The evolution of a Ku-Band satellite network

The purpose of this study was to undertake the management and development of CTS terminals and time on appropriate Ku-Band satellites was procured. A community of public service users who have readily addressable needs and resources to pay for services on an ad hoc Ku-Band network was developed and a test network for selected users was managed

Heasim and Skyback Simulation Tools and Their Application to the Hitomi Mission

We present an introduction to the heasim multimission observation and skyback background, high-energy pseudo Monte Carlo astrophysical simulation tools. Heasim may be used to accurately and efficiently construct flexible image transport system (FITS) event files for simple or composite sources with a wide range of standard and user-defined spatial, spectral, and temporal characteristics. Skyback is designed to enable users to assess the impact of background discrete and diffuse emission on prospective observations, and skyback output may be directly input into heasim. We present a brief overview of heasim and skyback input, algorithms, usage, and output. We also introduce the sxsbranch tool that computes Hitomi soft X-ray spectrometer resolution grade branching ratios, emphasizing its application to simulations. We include several examples of particular relevance to the Hitomi mission

The Micro-Arcsecond Scintillation-Induced Variability (MASIV) Survey II: The First Four Epochs

We report on the variability of 443 flat spectrum, compact radio sources monitored using the VLA for 3 days in 4 epochs at ~ 4 month intervals at 5 GHz as part of the Micro-Arcsecond Scintillation-Induced Variability (MASIV) survey. Over half of these sources exhibited 2-10% rms variations on timescales over 2 days. We analyzed the variations by two independent methods, and find that the rms variability amplitudes of the sources correlate with the emission measure in the ionized Interstellar Medium along their respective lines of sight. We thus link the variations with interstellar scintillation of components of these sources, with some (unknown) fraction of the total flux density contained within a compact region of angular diameter in the range 10-50 micro-arcseconds. We also find that the variations decrease for high mean flux density sources and, most importantly, for high redshift sources. The decrease in variability is probably due either to an increase in the apparent diameter of the source, or a decrease in the flux density of the compact fraction beyond z ~ 2. Here we present a statistical analysis of these results, and a future paper will the discuss the cosmological implications in detail.Comment: 62 pages, 13 figures. Accepted for publication in the Astrophysical Journa

Glucagon-like peptide-1 protects against ischemic left ventricular dysfunction during hyperglycemia in patients with coronary artery disease and type 2 diabetes mellitus.

BACKGROUND: Enhancement of myocardial glucose uptake may reduce fatty acid oxidation and improve tolerance to ischemia. Hyperglycemia, in association with hyperinsulinemia, stimulates this metabolic change but may have deleterious effects on left ventricular (LV) function. The incretin hormone, glucagon-like peptide-1 (GLP-1), also has favorable cardiovascular effects, and has emerged as an alternative method of altering myocardial substrate utilization. In patients with coronary artery disease (CAD), we investigated: (1) the effect of a hyperinsulinemic hyperglycemic clamp (HHC) on myocardial performance during dobutamine stress echocardiography (DSE), and (2) whether an infusion of GLP-1(7-36) at the time of HHC protects against ischemic LV dysfunction during DSE in patients with type 2 diabetes mellitus (T2DM). METHODS: In study 1, twelve patients underwent two DSEs with tissue Doppler imaging (TDI)-one during the steady-state phase of a HHC. In study 2, ten patients with T2DM underwent two DSEs with TDI during the steady-state phase of a HHC. GLP-1(7-36) was infused intravenously at 1.2 pmol/kg/min during one of the scans. In both studies, global LV function was assessed by ejection fraction and mitral annular systolic velocity, and regional wall LV function was assessed using peak systolic velocity, strain and strain rate from 12 paired non-apical segments. RESULTS: In study 1, the HHC (compared with control) increased glucose (13.0 ± 1.9 versus 4.8 ± 0.5 mmol/l, p < 0.0001) and insulin (1,212 ± 514 versus 114 ± 47 pmol/l, p = 0.01) concentrations, and reduced FFA levels (249 ± 175 versus 1,001 ± 333 μmol/l, p < 0.0001), but had no net effect on either global or regional LV function. In study 2, GLP-1 enhanced both global (ejection fraction, 77.5 ± 5.0 versus 71.3 ± 4.3%, p = 0.004) and regional (peak systolic strain -18.1 ± 6.6 versus -15.5 ± 5.4%, p < 0.0001) myocardial performance at peak stress and at 30 min recovery. These effects were predominantly driven by a reduction in contractile dysfunction in regions subject to demand ischemia. CONCLUSIONS: In patients with CAD, hyperinsulinemic hyperglycemia has a neutral effect on LV function during DSE. However, GLP-1 at the time of hyperglycemia improves myocardial tolerance to demand ischemia in patients with T2DM. TRIAL REGISTRATION: http://www.isrctn.org . Unique identifier ISRCTN69686930

Unusual Flaring Activity in the Blazar PKS 1424-418 during 2008-2011

Context. Blazars are a subset of active galactic nuclei (AGN) with jets that are oriented along our line of sight. Variability and spectral energy distribution (SED) studies are crucial tools for understanding the physical processes responsible for observed AGN emission. Aims. We report peculiar behaviour in the bright gamma-ray blazar PKS 1424-418 and use its strong variability to reveal information about the particle acceleration and interactions in the jet. Methods. Correlation analysis of the extensive optical coverage by the ATOM telescope and nearly continuous gamma-ray coverage by the Fermi Large Area Telescope is combined with broadband, time-dependent modeling of the SED incorporating supplemental information from radio and X-ray observations of this blazar. Results. We analyse in detail four bright phases at optical-GeV energies. These flares of PKS 1424-418 show high correlation between these energy ranges, with the exception of one large optical flare that coincides with relatively low gamma-ray activity. Although the optical/gamma-ray behaviour of PKS 1424-418 shows variety, the multiwavelength modeling indicates that these differences can largely be explained by changes in the flux and energy spectrum of the electrons in the jet that are radiating. We find that for all flares the SED is adequately represented by a leptonic model that includes inverse Compton emission from external radiation fields with similar parameters. Conclusions. Detailed studies of individual blazars like PKS 1424-418 during periods of enhanced activity in different wavebands are helping us identify underlying patterns in the physical parameters in this class of AGN.Comment: accepted for publication in A&

Interstellar scintillation, AGN physics and the SKA

A large fraction of compact, extragalactic radio sources exhibit rapid variability at centimetre wavelengths as their radio emission is scattered by electron density fluctuations in the interstellar medium of the Galaxy. Next-generation wide-field radio telescopes will have to account for this in forming deep images of the radio sky. Interstellar scintillation offers a unique probe of very small-scale structure in both the ionized interstellar medium and the compact jets of the radio sources themselves. The effective resolution is two orders of magnitude higher than achievable with very long baseline interferometry. The recent Micro-Arcsecond Scintillation-Induced Variability Survey revealed a reduction in ISS at 4.9 GHz with increasing source redshift, implying either an increase in the apparent angular size of high-redshift radio cores beyond that expected due to a cosmological decrease in brightness, or a decrease in the microarcsecond-scale core dominance towards high redshift. The result could be due either to source-intrinsic evolution in the selected sample, or to scatter-broadening in the intergalactic medium

TANAMI - Tracking Active Galactic Nuclei with Austral Milliarcsecond Interferometry

We present a summary of the observation strategy of TANAMI (Tracking Active Galactic Nuclei with Austral Milliarcsecond Interferometry), a monitoring program to study the parsec-scale structure and dynamics of relativistic jets in active galactic nuclei (AGN) of the Southern Hemisphere with the Australian Long Baseline Array (LBA) and the trans-oceanic antennas Hartebeesthoek, TIGO, and O'Higgins. TANAMI is focusing on extragalactic sources south of -30 degrees declination with observations at 8.4 GHz and 22 GHz every ~2 months at milliarcsecond resolution. The initial TANAMI sample of 43 sources has been defined before the launch of the Fermi Gamma Ray Space Telescope to include the most promising candidates for bright gamma-ray emission to be detected with its Large Area Telescope (LAT). Since November 2008, we have been adding new sources to the sample, which now includes all known radio- and gamma-ray bright AGN of the Southern Hemisphere. The combination of VLBI and gamma-ray observations is crucial to understand the broadband emission characteristics of AGN and the nature of relativistic jets.Comment: Conference proceedings "2009 Fermi Symposium" eConf Proceedings C09112

The TANAMI Program

TANAMI (Tracking Active Galactic Nuclei with Austral Milliarcsecond Interferometry) is a monitoring program to study the parsec-scale structures and dynamics of relativistic jets in active galactic nuclei (AGN) of the Southern Hemisphere with the Long Baseline Array and associated telescopes. Extragalactic jets south of -30 degrees declination are observed at 8.4 GHz and 22 GHz every two months at milliarcsecond resolution. The initial TANAMI sample is a hybrid radio and gamma-ray selected sample since the combination of VLBI and gamma-ray observations is crucial to understand the broadband emission characteristics of AGN.Comment: Confernce Proceedings for "X-ray Astronomy 2009" (Bologna), 3 pages, 3 figures, needs cls-fil