On the signature of z∼0.6z\sim 0.6 superclusters and voids in the Integrated Sachs-Wolfe effect

Through a large ensemble of Gaussian realisations and a suite of large-volume N-body simulations, we show that in a standard LCDM scenario, supervoids and superclusters in the redshift range $z\in[0.4,0.7]$ should leave a {\em small} signature on the ISW effect of the order $\sim 2 \mu$K. We perform aperture photometry on WMAP data, centred on such superstructures identified from SDSS LRGs, and find amplitudes at the level of 8 -- 11$\mu$K -- thus confirming the earlier work of Granett et al 2008. If we focus on apertures of the size \sim3.6\degr, then our realisations indicate that LCDM is discrepant at the level of $\sim4 \sigma$. If we combine all aperture scales considered, ranging from 1\degr--20\degr, then the discrepancy becomes $\sim2\sigma$, and it further lowers to $\sim 0.6 \sigma$ if only 30 superstructures are considered in the analysis (being compatible with no ISW signatures at $1.3\sigma$ in this case). Full-sky ISW maps generated from our N-body simulations show that this discrepancy cannot be alleviated by appealing to Rees-Sciama mechanisms, since their impact on the scales probed by our filters is negligible. We perform a series of tests on the WMAP data for systematics. We check for foreground contaminants and show that the signal does not display the correct dependence on the aperture size expected for a residual foreground tracing the density field. The signal also proves robust against rotation tests of the CMB maps, and seems to be spatially associated to the angular positions of the supervoids and superclusters. We explore whether the signal can be explained by the presence of primordial non-Gaussianities of the local type. We show that for models with \FNL=\pm100, whilst there is a change in the pattern of temperature anisotropies, all amplitude shifts are well below $<1\mu$K.Comment: 14 pages, 9 figures, matches accepted version in MNRA

A linear filter to reconstruct the ISW effect from CMB and LSS observations

The extraction of a signal from some observational data sets that contain different contaminant emissions, often at a greater level than the signal itself, is a common problem in Astrophysics and Cosmology. The signal can be recovered, for instance, using a simple Wiener filter. However, in certain cases, additional information may also be available, such as a second observation which correlates to a certain level with the sought signal. In order to improve the quality of the reconstruction, it would be useful to include as well this additional information. Under these circumstances, we have constructed a linear filter, the linear covariance-based filter, that extracts the signal from the data but takes also into account the correlation with the second observation. To illustrate the performance of the method, we present a simple application to reconstruct the so-called Integrated Sachs-Wolfe effect from simulated observations of the Cosmic Microwave Background and of catalogues of galaxies.Comment: 8 pages, 6 figures, accepted for publication in the IEEE Journal of Selected Topics in Signal Processin

The origin of the LMC stellar bar: clues from the SFH of the bar and inner disk

We discuss the origin of the LMC stellar bar by comparing the star formation histories (SFH) obtained from deep color-magnitude diagrams (CMDs) in the bar and in a number of fields in different directions within the inner disk. The CMDs, reaching the oldest main sequence turnoffs in these very crowded fields, have been obtained with VIMOS on the VLT in service mode, under very good seeing conditions. We show that the SFHs of all fields share the same patterns, with consistent variations of the star formation rate as a function of time in all of them. We therefore conclude that no specific event of star formation can be identified with the formation of the LMC bar, which instead likely formed from a redistribution of disk material that occurred when the LMC disk became bar unstable, and shared a common SFH with the inner disk thereafter. The strong similarity between the SFH of the center and edge of the bar rules out significant spatial variations of the SFH across the bar, which are predicted by scenarios of classic bar formation through buckling mechanisms.Comment: MNRAS Letters, accepte

Characteristics of Disadvantaged Students. A Selection of Student Participants

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Impact of Scale Dependent Bias and Nonlinear Structure Growth on the ISW Effect: Angular Power Spectra

We investigate the impact of nonlinear evolution of the gravitational potentials in the LCDM model on the Integrated Sachs-Wolfe (ISW) contribution to the CMB temperature power spectrum, and on the cross-power spectrum of the CMB and a set of biased tracers of the mass. We use an ensemble of N-body simulations to directly follow the potentials and compare results to perturbation theory (PT). The predictions from PT match the results to high precision for k<0.2 h/Mpc. We compute the nonlinear corrections to the angular power spectrum and find them to be <10% of linear theory for l<100. These corrections are swamped by cosmic variance. On scales l>100 the departures are more significant, however the CMB signal is more than a factor 10^3 larger at this scale. Nonlinear ISW effects therefore play no role in shaping the CMB power spectrum for l<1500. We analyze the CMB--density tracer cross-spectrum using simulations and renormalized bias PT, and find good agreement. The usual assumption is that nonlinear evolution enhances the growth of structure and counteracts linear ISW on small scales, leading to a change in sign of the CMB-LSS cross-spectrum at small scales. However, PT analysis suggests that this trend reverses at late times when the logarithmic growth rate f(a)=dlnD/dlna<0.5 or om_m(a)<0.3. Numerical results confirm these expectations and we find no sign change in ISW-LSS cross-power for low redshifts. Corrections due to nonlinearity and scale dependence of the bias are found to be <10% for l<100, therefore below the S/N of the current and future measurements. Finally, we estimate the CMB--halo cross-correlation coefficient and show that it can be made to match that for CMB--dark matter to within 5% for thin redshift shells, mitigating the need to model bias evolution.Comment: 27 pages, 19 figure. Hi-res. version: http://www.itp.uzh.ch/~res/NonlinearISW.HiRes.pd

Development, Characterization, and In Vitro Evaluation of Tamoxifen Microemulsions

Microemulsions (MEs) were designed by an innovative rational development, characterized, and used to load up to 20 mM of Tamoxifen citrate (TMX). They were made with acceptable and well-characterized excipients for all the routes of administration. Some of their properties, such as nanometric mean size and long stability shelf life, make them interesting drug delivery systems. The results obtained after the in vitro inhibition of estradiol-induced proliferation in MCF-7 breast cancer cells demonstrated a significant effect in cell growth. A decreasing of at least 90% in viable cells was shown after the incubation with MEs containing 20 mM of TMX. Besides, two compositions which loaded 10 mM of drug showed a cytotoxic effect higher than 70%. These results encourage the evaluation of alternative protocols for this drug administration, not only for estrogen receptor (ER) positive tumors, but also for ER negative