629 research outputs found

    Morphohistological Studies of Two Plant Species Used in Ethnomedicine

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    Morphohistological studies of two forest species of Annonaceae have been reported; the species covered are Xylopia aethiopica (Dunal) A. Rich and X. quintassii Engl. And Diels. Wood fibres range in length from 965 ± 4 µm in X. aethiopica to 853 ± 3 µm X. quintassii. Leaves are hypostomatic with paracytic stomata found only in the lower epidermis. The epidermal cell walls are straight. Epidermal crystals are cluster crystals, which are present in all the species. Communities bordering the Pre-Suhien Forest Reserve notably, Abrafo-Odumase, Mfuom and Ankaako use these plant species for the treatment of stomach and bronchial troubles as well as rheumatism

    Subacute Oral Toxicity Assessment of Alchornea cordifolia (Schumach and Thonn) Müll Arg (Euphorbiaceae) Extract in Rats

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    Purpose: To assess Alchornea cordifolia, a medicinal plant with numerous biological actions and uses in traditional medicine, for possible toxicity in rats.Methods: The probable effect of the ethanol extract of Alchornea cordifolia (250 - 2000 mg/kg, p.o.) by gavage was evaluated on blood cellular elements and chemistry, as well as on the weight and histology of vital organs of male adult Spraque-Dawley rats.Results: Daily administration of the extract for two weeks did not cause significant changes in most haematological indices and blood chemistry. However, a dose-dependent increase (p < 0.01) in neutrophils was observed. Relative organ weights were comparable in control and treated groups. Histopathological assessment of liver sections of treated-rats showed normal architecture at doses < 1000 mg/kg. However, in animals treated with 1000 and 2000 mg/kg, cloudy swelling of hepatocytes with vacuolar and hydropic degeneration were evident. Kidney architecture at all dose levels was normal.Conclusion: The results of the study show that administration of the ethanol extract of Alchornea cordifolia to male adult rats by gavage evoked histopathologic changes in the liver at doses > 1000 mg/kg. These findings call for caution in the use of Alchornea cordifolia especially in high doses.Keywords: Alchornea cordifolia, Rats, Subacute oral toxicity, Neutrophils, Hepatocytes, Hydropic denegeratio

    Biomass yield and fodder quality of Napier grass (Pennisetum purpureum) as affected by Pigeon pea (Cajanus cajan) intercrop and planting distance

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    The study sought to investigate the effect of two planting distances and Pigeon Pea (Cajanus cajan) intercrop on the biomass yield, chemical composition and in vitro organic matter digestibility (IVOMD) of Napier grass (Pennisetum purpureum). The treatments were laid in a 2x2 factorial RCBD. The factors were two planting distances (0.5x0.5 and 0.5x1m) and two levels of intercrop (Pigeon Pea intercrop and sole Napier grass). At 90-days, the grasses were harvested and biomass yield measured. The fodder was separated into leaves and stems for chemical and digestibility analysis in 2x2x2 factorial in CRD. The interaction at all levels was not significant for all the parameters. There was a significant main effect of planting distance, intercrop and botanical fraction on biomass yield, plant height, tiller number and fodder quality. Whilst biomass yield was higher (P=0.02) in the 0.5x0.5m, no significant difference was recorded in the effect of the intercrop. Whilst intercrop affected (P<0.05) IVOMD and ME, botanical fraction significantly affected DM, CP and ME. The leaf fraction had more (P<0.05) DM, CP and ME than the stem fraction. The study revealed that close planting distance enhanced biomass yield whilst Pigeon Pea intercrop and botanical fraction affected fodder quality of Napier grass

    Levels and Distribution of Heavy Metals in Weija Reservoir, Accra, Ghana

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    Reservoirs are normally subjected to various forms of degradation due to pollution arising from anthropogenic activities. Heavy metals are of particular concern because of their potential toxic effect and ability to bio-accumulate in aquatic ecosystems. Agricultural activities around the Weija reservoir and municipal waste leachate intrusion have been reported. Investigations were therefore conducted to determine the levels and distribution of heavy metals in the Weija reservoir. Specific heavy metals were determined in water, suspended particles, sediments and fish species using Flame Atomic Absorption Spectrophotometry. Mercury was analysed with a mercury analyser, which uses cold vapour. The result showed that the concentrations of metals were greater in sediment than the suspended particles and reservoir water; Cd, Cu, Ni, Pb and Zn were all below the chronic freshwater quality criteria for aquatic life. Iron (Fe) and Mn were the most abundant elements associated with the suspended solids, whiles Cd was the least. With the exception of Cu and Cd that were not detected in the fish species, the other metals were found at varying concentrations, but within acceptable thresholds. The concentrations of heavy metals in the various fish and prawn species were ranked in the following order: Parachanna obscura > Macrobrachium rosenbergii > Chrysicthys nigrodigitatus > Clarias batracus > Clarias gariepinus > Hemichromis faciatus > Sarotherodon melantheron. There were significant positive correlation between the following metals in water; Pb and Zn (r=0.66), Cr and As (r=0.52). Evidence from principal component analysis (PCA) suggested that two key source factors, characterised as related to mining and municipal solid wastes, underpinned heavy metal contamination in the Weija reservoir. Thus, illegal small-scale mining along the tributaries feeding the Weija reservoir affected the quality of water received in the reservoir

    Improved forage cultivation for increased in fodder availability and climate change mitigation in the Savanna agro-ecological zone of northern Ghana

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    The study was conducted to investigate the biomass yield and quality of two forage species Brachiaria ruziziensis (B. ruziziensis) and Sorghum almum (S. almum) in a Randomized Complete Block Design (RCBD) in two different locations (Bihinayili in the Savelugu District and Zanlerigu in the Nabdam District) in the Savanna agro-ecological zone of Ghana. Agronomic data were collected and representative samples of forage biomass taken at 60 days after planting to estimate dry matter yield and nutritive quality. The two-way interaction effect of forage species and experimental site was not significant for both agronomic and chemical parameters except for tiller number. The average leaf size was broader (P=0.006) in S. almum (299.0 cm2) than B. ruziziensis (85.0 cm2). Number of leaves per plant was higher (P=0.016) in B. ruziziensis (10.75). Number of tillers per plant in B. ruziziensis (9.62) was higher (P=0.001) than S. almum (2.88). Plant height was however, higher in S. almum (183.1 cm) than B. ruziziensis (90.1 cm). Dry matter yield of forages at 60 days after planting was higher (P<0.001) at Bihinayili (8.49 tons/ha) than that at Zanlerigu (2.23 tons/ha). The CP content of the forages at Bihinayili (89.7 g/kg DM) was also higher (P=0.018) than that at Zanlerigu (68.6 g/kg DM). Dry matter yield of B. ruziziensis (4.84 tons/ha) did not differ significantly from that of S. almum (5.88 tons/ha). In conclusion, B. ruziziensis and S. almum performed well within the Savanna agroecological zone and could enhance fodder supply and carbon sequestration

    Preliminary Investigation Into Some Aspects Of The Ecology Of Coastal Savannah Forest Soils In Ghana: A Case Study of the University of Cape Coast Nature Reserve

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    Stable Food Crops Turning Into Commercial Crops: Case studies of Teff, Wheat and Rice in Ethiopia The study was conducted in the University of Cape Coast Nature Reserve to investigate the levels of urease in the soils and to relate these levels to soil organic matter (SOM) content, soil moisture (SM) content, pH, temperature, particle size distribution and bulk density. The stratified random sampling method was employed to collect data within three 10 × 200 m belt transects. Soil samples were collected from 0 to 15 cm depth in different zones of the nature reserve between January and April, 2005. The mean soil urease levels ranged from 80.91 ± 4.72 to 132.36 ± 10.80 NH4+-N mg kg-1. Monthly variations in soil urease levels were highly significant (p < 0.01). The enzyme level varied significantly (p < 0.001) with topography. Multiple regression analysis showed that urease activity depended on SOM, SM, pH and soil temperature (p < 0.05). Soil texture and bulk density were similar in all the zones. SOM, SM, time and topography were the main factors which affected urease levels in the soils of the University of Cape Coast Nature Reserv

    Artificial Neural Network Model for Low Strength RC Beam Shear Capacity

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    This research was to investigate how the shear strength prediction of low strength reinforced concrete beams will improve under an ANN model. An existing database of 310 reinforced concrete beams without web reinforcement was divided into three sets of training, validation and testing. A total of 224 different architectural networks were tried, considering networks with one hidden layer as well as two hidden layers. Error measures of strength ratios were used to select the best ANN model which was then compared with 3 conventional design code equations in predicting the shear strength of 26 low strength RC beams. Even though the ANN was the most accurate, it was less conservative compared with the design code equations. A model reduction factor based on the characteristic strength concept is derived in this research and used to modify the ANN output. The modified ANN model is conservative in terms of safety and economy but not overly conservative as the conventional design equations. The procedure has been automated such that when new experimental sets are added to the database, the model can be updated and a new model could be developed

    A matching scheme for aquaculture; a graphing calculator approach

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    Graphing Calculator Technology possesses a lot of capabilities in solving a variety of scientific and non-scientific problems. Its programming abilities make it very flexible to use. Unfortunately, it has been underutilised. In this paper, we develop an application with the graphing calculator to handle the processes in a Matching Scheme for Assigning Fish Types to Ponds. The application gives an inclusion matrix which is used as the basis of the matching and finally gives summary of the assignment..Journal of Science and Technology (Ghana) Vol. 27 (2) 2007: pp. 99-10

    Trichilia monadelpha Bark Extracts Inhibit Carrageenan-Induced Foot-Oedema in the 7-Day Old Chick and the Oedema Associated with Adjuvant-Induced Arthritis in Rats

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    Trichilia monadelpha (Thonn) JJ De Wilde (Meliaceae) bark extract is used in African traditional medicine for the management of various disease conditions including inflammatory disorders such as arthritis. The present study was undertaken to evaluate the anti-inflammatory properties of aqueous (TWE), alcoholic (TAE) and petroleum ether extract (TPEE) of T. monadelpha using the 7-day old chick-carrageenan footpad oedema (acute inflammation) and the adjuvant-induced arthritis model in rats (chronic inflammation). TWE and TPEE significantly inhibited the chick-carrageenan footpad oedema with maximal inhibitions of 57.79&plusmn;3.92 and 63.83&plusmn;12 respectively, but TAE did not. The reference anti-inflammatory drugs (diclofenac and dexamethasone) inhibited the chick-carrageenan-induced footpad oedema, with maximal inhibitions of 64.92&plusmn;2.03 and 71.85&plusmn;15.34 respectively. Furthermore, all the extracts and the reference anti-inflammatory agents (diclofenac, dexamethasone, methotrexate) inhibited the inflammatory oedema associated with adjuvant arthritis with maximal inhibitions of 64.41&plusmn;5.56, 57.04&plusmn;8.57, 62.18&plusmn;2.56%, for TWE, TAE and TPEE respectively and 80.28&plusmn;5.79, 85.75&plusmn;2.96, 74.68&plusmn;3.03% for diclofenac, dexamethasone and methotrexate respectively. Phytochemical screening of the plant bark confirmed the presence of a large array of plant constituents such as alkaloids, glycosides, flavonoids, saponins, steroids, tannins and terpenoids, all of which may be potential sources of phyto-antiinflammatory agents. In conclusion, our work suggests that T. monadelpha is a potential source of antiinflammatory agents.Keywords: Antiinflammatory, Arthritis, Trichilia monadelpha, chick-carrageenan, phyto-antiinflammatory
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