Harmonization Of Interprofessional Collaboration To Improve The Quality Of Health Care

Cooperation among health workers need to be increased in order to provide better health services in Indonesia as well as develop good cooperating skills among professions. Collaborative services given by health workers will give positive impacts to patient outcome. Good collaboration among health workers can be prepared starting from education level through IPE (Interprofessional Education). IPE is applied to undergraduate students such as medical students, dentistry students, pharmacy students, nutritionist students, public health students, and midwifery students. For literature review and condition analysis, the writer applied a method that requires collecting and analyzing sources such as research articles and other literatures on IPE. IPE itself is an education process with two or more different disciplines used to apply interactive learning process in increasing collaboration and quality of health services and practices of each discipline. By applying IPE on students, it aims to make them learn how to give contribution in a team interprofession through knowledge, skills, and cooperation among teams in providing patients with satisfying health services. Students’ ability to handle conflict and good attitudes in problem solving indicates whether the application of IPE succeeds or not. There are several obstacles in applying IPE on institutions, such as difficulties in time management among health professional students due to differences of the schedule; the lack of academic regulation regulating aligned IPE application; problems in communication among professions; and the lack of interdisciplinary teachers. In conclusion, IPE is an important method that needs to be applied on health students in order to improve collaboration skills among professions and health workers. The methods that can be used in applying IPE are classic lectures, Problem-Based Learning (PBL), and Team Collaboration Health Care (TCHC)

Rotten Sweet Potato (Ipomoea Batatas L.) As An Alternative Source Of Electrical Energy

This research was aimed to find an alternative source of electrical energy from natural materials that are renewable and environmentally friendly. One of them that is potentially to be used as the source of energy is rotten sweet potato. Sweet potatoes (Ipomoea batatas L.) grow in mountainous areas and highlands and are usually used as a carbohydrate replacement of rice by some people. This research was conducted to prove whether sweet potato can be used as alternative energy source or not. The research was begun by slicing rotten sweet potato into small pieces, then crushed using a blender to make an extract of rotten sweet potato. Rotten sweet potato is an electrolyte compound that functions like a battery. To prove the ability as a source of electrical energy, it is necessary to perform redox reaction test. Electrodes used were copper coins and iron tacks. Copper and iron electrodes which were immersed in the sweet potato electrolyte compound caused a redox reaction to be a source of electric current. The results showed that 1 block (3 series circuit) of rotten sweet potato electrolyte can generate 1.5 electric voltage which is equivalent to small batteries. By processing in such a way, the energy of rotten sweet potato can be developed to become a source of electricity for lighting a house. This can certainly be useful for villagers who have a high enough level of sweet potato consumption resulting abundant sweet potato waste that can be utilized

Anti-viral activity of Phyllanthus niruri against hepatitis C virus

Hepatitis C virus (HCV) infection is a global problem that causes liver disease and hepatocellular carcinoma. Although the current standard treatment provided a significant improvement on response rate with sustain virology response more than 90%, however, the high cost was remaining limited access to this therapy, resistance emergence and serious side effects which provide the necessities to find the new anti-HCV agents. The current study, we evaluated the ethanol extract of Phyllanthus niruri for its anti-HCV activities. Anti-HCV activity was determined by in vitro culture cells of Huh 7it. Anti-HCV activity of P. niruri extract revealed strong inhibition against HCV with IC50 values of 4.14 µg/mL and yield stronger activity in the entry step of the HCV life cycle. Moreover, the P. niruri extract enhanced anti-HCV activity of simeprevir (NS3 protease inhibitor) with increase the activity up to 4-fold compared to a single treatment of simeprevir. Docking analysis was performed to predict the interaction phyllanthin and hypophyllantin, known compounds of P. niruri against HCV receptor. Both of phyllantin and hypophyllantin were mediated a strong interaction with 4GAG, a protein that involved in entry step of HCV. These results suggested that the ethanol extract of P. niruri may be good candidates for the development of anti-HCV drugs

Drug Utilization Study Of Diuretics In Hepatic Cirrhosis Patient With Ascites At Airlangga University Hospital Surabaya

Ascites is an accumulation of fluid in the peritoneal space and one of the first signs of decompensation of liver disease. Ascites is one of the complications experienced by patients with hepatic cirrhosis. Therapy commonly used for ascites is diuretics, along with salt restriction in the diet. Potassium-sparing diuretics, especially spironolactone and loop diuretics, especially furosemide, are the main pharmacological therapies for ascites. The purpose of this study was to examine the characteristics distribution of hepatic cirrhosis patients, to assess the profile of the use of diuretic drugs during hospitalization, and to determine the possibility of a Drug Related Problem (DRP) on diuretic therapy for patients with ascites at Airlangga University Hospital (RSUA) Surabaya. The research was conducted with non-experimental methods or observations, it was subsequently analyzed descriptively. Data collection was carried out in non-random and time limited sampling in the period of 1 January 2013 - 31 March 2017 in the Inpatient Room of Internal Medicine Department at RSUA Surabaya and was declared as ethically feasible. Based on the results of 45 SH samples with complications of ascites, the most common characteristics of hepatic cirrhosis patients were men by 53.33%, the highest age range was 45-64 years at 75.56%, while the highest complication was hypoalbumin with the percentage of 26.67% and the longest treatment duration was 6-10 days at 46.67%.The therapeutic profile of diuretics in this study, namely the use of furosemide as a single therapy with the percentage of 17.78% and single spironolactone therapy of 2.22% and combination therapy of spironolactone with furosemide with the percentage of 80.00 %. The most widely used furosemide was intravenous use with a daily dose of 1x20mg 57.78%, while spironolactone was the most widely used in oral use with a daily dose of 1x100mg 44.44%. Drug Related Problems (DRP) that occuedr including potential drug interactions found in concomitant use between spironolactone and potassium preparations with the percentage of 24.44%. No actual drug interactions and side effects were found in this study.

Pemberdayaan Ekonomi Pemuda melalui program Jaringan warung Nusantara (Jawara) Himpunan Pengusaha Nahdliyin di kelurahan Jatisari Kecamatan Jatiasih Kota Bekasia

Muhammad Dzul Azmi Pemberdayaan Ekonomi Pemuda Melalui Program Jaringan Warung Nusantara (jawara) oleh Himpunan Pengusaha Nahdiyin di Kelurahan Jatisari Kecamatan Jatiasih Kota Bekasi Pembangunan adalah upaya untuk memberdayakan masyarakat agar tercipta suatu lingkungan yang memungkinkan masyarakat dapat menikmati kualitas kehidupan yang lebih baik. Pembangunan daerah dilaksanakan pengelolaan sumber daya yang mengarah pada pemerintahan yang lebih baik. Pembangunan daerah yang baik dapat terjadinya keseimbangan antara pemerintah, dunia usaha dan masyarakat. Namun masalah dari pembangunan baik di negara maju maupun di negara berkembang adalah pengangguran. Negara dituntut untuk menciptakan pembangunan dan kesempatan kerja untuk penduduknya. Dampak dari pengangguran masyarakat tidak dapat memaksimalkan kesejahteraan yang dicapai. Peran pemerintah dalam pembangunan sangat dibutuhkan agar tidak terjadi kesenjangan sosial di masyarakat Peran Himpunan Pengusaha Nahdliyin di kota bekasi, di harapakan dapat menarik minat para pemuda khususnya dan para waga Nahdliyin di Kota Bekasi untuk mengikuti berbagai macam program yang sudah di susun oleh pihak Himpunan Pengusaha Nahdliyin Kota Bekasi, Khususnya pada permaslahan ini adalah program Jawara (Jaringan Warung Nusantara) yang mana pokok sasaranya adalah para pemuda yang tidak memiliki kegiatan, pengangguran, dan kurang mencukupi dalam gal ekomomi. Harapan pemberi program sendiri yaitu bertujuan agar masyarakat mampu membangun kehidupannya secara layak dan program yang diberikan tersebut memiliki kesesuaian dengan kemampuan dan potensi yang di miliki masyarakat. Penelitian ini menggunakan pendekatan kualitatif yaitu prosedur penelitian yang menghasilkan data deskriptif berupa kata-kata tertulis atau lisan dari orangorang dan perilaku yang diamati. Subjek penelitian adalah orang yang dapat memberikan informasi, adapun yang dijadikan sumber informasi dalam penelitian ini adalah Ketua Umum HPN Kota Bekasi dan Ketua Harian HPN Kota Bekasi. Sedangkan objeknya adalah tentang peran HPN dalam pemberdayaan masyarakat melalui program jaringan warung nusantara (Jawara). Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Hasil penelitian yang penulis temukan terkait dengan Peran Himpunan Pengusaha Nahdliyin dalam pemberdayaan masyarakat melalui program jawara adalah berperan melaksanakan tugas dan kewajibannya sebagai fasilitator dan pendidik yang mengupayakan agar kehidupan masyarakat menjadi mandiri.91 hlm

AKTIVITAS ANTIVIRUS HEPATITIS C EKSTRAK ETANOL 96% HERBA Phyllanthus niruri L. DAN KOMBINASI SIMEPREVIR IN VITRO

Hepatitis C virus (HCV) infection is the main cause of chronic liver disease, such as cirrhosis and liver cancer. Currently, the standard of hepatitis C virus treatment has been highly developed and achieved the level of Sustained Virological Response (SVR) more than 90%. However, the possibility of resistance and the high cost of treatment also need to be considered. This is due to the fact that both of them are one of the causes of hepatitis C therapy failure, especially in populations with relatively low income. Therefore, it is necessary to develop safe, inexpensive and more effective drug therapy for HCV infection. The current study, we conducted an anti-hepatitis C activity test from the ethanol extract of Phyllanthus niruri L. by in vitro culture cells using Huh7it cells. The results were found that IC50 of P. niruri is 6.2 ± 0.6 μg / ml which worked more dominantly in the entry step stage of HCV life cycle based on the MOA (Mode of Action) analysis. In addition, combination test of P. niruri and anti-hepatitis C drug of simeprevir was also carried out by adding 25 μg/ml of P. niruri extract and further confirm with the Chou- Talalay method analysis. The result of the combination test by adding 25 μg/ml extract was found that P. niruri extract is able to increase an activity of simeprevir up to 3-fold (IC50 : 3.4 ± 1.1 nM) compared to a single treatment of simeprevir (IC50 : 10.8 ± 1.3 nM). Besides, the result of Chou-Talalay method was found that P. niruri extract is able to increase an activity of simeprevir up to 2-fold (IC50 : 4.0 ± 0.1 nM) compared to a single treatment of simeprevir (IC50 : 8.0 ± 0.2 nM). In addition, the results of the combination test also demonstrated that P. niruri extract worked synergistically with simeprevir as indicated by the Combination Index (CI) less than 1 (0.865). To ensure the safety of all samples, a cytotoxicity test was conducted and the results shown that all of the samples were not cytotoxic as indicated by the percentage of cell viability more than 95%. From these results, it can be concluded that the P. niruri extract can be a strong candidate in dealing with the problem of hepatitis C virus infection

A Prediction for the Conversion Performance of H₂S to Elemental Sulfur in an Ionic-Liquid-Incorporated Transition Metal Using COSMO-RS

In the present study, the conversion performance of hydrogen sulfide (H2S) to elemental sulfur in ionic-liquid-incorporated transition metals (ILTMs) is predicted using a conductor-like screening model for realistic solvents (COSMO-RS). The predictions were made via the establishment of a correlation between the conversion performance and solubility of H2S in ionic liquids (ILs). All molecules involved were optimized at the DFT/TZVP/M06 computational level and imported on the COSMOtherm program at equimolar conditions. For validation purposes, the solubility of ILs was predicted at 1 bar pressure. Simple regression analysis was used to establish a relationship between the solubility and conversion performance of H2S. The results indicate that the solubility prediction of ILs is accurate (R2 = 93.40%) with a p-value of 0.0000000777. Additionally, the conversion performance is generally found to be dependent on the solubility value. Furthermore, 1-butyl-3-methylimidazolium chloride [bmim][Cl] was chosen as the base IL for incorporating the transition metal, owing to its solubility and selectivity to H2S. The solubility trend of ILTMs is found to follow the following order: [bmim][NiCl3] > [bmim][FeCl4] > [bmim][CoCl3] > [bmim][CuCl3]. According to the viscosity measurements of ILTMs, [bmim][NiCl3] and [bmim][FeCl4] exhibited the highest and lowest viscosity values, respectively. Therefore, [bmim][FeCl4] is a promising ILTM owing to its higher solubility and low viscosity for the application studied

A Prediction for the Conversion Performance of H2S to Elemental Sulfur in an Ionic-Liquid-Incorporated Transition Metal Using COSMO-RS

In the present study, the conversion performance of hydrogen sulfide (H2S) to elemental sulfur in ionic-liquid-incorporated transition metals (ILTMs) is predicted using a conductor-like screening model for realistic solvents (COSMO-RS). The predictions were made via the establishment of a correlation between the conversion performance and solubility of H2S in ionic liquids (ILs). All molecules involved were optimized at the DFT/TZVP/M06 computational level and imported on the COSMOtherm program at equimolar conditions. For validation purposes, the solubility of ILs was predicted at 1 bar pressure. Simple regression analysis was used to establish a relationship between the solubility and conversion performance of H2S. The results indicate that the solubility prediction of ILs is accurate (R2 = 93.40%) with a p-value of 0.0000000777. Additionally, the conversion performance is generally found to be dependent on the solubility value. Furthermore, 1-butyl-3-methylimidazolium chloride [bmim][Cl] was chosen as the base IL for incorporating the transition metal, owing to its solubility and selectivity to H2S. The solubility trend of ILTMs is found to follow the following order: [bmim][NiCl3] > [bmim][FeCl4] > [bmim][CoCl3] > [bmim][CuCl3]. According to the viscosity measurements of ILTMs, [bmim][NiCl3] and [bmim][FeCl4] exhibited the highest and lowest viscosity values, respectively. Therefore, [bmim][FeCl4] is a promising ILTM owing to its higher solubility and low viscosity for the application studied

Critical success factor for sustainable frozen food

Industrial production of frozen food is the food industries that develop rapidly and it is not something new to consumers in Malaysia.Frozen food industry has captured the hearts of consumers to various products offered in the market nowadays. In view of that, this study analyses the critical success factors for sustainable frozen food industry. In this study there are four factors related in critical success sustainable frozen food industry such as food security.Therefore frozen food manufacture must make sure that their food was safe and clean to customer use, this issue always happen in frozen food industrial.The research design has been done with the technique qualitative and quantitative.Besides using a survey to gather customer perceptions, this research also employs key personnel perspectives into the analysis. It is expected that the findings could contribute towards greater understanding in view of frozen food industry. This research is also expected to provide good insights on managerial applications