774 research outputs found
Making sense of business analytics : the case of two start-ups
Business analytics have enabled businesses to leverage unstructured and dispersed data in order to improve their operations and position themselves better within a highly turbulent environment. While much discussion has been focused on how businesses can move from data to insights to decision making, much less is known around how businesses actually interpret the insights provided by business analytics tools. This extended abstract proposes the use of sense-making as the theoretical lens for interpreting these insights, combined with contextual information. We will be using two case studies to further explore the applicability of our proposition
The Wireless Readiness Innovation Index: Enhancing the Effectiveness of the Public Sector in New Service Introduction
National and regional public authorities need to align their planned introduction of mobile/wireless innovation with the maturity levels of both their workforce (who will manage and maintain the new applications) and their citizens (who will use them). We draw on the experience of working with local authorities in three Mediterranean countries (Greece, Italy and Spain) to develop a method towards the effective introduction and adoption of innovative mobile services by public organizations. Specifically, we discuss the development and pilot implementation of a) the Wireless Readiness Innovation Index , a tool that aims at measuring the local authority’s and end users’ readiness towards providing and using innovative wireless services and b) the Wireless Innovation Operational Toolkit , a tool that aims at matching users’ and local authority’s readiness levels with candidate services so as to maximize the likelihood of successful introduction and sustained use
EXPLORING THE ADOPTION OF UBIQUITOUS INFORMATION SYSTEMS WITHIN THE MUSEUM CONTEXT
Wireless and mobile technologies are gradually enabling the provision of innovative information services within almost all environments. This study explores the adoption of ubiquitous museum information systems that can significantly enhance and enrich the museum visit. We draw on traditional IS adoption theories and theories from Museum Studies to develop our theoretical model which is empirically tested through a survey addressed to museum visitors (n=118). Model hypotheses are tested through Partial Least Squares modelling. The results show that Performance Expectancy and Personal Innovativeness still represent the core predictors toward the adoption of museum information systems. However, we also report on the predictive strength of two context-related factors, Invisibility and Interaction, which appear to play a particular role toward the formulation of favourable user perceptions. The paper concludes with implications on the design of museum information systems and specific suggestions for future research
Developing e-services for Lagos State: Understanding the impact of cultural perceptions and working practices
The development of e-services is not only a technological phenomenon, but involves organizational and social complexities. In this paper, we build upon an interpretive case study, and examine Lagos State’s initiative, in order to showcase how the implementation of public sector e-services have been affected by organizational and cultural perceptions and the working practices of individuals in a developing country. This research provides insights for international organizations that determine the status of countries by providing online access, products and services to their citizens, and to Internet Service Providers who pursue new territories for the provision of new products and services. It also informs governments around the globe about cultural perceptions and working practices, thereby helping them determine their developmental progress and decide their future endeavors
Finite temperature calculations for the bulk properties of strange star using a many-body approach
We have considered a hot strange star matter, just after the collapse of a
supernova, as a composition of strange, up and down quarks to calculate the
bulk properties of this system at finite temperature with the density dependent
bag constant. To parameterize the density dependent bag constant, we use our
results for the lowest order constrained variational (LOCV) calculations of
asymmetric nuclear matter. Our calculations for the structure properties of the
strange star at different temperatures indicate that its maximum mass decreases
by increasing the temperature. We have also compared our results with those of
a fixed value of the bag constant. It can be seen that the density dependent
bag constant leads to higher values of the maximum mass and radius for the
strange star.Comment: 21 pages, 2 tables, 12 figures Astrophys. (2011) accepte
Fear of the unknown: a pre-departure qualitative study of Turkish international students
This paper presents findings from eleven in-depth interviews with Turkish undergraduate students, who were, by the time of data collection, about to spend a semester at a European university under the Erasmus exchange scheme. The students all agreed to be interviewed about their feelings about studying in a foreign culture, and were found to be anxious prior to departure about the quality of accommodation in the new destination, their language ability and the opportunity to form friendships. Fears were expressed about possible misconceptions over Turkey as a Muslim and a developing country. Suggestions are made for HEI interventions to allay student travellers’ concerns
Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21. The core/shell structure was sprayed onto the surface of 316L stainless steel stents using a coaxial electrospray process with the aim of creating a coating that exhibited a differential release of the two drugs. The prepared stents displayed a uniform coating consisting of nano/micro particles. In vitro drug release experiments were performed, and we demonstrated that a biphasic mathematical model was capable of capturing the data, indicating that the release of the two drugs conformed to a diffusion-controlled release system. We demonstrated that our coating was capable of inhibiting the adhesion and activation of platelets, as well as the proliferation and migration of smooth muscle cells (SMCs), indicating its good biocompatibility and anti-proliferation qualities. In an in vivo porcine coronary artery model, the SZ-21/DTX drug-loaded hydrophobic core/hydrophilic shell particle coating stents were observed to promote re-endothelialization and inhibit neointimal hyperplasia. This core/shell particle-coated stent may serve as part of a new strategy for the differential release of different functional drugs to sequentially target thrombosis and in-stent restenosis during the vascular repair process and ensure rapid re-endothelialization in the field of cardiovascular disease
Physical Aspects of Pseudo-Hermitian and -Symmetric Quantum Mechanics
For a non-Hermitian Hamiltonian H possessing a real spectrum, we introduce a
canonical orthonormal basis in which a previously introduced unitary mapping of
H to a Hermitian Hamiltonian h takes a simple form. We use this basis to
construct the observables O of the quantum mechanics based on H. In particular,
we introduce pseudo-Hermitian position and momentum operators and a
pseudo-Hermitian quantization scheme that relates the latter to the ordinary
classical position and momentum observables. These allow us to address the
problem of determining the conserved probability density and the underlying
classical system for pseudo-Hermitian and in particular PT-symmetric quantum
systems. As a concrete example we construct the Hermitian Hamiltonian h, the
physical observables O, the localized states, and the conserved probability
density for the non-Hermitian PT-symmetric square well. We achieve this by
employing an appropriate perturbation scheme. For this system, we conduct a
comprehensive study of both the kinematical and dynamical effects of the
non-Hermiticity of the Hamiltonian on various physical quantities. In
particular, we show that these effects are quantum mechanical in nature and
diminish in the classical limit. Our results provide an objective assessment of
the physical aspects of PT-symmetric quantum mechanics and clarify its
relationship with both the conventional quantum mechanics and the classical
mechanics.Comment: 45 pages, 13 figures, 2 table
Preimplantation genetic testing for Neurofibromatosis type 1:more than 20 years of clinical experience
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that affects the skin and the nervous system. The condition is completely penetrant with extreme clinical variability, resulting in unpredictable manifestations in affected offspring, complicating reproductive decision-making. One of the reproductive options to prevent the birth of affected offspring is preimplantation genetic testing (PGT). We performed a retrospective review of the medical files of all couples (n = 140) referred to the Dutch PGT expert center with the indication NF1 between January 1997 and January 2020. Of the couples considering PGT, 43 opted out and 15 were not eligible because of failure to identify the underlying genetic defect or unmet criteria for in vitro fertilization (IVF) treatment. The remaining 82 couples proceeded with PGT. Fertility assessment prior to IVF treatment showed a higher percentage of male infertility in males affected with NF1 compared to the partners of affected females. Cardiac evaluations in women with NF1 showed no contraindications for IVF treatment or pregnancy. For 67 couples, 143 PGT cycles were performed. Complications of IVF treatment were not more prevalent in affected females compared to partners of affected males. The transfer of 174 (out of 295) unaffected embryos led to 42 ongoing pregnancies with a pregnancy rate of 24.1% per embryo transfer. There are no documented cases of misdiagnosis following PGT in this cohort. With these results, we aim to provide an overview of PGT for NF1 with regard to success rate and safety, to optimize reproductive counseling and PGT treatment for NF1 patients.</p
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