45 research outputs found

    'Asexual isn't who I am': the politics of asexuality

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    Some literature on asexuality has claimed that it is inherently radical and contains the potential for resistance. Unfortunately, this literature has tended to be unempirical, has imagined asexuality as a disembodied entity, and has marginalised the multiple identities held by asexual people. This article, inspired by Plummer’s critical humanist approach, seeks to explore how individuals understand their asexuality to encourage forms of political action in the areas of identity, activism, online spaces, and LGBT politics. What we found was a plurality of experiences and attitudes with most adopting a pragmatic position in response to their social situation which saw large-scale political action as irrelevant. We conclude by reflecting on what these results mean for those who see asexuality as potentially radical

    Hybrid copula mixed models for combining case-control and cohort studies in meta-analysis of diagnostic tests

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    Copula mixed models for trivariate (or bivariate) meta-analysis of diagnostic test accuracy studies accounting (or not) for disease prevalence have been proposed in the biostatistics literature to synthesize information. However, many systematic reviews often include case-control and cohort studies, so one can either focus on the bivariate meta-analysis of the case-control studies or the trivariate meta-analysis of the cohort studies, as only the latter contains information on disease prevalence. In order to remedy this situation of wasting data we propose a hybrid copula mixed model via a combination of the bivariate and trivariate copula mixed model for the data from the case-control studies and cohort studies, respectively. Hence, this hybrid model can account for study design and also due to its generality can deal with dependence in the joint tails. We apply the proposed hybrid copula mixed model to a review of the performance of contemporary diagnostic imaging modalities for detecting metastases in patients with melanoma

    Factor copula models for item response data

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    Factor or conditional independence models based on copulas are proposed for multivariate discrete data such as item responses. The factor copula models have interpretations of latent maxima/minima (in comparison with latent means) and can lead to more probability in the joint upper or lower tail compared with factor models based on the discretized multivariate normal distribution (or multidimensional normal ogive model). Details on maximum likelihood estimation of parameters for the factor copula model are given, as well as analysis of the behavior of the log-likelihood. Our general methodology is illustrated with several item response data sets, and it is shown that there is a substantial improvement on existing models both conceptually and in fit to data

    A vine copula mixed effect model for trivariate meta-analysis of diagnostic test accuracy studies accounting for disease prevalence

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    A bivariate copula mixed model has been recently proposed to synthesize diagnostic test accuracy studies and it has been shown that it is superior to the standard generalized linear mixed model in this context. Here, we call trivariate vine copulas to extend the bivariate meta-analysis of diagnostic test accuracy studies by accounting for disease prevalence. Our vine copula mixed model includes the trivariate generalized linear mixed model as a special case and can also operate on the original scale of sensitivity, specificity, and disease prevalence. Our general methodology is illustrated by re-analyzing the data of two published meta-analyses. Our study suggests that there can be an improvement on trivariate generalized linear mixed model in fit to data and makes the argument for moving to vine copula random effects models especially because of their richness, including reflection asymmetric tail dependence, and computational feasibility despite their three dimensionality

    A copula-based sensitivity analysis method and its application to a North Sea sediment transport model

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    This paper describes a novel sensitivity analysis method, able to handle dependency relationships between model parameters. The starting point is the popular Morris (1991) algorithm, which was initially devised under the assumption of parameter independence. This important limitation is tackled by allowing the user to incorporate dependency information through a copula. The set of model runs obtained using latin hypercube sampling, are then used for deriving appropriate sensitivity measures. Delft3D-WAQ (Deltares, 2010) is a sediment transport model with strong correlations between input parameters. Despite this, the parameter ranking obtained with the newly proposed method is in accordance with the knowledge obtained from expert judgment. However, under the same conditions, the classic Morris method elicits its results from model runs which break the assumptions of the underlying physical processes. This leads to the conclusion that the proposed extension is superior to the classic Morris algorithm and can accommodate a wide range of use cases.Petroleum EngineeringApplied Probabilit

    Development of a Causal Model for Air Transport Safety

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    The development of the Dutch international airport Schiphol has been the subject of fierce political debate for several decades. One of the considerations has been the safety of the population living around the airport. In the debate about the acceptability of the risks associated with the air traffic above The Netherlands the need has arisen to gain a more thorough understanding of the accident genesis in air traffic, with the ultimate aim of improving the safety situation in air traffic in general and around Schiphol in particular. To this end a research effort has been started in order to develop causal models for air traffic risks in the expectation that these will ultimately give the necessary insights. The first step is to organise the information available in accident databases.Copyright © 2005 by ASM
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