of affected adults. Secondary end-points included the consent complexities in HIV research involving vulnerable patient populations in resource-limited nations, such as children, adolescents and women.Methods: A systematic review of the published literature using MEDLINE and EMBASE from 1998 until December 2008 was performed, using the search terms ‘HIV/AIDS’, ‘informed consent’, ‘clinical trials’, ‘developing world’.Results: Ethical complexities such as participants’ diminished autonomy, coercion or monetary inducement, language difficulties, illiteracy or lack of true understanding of the entire study, cultural barriers mainly due to communitarianism and social diversities were identified in the 44 studies reviewed. Informed consent of vulnerable patient populations must be tailored to their sex and developmental age, while counselling is fundamental. Children and adolescents’ assent must be ensured. Local language is to be used, while trusted community leaders and local cultural representatives may convey information.Discussion: Despite the heterogeneity of studies, similarities were  identified. Providing adequate and comprehensive information and assessing the true understanding of the research represent fundamental prerequisites. Potential solutions to the critical areas of concern include peer counselling and meetings with local community leaders or local cultural representatives. Conclusions: International investigators of HIV human research should bear in mind these ethical issues and their potential solutions, when trying to ensure ethical research conduct, based on a truly informed and culturally relevant consent

Physics at Very Small Angles with CASTOR at CMS

CASTOR is a small (56 cm diameter) quartz-tungsten Cerenkov calorimeter covering the small angles 0.2-0.6 deg (5.2<="eta"<=6.4) in CMS, a major experiment at the LHC. Particularly with heavy-ion reactions a substantial fraction of the total reaction energy goes into this large "eta" region. CASTOR will function as a part of CMS and also as an independent detector to search for special types of events in the far-forward region. It is divided into 16 azimuthal sectors, each with 18 longitudinal segments to allow identification of particles by their energy-loss profiles. The most forward segments are smaller to better characterize electromagnetic events

Revisiting UV/optical continuum time lags in AGN

In this paper, we present an updated version of our model (KYNXiltr) which considers thermal reverberation of a standard Novikov-Thorne accretion disc illuminated by an X-ray point-like source. Previously, the model considered only two cases of black hole spins, and assumed a colour correction factor $f_{\rm col} = 2.4$. Now, we extend the model to any spin value and colour correction. In addition, we consider two scenarios of powering the X-ray corona, either via accretion, or external to the accretion disc. We use KYNXiltr to fit the observed time lags obtained from intense monitoring of four local Seyfert galaxies (NGC 5548, NGC 4395, Mrk 817, and Fairall 9). We consider various combinations of black hole spin, colour correction, corona height, and fraction of accretion power transferred to the corona. The model fits well the overall time-lags spectrum in these sources (for a large parameter space). For NGC 4593 only, we detect a significant excess of delays in the U-band. The contribution of the diffuse BLR emission in the time-lags spectrum of this source is significant. It is possible to reduce the large best-fitting parameter space by combining the results with additional information, such as the observed Eddington ratio and average X-ray luminosity. We also provide an update to the analytic expression provided by Kammoun et al., for an X-ray source that is not powered by the accretion process, which can be used for any value of colour correction, and for two values of the black hole spin (0 and 0.998).Comment: Accepted for publication in MNRA

Performance Studies of Prototype II for the CASTOR forward Calorimeter at the CMS Experiment

We present results of the performance of the second prototype of the CASTOR quartz-tungsten sampling calorimeter, to be installed in the very forward region of the CMS experiment at the LHC. The energy linearity and resolution, as well as the spatial resolution of the prototype to electromagnetic and hadronic showers are studied with E=20-200 GeV electrons, E=20-350 GeV pions, and E=50,150 GeV muons from beam tests carried out at CERN/SPS in 2004. The responses of the calorimeter using two different types of photodetectors (avalanche photodiodes APDs, and photomultiplier tubes PMTs) are compared.Comment: 16 pages, 22 figs., submitted to EPJ-