General practitioners' views of pharmacists' current and potential contributions to medication review and prescribing in New Zealand

INTRODUCTION: Internationally, non-medical practitioners are increasingly involved in tasks traditionally undertaken by general practitioners (GPs), such as medication review and prescribing. This study aims to evaluate GPs' perceptions of pharmacists' contributions to those services. METHODS: Semi-structured interviews were carried out in two localities with GPs whose patients had and had not undergone a pharmacist-led adherence support Medication Use Review (MUR). GPs were asked their opinions of pharmacists' provision of MUR, clinical medication review and prescribing. Data were analysed thematically using NVivo 8 and grouped by strengths, weaknesses, opportunities and threats (SWOT) category. FINDINGS: Eighteen GPs were interviewed. GPs mentioned their own skills, training and knowledge of clinical conditions. These were considered GPs' major strengths. GPs' perceived weaknesses were their time constraints and heavy workloads. GPs thought pharmacists' strengths were their knowledge of pharmacology and having more time for in-depth medication review than GPs. Nevertheless, GPs felt pharmacist-led medication reviews might confuse patients, and increase GP workloads. GPs were concerned that pharmacist prescribing might include pharmacists making a diagnosis. This is not the proposed model for New Zealand. In general, GPs were more accepting of pharmacists providing medication reviews than of pharmacist prescribing, unless appropriate controls, close collaboration and co-location of services took place. CONCLUSION: GPs perceived their own skills were well suited to reviewing medication and prescribing, but thought pharmacists might also have strengths and skills in these areas. In future, GPs thought that working together with pharmacists in these services might be possible in a collaborative setting

An Approach to Building Musical Bioprocessors with Physarum polycephalum Memristors

This chapter presents an account of our investigation into developing musical processing devices using biological components. Such work combines two vibrant areas of unconventional computing research: Physarum polycephalum and the memristor. P. polycephalum is a plasmodial slime mould that has been discovered to display behaviours that are consistent with that of the memristor: a hybrid memory and processing component. Within the chapter, we introduce the research’s background and our motives for undertaking the study. Then, we demonstrate P. polycephalum’s memristive abilities and present our approach to enabling its integration into analogue circuitry. Following on, we discuss different techniques for using P. polycephalum memristors to generate musical responses

A Nonlinear Approach to Generate Creative Data using Physarum polycephalum-based Memristors

This chapter presents a generic biocomputing system developed to generate data for creative pieces such as music and art. It harnesses the nonlinear behaviour of Physarum polycephalum-based memristors, which is in contrast to stochastic processes that are often explored in creative systems. Within this chapter, we explain the advantages of using biomemristors for such applications and discuss a compact and portable biocomputer called PhyBox. It harnesses biomemristors as processing units and highlights the need for non-digital ways of representing, processing, and storing data. The system generates new creative pieces that are inspired by seed data that is input by the user. It allows the user to determine the degree of similarity between the output and the pre-existing creative data by controlling the nonlinearity of Physarum polycephalum-based memristors. The mapping procedure considers the resistor's behaviour to be ideal and reproduces the pre-existing data if a resistor is connected instead of a memristor. Our system is generic because it does not depend on the type of creative piece that is being processed. The chapter presents results from testing the system under dif erent scenarios and provides ways for creative practitioners to adopt Unconventional Computing technologies in their works

Designing Brain-computer Interfaces for Sonic Expression

Brain-computer interfaces (BCIs) are beneficial for patients who are suffering from motor disabilities because it offers them a way of creative expression, which improves mental well-being. BCIs aim to establish a direct communication medium between the brain and the computer. Therefore, unlike conventional musical interfaces, it does not require muscular power. This paper explores the potential of building sound synthesisers with BCIs that are based on steady-state visually evoked potential (SSVEP). It investigates novel ways to enable patients with motor disabilities to express themselves. It presents a new concept called sonic expression, that is to express oneself purely by the synthesis of sound. It introduces new layouts and designs for BCI-based sound synthesisers and the limitations of these interfaces are discussed. An evaluation of different sound synthesis techniques is conducted to find an appropriate one for such systems. Synthesis techniques are evaluated and compared based on a framework governed by sonic expression

On Unconventional Computing for Sound and Music

Advances in technology have had a significant impact on the way in which we produce and consume music. The music industry is most likely to continue progressing in tandem with the evolution of electronics and computing technology. Despite the incredible power of today’s computers, it is commonly acknowledged that computing technology is bound to progress beyond today’s conventional models. Researchers working in the relatively new field of Unconventional Computing (UC) are investigating a number of alternative approaches to develop new types of computers, such as harnessing biological media to implement new kinds of processors. This chapter introduces the field of UC for sound and music, focusing on the work developed at Plymouth University’s Interdisciplinary Centre for Computer Music Research (ICCMR) in the UK. From musical experiments with Cellular Automata modelling and in vitro neural networks, to quantum computing and bioprocessing, this chapter introduces the substantial body of scientific and artistic work developed at ICCMR. Such work has paved the way for ongoing research towards the development of robust general-purpose bioprocessing components, referred to as biomemristors, and interactive musical biocomputers

Validity and worth in the science curriculum: learning school science outside the laboratory

It is widely acknowledged that there are problems with school science in many developed countries of the world. Such problems manifest themselves in a progressive decline in pupil enthusiasm for school science across the secondary age range and the fact that fewer students are choosing to study the physical sciences at higher levels and as careers. Responses to these developments have included proposals to reform the curriculum, pedagogy and the nature of pupil discussion in science lessons. We support such changes but argue from a consideration of the aims of science education that secondary school science is too rooted in the science laboratory; substantially greater use needs to be made of out-of-school sites for the teaching of science. Such usage should result in a school science education that is more valid and more motivating and is better at fulfilling defensible aims of school science education. Our contention is that laboratory-based school science teaching needs to be complemented by out-of-school science learning that draws on the actual world (e.g. through fieldtrips), the presented world (e.g. in science centres, botanic gardens, zoos and science museums) and the virtual worlds that are increasingly available through information and communications technologies (ICT)

Provision of long-term monitoring and late effects services following adult allogeneic haematopoietic stem cell transplant: a survey of UK NHS-based programmes

Despite international guidelines, optimal delivery models of late effects (LE) services for HSCT patients are unclear from the clinical, organizational and economic viewpoints. To scope current LE service delivery models within the UK NHS (National Health Service), in 2014, we surveyed the 27 adult allogeneic HSCT centres using a 30-question online tool, achieving a 100% response rate. Most LE services were led and delivered by senior physicians (>80% centres). Follow-up was usually provided in a dedicated allograft or LE clinic for the first year (>90% centres), but thereafter attrition meant that only ~50% of patients were followed after 5 years. Most centres (69%) had a standard operating procedure for long-term monitoring but access to a LE Multi-Disciplinary Team was rare (19% centres). Access to medical specialities necessary for LE management was good, but specialist interest in long-term HSCT complications was uncommon. Some screening (endocrinopathy, cardiovascular) was near universal, but other areas were more limited (mammography, cervical smears). Funding of extra staff and investigations were the most commonly perceived barriers to implementation of LE services. This survey shows variation in the long-term follow-up of allogeneic HSCT survivors within the UK NHS and further work is warranted to optimize effective, sustainable and affordable models of LE service delivery among this group