A Concise Review of the Multimodality Imaging Features of Renal Cell Carcinoma

The evaluation of renal cell carcinoma (RCC) is routinely performed using the multimodality imaging approach, including ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET). Ultrasonography is the most frequently used imaging modality for the initial diagnosis of renal masses. The modality of choice for the characterization of the renal mass is multiphasic CT. Recent advances in CT technology have led to its widespread use as a powerful tool for preoperative planning, reducing the need for catheter angiography for the evaluation of vascular invasion. CT is also the standard imaging modality for staging and follow-up. MRI serves as a problem-solving tool in selected cases of undefined renal lesions. Newer MRI techniques, such as arterial spin labeling and diffusion-weighted imaging, have the potential to characterize renal lesions without contrast media, but these techniques warrant further investigation. PET may be a useful tool for evaluating patients with suspected metastatic disease, but it has modest sensitivity in the diagnosis and staging of RCC. The newer radiotracers may increase the accuracy of PET for RCC diagnosis and staging. In summary, the main imaging modality used for the characterization, staging, and surveillance of RCC is multiphasic CT. Other imaging modalities, such as MRI and PET, are used for selected indications

Computed Tomography Imaging Findings of Acute Aortic Pathologies

Acute aortic syndromes (AAS) encompass a spectrum of life-threatening conditions characterized by acute aortic pain. AAS include acute aortic dissection, intramural hematoma, penetrating atherosclerotic ulcer, and aneurysm rupture. The prognosis of AAS is clearly related to prompt diagnosis and appropriate management. The different types of AAS cannot be reliably differentiated solely based on clinical presentation since the clinical features are indistinguishable. Multidetector-row computed tomography (MDCT) with electrocardiographic gating (ECG-gated MDCT) has been used in the acute emergency setting as a powerful clinical tool, which enables rapid and specific diagnosis of aortic pathologies. ECG-gated MDCT significantly reduces motion artifact and avoids potential pitfalls in the diagnosis of AAS. The aim of this review is to evaluate the role of MDCT imaging in the assessment of AAS and to discuss the differentiation of this spectrum of aortic diseases with reference to the key imaging findings

Determination and evaluation of acidity constants of some imidazole and thiazole linked acetamide compounds

In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated. The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric method. When the molecules possessed different substituents the values of the acidity constants changed from 6.01 to 8.22 for the first protonation and from 3.07 to 4.73 for the second protonation. The first protonation under these circumstances was observed to occur on the nitrogen atom of the 2-mercaptoimidazole ring. The second protonation was observed to occur on the nitrogen atom of the thiazole ring

Prevalence of Poor Sleep Quality and Its Determinants Among Men Suffering from Erectile Dysfunction

Objective:Recent findings implicate a higher prevalence of erectile dysfunction (ED) among men with sleep disorders. We investigated sleep quality among men with ED.Materials and Methods:A prospective study was conducted at 12 different andrology outpatient clinics among men with complaints of insufficient erections. The subjective quality of sleep was measured using the Pittsburgh Sleep Quality Inventory. Erectile function and its dimensions were measured using the International Index of Erectile Function (IIEF) questionnaire. The age-adjusted Charlson comorbidity index and Beck Depression Inventory were used to evaluate interrelations with comorbid disease severity and depression of the subjects consecutively in the study.Results:Among 431 eligible men, the median age of the participants and their erectile function scores in the IIEF were 51 [interquartile range (IQR)=43-59] and 16 (IQR=11-19), respectively. Poor sleep was observed in 192 of 431 (44.5%) subjects. Multivariable analysis revealed that younger age [odds ratio (OR)=0.95, p=0.01], lower body mass (OR=0.86, p=0.01), lower serum high-density lipoprotein cholesterol (OR=0.95, p=0.02), and higher severity of depression (OR=2.1, p=0.0001) were predictors of poor sleep quality among men with ED.Conclusion:Nearly half of the men with ED also suffer from poor sleep. Younger age, lean body mass, and severe depression were the main predictors of poor sleep quality among ED sufferers

Süleyman Paşa’nın Divan-ı Harp’te yargılanmasına dair defterin transkripsiyonu ve değerlendirmesi (1878-1879)

Bu çalışmanın konusunu, 93 Harbi olarak bilinen 1877–1878 Osmanlı-Rus Savaşı’nda Rumeli orduları umum kumandanı olan Süleyman Paşa’nın Divan-ı Harp’te yargılanmasına dair Başbakanlık Osmanlı Arşivi Yıldız Esas Evrakı 999 numaralı defterin transkripsiyonu oluşturmaktadır. Osmanlıca’dan basit transkripsiyon yöntemi ile Latin harflerine aktarılan eserin transkripsiyonu esnasında orjinaline sadık kalındı. Çalışmanın giriş kısmında, Süleyman Paşa’nın yargılanmasına neden olan 93 harbinin sebepleri, o dönemin uluslar arası konjonktürü ile devletlerarası münasebetler ve savaşa götüren sebepler anlatıldı. Birinci bölümde, Süleyman Paşa’nın hayatı anlatıldıktan sonra defterdeki yargılama sürecine ait konuların mahiyetinde genel bir değerlendirilmesi yapıldı. Tezin ikinci bölümünde ise defterin trankripsiyonu verildi. Eserin sonuç kısmında, defterdeki bilgilere ilave olarak Süleyman Paşa hakkında padişah iradesi ile beraber yargılanmasına götüren zahiri sebeplerin yanında gerçek sebeplerin de ne olabileceği konusunda açıklamalar yapıldı. ABSTRACT The topic of this work consists of the notebook transcription of the Ottoman Archives of Prime Ministry which named as Yıldız Esas document no:999, about the trial of Suleyman Pasha at the supreme military court who was the commander of the Rumeli armies of the Ottoman Army during the Ottoman-Russian War between 1877-1878 known as 93 War. The accuracy kept according to it’s original Ottoman language while translating by simple transcription method to Latin alphabet. At the intruduction part of the work, it is told about the reasons of the 93 War, reasoned with the trial of the Suleyman Pasha, the international conjuncture of those times and inter-states relations and the reasons of the war. After the explanation in the first part about the life story of Suleyman Pasha, a general evaluation of the trial process in the notebook made as an abstract. The second part of the thesis gave us the transcription of the notebook. At the last part of the work, additionaly to the information about Suleyman Pasha, the artificial reasons, took him to the court with the will of the Padishah and real reasons explained

Halkapınar Spor Salonunun sismik çatı izalasyonu.

In this study, seismic roof isolation solutions were investigated with a case study of Halkapınar Gymnasium, izmir. In the first part, seismic isolation was explanied and philosophy behind it was given. In the second part, existing seismic roof isolators, elastomeric bearing and viscous damper, were investigated with different support isolation combinations. In the third part, two more types of seismic isolators, lead rubber bearing and friction pendulum isolators, were also analyzed by using the same model and all results were compared with each other and that of non-isolated roof system. Furthermore, bilinear effect of the non-linear isolators were also studied. Finally, all results were compared with each other considering structure responses and effectiveness of the seismic isolators. It has been tried to find the most efficient seismic isolation solution for Halkapınar Gymnasium. .M.S. - Master of Scienc

Evaluation of coronary arteries by multidetector computed tomography

Koroner arter hastalığının değerlendirilmesinde kateter anjiyografi altın standart olarak kabul edilmekle birlikte, asemptomatik ve hafif semptomatik fazdaki koroner arter hastalığının takibi ve değerlendirilmesinde invaziv olmayan görüntüleme yöntemlerine ihtiyaç duyulmaktadır. Bu açıdan, çokkesitli bilgisayarlı tomografi (BT) teknolojisinin gelişmesiyle, koroner BT anjiyografi koroner arterlerin görüntülenmesinde yüksek potansiyele sahip bir yöntem olarak kullanılmaya başlanmıştır. Bu derlemede koroner BT teknolojisi, klinik uygulama alanları, endikasyonları ve bu konuda yapılmış çalışmalar gözden geçirildi.Although coronary angiography is recognized as the gold standard in the evaluation of coronary artery disease, there is still need for noninvasive imaging methods to detect and monitor asymptomatic or minimally symptomatic coronary artery disease. With technological improvements in multidetector computed tomography (CT), coronary CT angiography proved to be a potential noninvasive method in this field. This article reviews technological aspects, clinical applications, and indications of coronary CT angiography in the light of the most recent literature

Tricuspid valve mass: magnetic resonance imaging findings--case report

İstanbul Bilim Üniversitesi, Tıp Fakültesi.Manyetik rezonans (MRI) ile görüntüleme tekniği, radyoaktif yayılım olmadan, noninvazif bir şekilde manyetik radyo dalgaları ile yapılan bir görüntüleme tekniğidir. Diğer standart noninvazif metodlar arasında ekokardiyografi ve bilgisayarlı› tomografi (BT) sayılabilir

Constrictive pericarditis impressing and narrowing the ascending aorta

WOS: 000258400000015PubMed ID: 18754936A 77-year-old male patient was admitted to our institution with 1-year history of progressive dyspnea on exertion, and lower extremity edema. His chest x-ray showed a circumferential pericardial calcification and right-sided pleural effusion. The electrocardiography revealed atrial fibrillation with low voltage in all derivations and diffuse nonspecific T-wave inversions. The transesophageal echocardiography showed a thickened pericardium with biatrial enlargement and normal right and left ventricular systolic functions. A thick echogenic structure that caused impression and narrowing of the ascending aorta was observed. Simultaneous right and left heart catheterization showed elevation and equalization of right-sided and left-sided diastolic filling pressures, with characteristic dip and plateau. Aortic angiogram showed the ascending aorta was impressed and narrowed by calcified pericardium. Cine magnetic resonance imaging showed pericardial calcifications impressing and narrowing of the ascending aorta. All these findings were consistent with constrictive pericarditis. The patient had no history of tuberculosis, cardiac surgery, or mediastinal irradiation. His HIV antibody test was negative. Marked pericardial thickening and calcifications were evident during pericardiectomy. Histological analysis of the pericardium showed dense collageneous matrix, mild chronic inflammation and calcification. The culture of pericardial tissue revealed no identifiable cause including tuberculosis. The patient was diagnosed as idiopathic constrictive pericarditis. The patient's symptoms and edema decreased remarkably after pericardial stripping. He remained well at 1-year follow-up