140 research outputs found
Community action: value or instrument? An ethics and planning critical review
The community concept has maintained a constant and growing interest in urban studies and many related fields. The
origin of this continuing interest seems to derive from the importance of the concept of community within diverse forms of political
language and interpretations within different planning practices. In this contribution, through the analysis of different ethical and
planning theories, we want to provide an update framework on community action. According to this objective, the argumentation
will proceed through a literature review on four ethics theories and three key aspects related to spatial planning, as well as matching this theoretical analysis with exemplifying practices. The final objective is to provide an original analysis on drivers and outcomesof different forms of community, raising general issues that refer to spatial planning, social organization and regulation
Gated communities: Definitions, causes and consequences
Gated communities became an 'object of study' in the 1990s as social scientists observed their growth in several cities; they are now a feature of the urban landscape in most cities around the world. The expansion of gated communities has led to prolific research, examining different aspects of this type of residential development and providing evidence from case studies worldwide. This paper reviews how gated communities are conceptualised according to the literature and identifies the main factors influencing their development. It also considers spatial, economic, political and social consequences of the development of gated communities. These elements should be taken into account by planners and policymakers to minimise their negative impacts and maximise the positive consequences of a residential option that is likely to be part of the urban landscape for a long time
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The anti-epileptic drug Valproic Acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro
Valproic acid (VPA) is used widely to treat epilepsy and bipolar disorder. Women undergoing VPA treatment reportedly have an increased incidence of polycystic ovarian syndrome (PCOS)-like symptoms including hyperandrogenism and oligo- or amenorrhoea. To investigate potential direct effects of VPA on ovarian steroidogenesis we used primary bovine theca (TC) and granulosa (GC) cells maintained under conditions that preserve their 'follicular' phenotype. Effects of VPA (7.8-500 µg/ml) on TC were tested with/without LH. Effects of VPA on GC were tested with/without FSH or IGF analogue. VPA reduced (P99% decrease; P<0.0001) with lesser effects on LHR, STAR, CYP11A1 and HSD3B1 mRNA (<90% decrease; P<0.05). VPA only reduced TC progesterone secretion induced by the highest (luteinizing) LH dose tested; TC number was unaffected by VPA. At higher concentrations (125-500 µg/ml) VPA inhibited basal, FSH- and IGF-stimulated estradiol secretion (P<0.0001) by GC without affecting progesterone secretion or cell number. VPA reversed FSH-induced upregulation of CYP19A1 and HSD17B1 mRNA abundance (P<0.001). The potent histone deacetylase (HDAC) inhibitors trichostatin A and scriptaid also suppressed TC androstenedione secretion and granulosal cell oestrogen secretion suggesting that the action of VPA reflects its HDAC inhibitory properties. In conclusion, these findings refute the hypothesis that VPA has a direct stimulatory action on TC androgen output. On the contrary, VPA inhibits both LH-dependent androgen production and FSH/IGF-dependent estradiol production in this in vitro bovine model, likely by inhibition of HDAC
On the Power and Weakness of Rational Expectations: Logical Fallacies, Periodic Bubbles and Business Cycles
Interictal electroencephalographic findings in children and adults with temporal lobe tumors
Uncovering the Costs of the Iraq War
Fred Foldvary reviews the recent book by Joseph Stiglitz and Linda Bilmes, The Three Trillion Dollar War: The True Cost of the Iraq Conflict. Foldvary commends the book for its assembly of both the budgeted and implicit costs of the war, and its analysis of the economic impact of the war. The review posits that the better knowledge and accounting of the war costs as provided by this work will aid in establishing a more coherent dialog on policy for dealing with this and future conflicts abroad.war,Iraq,federal deficit,governmental accounting,governmental expenditures
Marginalists Who Confronted Land
Although the neoclassical turn in economics demoted land as a factor, important economists of neoclassical thinking, from neoclassical predecessors such Hermann-Heinrich Gossen through figures such as Leon Walras, did view land as a distinct factor of production. Walras, in particular, favored the use of land rent for public revenue. This paper examines the treatment of land by several neoclassical and Austrian economists and shows how, although the neoclassical school today has managed to bury land, some of the key figures who founded these schools did confront land as a factor. The burial of land is thus not inherent in neoclassical economics, but is a historical development that can be reversed. Copyright 2008 American Journal of Economics and Sociology, Inc..
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