Review of Ian Levy, Philip Krey, and Thomas Ryan, \u3ci\u3eThe Bible in Medieval Tradition: The Letter to the Romans.\u3c/i\u3e

Paul’s Letter to the Romans is the fullest account of Paul’s overall theology, and hence is the primary document for understanding the earliest Christian thought. Commentaries on the Letter to the Romans generally provide theologians the perfect venue with which to depict their understanding of the basic elements of Christianity, and it would follow that students and proponents of medieval scripture exegesis and theology should have ready access to Romans commentaries in translation. Thomas Aquinas’s commentary has recently become more widely available, and a translation of William of St. Thierry was published by Cistercian Publications in 1980, but until this volume, relatively little else has been available in English. The late H. Lawrence Bond, one of the founders of this series, decided that the time was ripe to provide a collection of the medieval commentators who were the most influential in the development of the theology of the age, and began this task but did not live to complete it. His coeditors worked to bring his translations into their final form and provided translations of other works; this volume serves as a worthy memorial to Larry’s scholarship and spirit

Matĕj of Janov: \u3ci\u3eCorpus Mysticum, Communionem,\u3c/i\u3e and the Lost Treatise of His \u3ci\u3eRegulae\u3c/i\u3e

The Bohemian theologian Matěj of Janov (d.1393) is little known outside of Czech Hussite scholarship, yet his Regulae Veteris et Novi Testamentum is arguably as important an influence on the genesis and development of Hussitism, as is the thought of John Wyclif. The chief Hussite theologian Jakoubek of Střibro relied on his works, and his emphasis on the need for daily Eucharist for all Christians seems to have been central to the utraquist ideal central to Hussitism. This article describes the structure and content of Matěj’s Regulae, a carefully constructed sustained argument of the threat of Antichrist facing the church, and the nature of the reforms needed to respond to them. The editions of Kybal (1908–1926) and Nechutová (1993) present the extant books of the Regulae, but Book Two treatise 2 appears to have been lost. Based on my argument for the overall structure of the Regulae, I attempt to reconstruct the contents of this book, which I will argue is directly related to Matěj’s very high regard for his predecessor, the preacher Jan Milič of Kromeřiž

Histopathologic and Biochemical Responses in Arctic Marine Bivalve Molluscs Exposed to Experimentally Spilled Oil

Following two experimental spills of chemically dispersed and undispersed crude oil in shallow bays on the northwest coast of Baffin Island, Canadian Arctic, the bivalve molluscs Mya truncata and Macoma calcarea accumulated significant amounts of petroleum hydrocarbons in bays receiving dispersed oil and in those receiving crude oil alone (Boehm et all., 1987). Following the spills, Mya released accumulated hydrocarbons more rapidly than Macoma. ... The results of the biochemical analyses indicate that Mya from the four bays were not severely stressed by either dispersed oil or oil alone. Immediately after the spill, clams from the dispersal oil bays were nearly normal, while those from the bay receiving oil alone appeared stressed. These results seem to corroborate results from analytical chemistry and histopathology: that the acute effects of dispersed oil are greater than those of undispersed oil, but effects of undispersed oil on infaunal molluscs develop more slowly and persist longer than those from dispersed oil.Key words: oil spill, dispersant, Mya truncata, Macoma calcarea, histopathology, biochemistry, neoplasia, free amino acids, glycogen, parasitesMots clés: marée noire, agent de dispersion, Mya truncata, Macoma calcarea, histopathologie, biochimie, néoplasme, acides aminés libres, glycogène, parasite

High level software for 4.8 GHz LHC Schottky system

The performance of the LHC depends critically on the accurate measurements of the betatron tunes. The betatron tune values of each LHC beam may be measured without excitation using a newly installed transverse Schottky monitor. A high-level software package written in Java has been developed for the Schottky system. The software allows end users to monitor and control the Schottky system, and provides them with non-destructive and continuous bunch-by-bunch measurements for the tunes, momentum spreads, chromaticities and emittances of the LHC beams. It has been tested with both proton and lead ion beams at the LHC with very successful results.Comment: 3 pp. Particle Accelerator, 24th Conference (PAC'11) 2011. 28 Mar - 1 Apr 2011. New York, US

Two females with mutations in USP9X highlight the variable expressivity of the intellectual disability syndrome

The genetic causes of intellectual disability (ID) are heterogeneous and include both chromosomal and monogenic etiologies. The X-chromosome is known to contain many ID-related genes and males show a marked predominance for intellectual disability. Here we report two females with syndromic intellectual disability. The first individual was relatively mild in her presentation with mild-moderate intellectual disability, hydronephrosis and altered pigmentation along the lines of Blaschko without additional congenital anomalies. A second female presented shortly after birth with dysmorphic facial features, post-axial polydactyly and, on follow-up assessment, demonstrated moderate intellectual disability. Chromosomal studies for Individual 1 identified an X-chromosome deletion due to a de novo pericentric inversion; the inversion breakpoint was associated with deletion of the 5′UTR of the USP9X, a gene which has been implicated in a syndromic intellectual disability affecting females. The second individual had a de novo frameshift mutation detected by whole-exome sequencing that was predicted to be deleterious, NM_001039590.2 (USP9X): c.4104_4105del (p.(Arg1368Serfs*2)). Haploinsufficiency of USP9X in females has been associated with ID and congenital malformations that include heart defects, scoliosis, dental abnormalities, anal atresia, polydactyly, Dandy Walker malformation and hypoplastic corpus callosum. The extent of the congenital malformations observed in Individual 1 was less striking than Individual 2 and other individuals previously reported in the literature, and suggests that USP9X mutations in females can have a wider spectrum of presentation than previously appreciated

Evidence and theory for lower rates of depression in larger US urban areas

It is commonly assumed that cities are detrimental to mental health. However, the evidence remains inconsistent and at most, makes the case for differences between rural and urban environments as a whole. Here, we propose a model of depression driven by an individual’s accumulated experience mediated by social networks. The connection between observed systematic variations in socioeconomic networks and built environments with city size provides a link between urbanization and mental health. Surprisingly, this model predicts lower depression rates in larger cities. We confirm this prediction for US cities using four independent datasets. These results are consistent with other behaviors associated with denser socioeconomic networks and suggest that larger cities provide a buffer against depression. This approach introduces a systematic framework for conceptualizing and modeling mental health in complex physical and social networks, producing testable predictions for environmental and social determinants of mental health also applicable to other psychopathologies

The psychopathology p factor: will it revolutionise the science and practice of child and adolescent psychiatry?

The psychopathology p factor has emerged from a series of strong empirical studies, largely in the adult psychiatry literature. Here, some of the recent findings relating to the p factor in children and adolescents are considered and the implications for child and adolescent psychiatry are discussed. Is it essential to covary for ‘p’ when we study specific domains of psychopathology? Do neurodevelopmental conditions make up part of the psychopathology p factor? How do we treat the ‘p factor’ in clinics? This editorial considers some of the contributions from this issue of Journal of Child Psychology and Psychiatry together with the wider literature that speak to these issues

Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences.

The dearth of age-appropriate formulations of many medicines for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide. We provide information on current administration practices of pediatric medicines and describe key stakeholder preferences for new formulation characteristics. We surveyed children aged 6-12 years, parents/caregivers over age 18 with children under age 12, and healthcare workers in 10 regions of Tanzania to determine current pediatric medicine prescription and administration practices as well as preferences for new formulations. Analyses were stratified by setting, pediatric age group, parent/caregiver education, and healthcare worker cadre. Complete data were available for 206 children, 202 parents/caregivers, and 202 healthcare workers. Swallowing oral solid dosage forms whole or crushing/dissolving them and mixing with water were the two most frequently reported methods of administration. Children frequently reported disliking medication taste, and many had vomited doses. Healthcare workers reported medicine availability most significantly influences prescribing practices. Most parents/caregivers and children prefer sweet-tasting medicine. Parents/caregivers and healthcare workers prefer oral liquid dosage forms for young children, and had similar thresholds for the maximum number of oral solid dosage forms children at different ages can take. There are many impediments to acceptable and accurate administration of medicines to children. Current practices are associated with poor tolerability and the potential for under- or over-dosing. Children, parents/caregivers, and healthcare workers in Tanzania have clear preferences for tastes and formulations, which should inform the development, manufacturing, and marketing of pediatric medications for resource-limited settings