The average magnetic field draping and consistent plasma properties of the Venus magnetotail

A new technique has been developed to determine the average structure of the Venus magnetotail (in the range from −8 Rv to −12 Rv) from the Pioneer Venus magnetometer observations. The spacecraft position with respect to the cross-tail current sheet is determined from an observed relationship between the field-draping angle and the magnitude of the field referenced to its value in the nearby magnetosheath. This allows us statistically to remove the effects of tail flapping and variability of draping for the first time and thus to map the average field configuration in the Venus tail. From this average configuration we calculate the cross-tail current density distribution and J × B forces. Continuity of the tangential electric field is utilized to determine the average variations of the X-directed velocity which is shown to vary from −250 km/s at −8 Rv to −470 km/s at −12 Rv. From the calculated J × B forces, plasma velocity, and MHD momentum equation the approximate plasma acceleration, density, and temperature in the Venus tail are determined. The derived ion density is approximately ∼0.07 p+/cm³ (0.005 O+/cm³) in the lobes and ∼0.9 p+/cm³ (0.06 O+/cm³) in the current sheet, while the derived approximate average plasma temperature for the tail is ∼6×106 K for a hydrogen plasma or ∼9×107 K for an oxygen plasma

Deep optical imaging of the field of PC1643+4631A&B, II: Estimating the colours and redshifts of faint galaxies

In an investigation of the cause of the cosmic microwave background decrement in the field of the z = 3.8 quasar pair PC1643+4631, we have carried out a study to photometrically estimate the redshifts of galaxies in deep multi-colour optical images of the field taken with the WHT. To examine the possibility that a massive cluster of galaxies lies in the field, we have attempted to recover simulated galaxies with intrinsic colours matching those of the model galaxies used in the photometric redshift estimation. We find that when such model galaxies are added to our images, there is considerable scatter of the recovered galaxy redshifts away from the model value; this scatter is larger than that expected from photometric errors and is the result of confusion, simply due to ground-based seeing, between objects in the field. We have also compared the likely efficiency of the photometric redshift technique against the colour criteria used to select z>3 galaxies via the strong colour signature of the Lyman-limit break. We find that these techniques may significantly underestimate the true surface density of z>3, due to confusion between the high-redshift galaxies and other objects near the line of sight. We argue that the actual surface density of z=3 galaxies may be as much as 6 times greater than that estimated by previous ground-based studies, and note that this conclusion is consistent with the surface density of high-redshift objects found in the HDF. Finally, we conclude that all ground-based deep field surveys are inevitably affected by confusion, and note that reducing the effective seeing in ground-based images will be of paramount importance in observing the distant universe.Comment: 18 pages, 60 figures, submitted to MNRAS, 2 large figure avaliable at ftp://ftp.mrao.cam.ac.uk:/pub/PC1643/paper2.figure50.eps and ftp://ftp.mrao.cam.ac.uk:/pub/PC1643/paper2.figure51.ep

Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT

Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility. The functional pathways in which these SNPs increase prostate cancer susceptibility are unknown. Finasteride is currently not being used routinely as a chemoprevention agent but the long term outcomes of the PCPT trial are awaited. The outcomes of the SELECT trial have not recommended the use of chemoprevention in preventing prostate cancer. This study investigated whether germline risk SNPs could be used to predict outcomes in the PCPT and SELECT trial. Methods Genotyping was performed in European men entered into the PCPT trial (n = 2434) and SELECT (n = 4885). Next generation genotyping was performed using Affymetrix® Eureka™ Genotyping protocols. Logistic regression models were used to test the association of risk scores and the outcomes in the PCPT and SELECT trials. Results Of the 100 SNPs, 98 designed successfully and genotyping was validated for samples genotyped on other platforms. A number of SNPs predicted for aggressive disease in both trials. Men with a higher polygenic score are more likely to develop prostate cancer in both trials, but the score did not predict for other outcomes in the trial. Conclusion Men with a higher polygenic risk score are more likely to develop prostate cancer. There were no interactions of these germline risk SNPs and the chemoprevention agents in the SELECT and PCPT trials

Ground-state properties and superfluidity of two- and quasi two-dimensional solid 4He

In a recent study we have reported a new type of trial wave function symmetric under the exchange of particles and which is able to describe a supersolid phase. In this work, we use the diffusion Monte Carlo method and this model wave function to study the properties of solid 4He in two- and quasi two-dimensional geometries. In the purely two-dimensional case, we obtain results for the total ground-state energy and freezing and melting densities which are in good agreement with previous exact Monte Carlo calculations performed with a slightly different interatomic potential model. We calculate the value of the zero-temperature superfluid fraction \rho_{s} / \rho of 2D solid 4He and find that it is negligible in all the considered cases, similarly to what is obtained in the perfect (free of defects) three-dimensional crystal using the same computational approach. Interestingly, by allowing the atoms to move locally in the perpendicular direction to the plane where they are confined to zero-point oscillations (quasi two-dimensional crystal) we observe the emergence of a finite superfluid density that coexists with the periodicity of the system.Comment: 16 pages, 8 figure

Discrete Formulation for the dynamics of rods deforming in space

We describe the main ingredients needed to create, from the smooth lagrangian density, a variational principle for discrete motions of a discrete rod, with corresponding conserved Noether currents. We describe all geometrical objects in terms of elements on the linear Atiyah bundle, using a reduced forward difference operator. We show how this introduces a discrete lagrangian density that models the discrete dynamics of a discrete rod. The presented tools are general enough to represent a discretization of any variational theory in principal bundles, and its simplicity allows to perform an iterative integration algorithm to compute the discrete rod evolution in time, starting from any predefined configurations of all discrete rod elements at initial times

Inequalities in Health and Service Use among People with Borderline Intellectual Impairment

This report, produced in collaboration with Professor Angela Hassiotis and others, sets out the extent to which people with borderline intellectual impairment face inequalities in health and use of services compared with the rest of the population, and seeks to improve awareness of these inequalities. Findings - Borderline intellectual impairment is common, affecting at least one adult in ten in England. The term is used here to refer to people with good verbal skills and living in private households, but who may experience cognitive impairments. - The findings in this report are consistent with previous research: people with borderline intellectual impairment are a disadvantaged group and their needs are not well understood. - Such adults face high levels of poor mental health, poorer general health, and many limitations in their daily lives. - Their level of use of mental health treatment and services does not appear to be commensurate with their higher level of need. This indicates that they are underserved compared with the rest of the population. - This may be due to a lack of professional awareness of their needs, to services not adapting enough to meet those needs, or to difficulties the individual faces in seeking treatment and support. - Adults with borderline intellectual impairment constitute key users of primary and secondary health care, and employment, education and welfare support. Improving awareness of the needs of this group should form part of wider plans to reduce inequalities in health and service use in England. Methods Secondary analysis of data from the Adult Psychiatric Morbidity Survey (APMS) was conducted to profile the circumstances of people with borderline intellectual impairment. APMS is one of the most authoritative and comprehensive national household surveys to assess both intellectual functioning and mental health in adults in England

Deep optical imaging of the field of PC1643+4631A&B, I: Spatial distributions and the counts of faint galaxies

We present deep optical images of the PC1643+4631 field obtained at the WHT. This field contains two quasars at redshifts z=3.79 & 3.83 and a cosmic microwave background (CMB) decrement detected with the Ryle Telescope. The images are in U,G,V,R and I filters, and are complete to 25th magnitude in R and G and to 25.5 in U. The isophotal galaxy counts are consistent with the results of Metcalde et al. (1996), Hogg et al. (1997), and others. We find an excess of robust high-redshift Ly-break galaxy candidates with 25.0<R<25.5 compared with the mean number found in the fields studied by Steidel et al. -we expect 7 but find 16 - but we do not find that the galaxies are concentrated in the direction of the CMB decrement. However, we are still not sure of the distance to the system causing the CMB decrement. We have also used our images to compare the commonly used object-finding algorithms of FOCAS and SExtractor: we find FOCAS the more efficient at detecting faint objects and the better at dealing with composite objects, whereas SExtractor's morphological classification is more reliable, especially for faint objects near the resolution limit. More generally, we have also compared the flux lost using isophotal apertures on a real image with that on a noise-only image: recovery of artificial galaxies from the noise-only image significantly overestimates the flux lost from the galaxies, and we find that the corrections made using this technique suffer a systematic error of some 0.4 magnitudes.Comment: 17 pages, 40 figures, submitted to MNRAS, 1 large figure avaliable at ftp://ftp.mrao.cam.ac.uk:/pub/PC1643/paper1.figure18.p

Learning To Be Affected: Social suffering and total pain at life’s borders.

The practice of Live Sociology in situations of pain and suffering is the author’s focus. An outline of the challenges of understanding pain is followed by a discussion of Bourdieu’s ‘social suffering’ (1999) and the palliative care philosophy of ‘total pain’. Using examples from qualitative research on disadvantaged dying migrants in the UK, attention is given to the methods that are improvised by dying people and care practitioners in attempts to bridge intersubjective divides, where the causes and routes of pain can be ontologically and temporally indeterminate and/or withdrawn. The paper contends that these latter phenomena are the incitement for the inventive bridging and performative work of care and Live Sociological methods, both of which are concerned with opposing suffering. Drawing from the ontology of total pain, I highlight the importance of (i) an engagement with a range of materials out of which attempts at intersubjective bridging can be produced, and which exceed the social, the material, and the temporally linear; and (ii) an empirical sensibility that is hospitable to the inaccessible and non-relational

Web-Based Training for an Evidence-Supported Treatment: Training Completion and Knowledge Acquisition in a Global Sample of Learners

The purpose of this investigation is to describe the characteristics of professional and preprofessional learners who registered for and completed TF-CBTWeb, a modular, web-based training program designed to promote the dissemination of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and to demonstrate the feasibility of this method of dissemination. Between October 1, 2005, and October 1, 2012, a total of 123,848 learners registered for TF-CBTWeb, of whom 98,646 (79.7%) initiated the learning activities by beginning the first module pretest. Of those, 67,201 (68.1%) completed the full training. Registrants hailed from 130 countries worldwide, and they had varied educational backgrounds, professional identities (both professional and preprofessional), and a range of experience working with child trauma victims. Learners who were from the United States, students, those with master’s degrees, and those with fewer years of experience working with child trauma victims tended to have the highest course completion rates. Learners displayed significant increases in knowledge about each component of TF-CBT, based on module pretest and posttest scores. The advantages and limitations of this web-based training program evaluation are discussed, while important implications for the use of web-based trainings are reviewed