Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic

Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a specific phenotype. Because linkage and association analysis provide complementary information, developing a method to combine these analyses may increase the power to detect a true association. In this paper we compare a linkage score and association score test as well as a newly proposed combination of these two scores with traditional linkage and association methods.National Institutes of Health (National Institute of General Medical Sciences R01 GM031575, National Center for Research Resources Shared Instrumentation grant 1S10RR163736-01A1

Aging, rejuvenation and memory effects in re-entrant ferromagnets

We have studied the slow dynamics of the ferromagnetic phases of the re-entrant CdCr_{2x}In_{2-2x}S_4 system for 0.85<x<=1 by means of low frequency ac susceptibility and magnetization measurements. Experimental procedures widely used in the investigation of the out-of-equilibrium dynamics of spin glasses (such as the x=0.85 compound) have been applied to search for aging, rejuvenation and memory effects, and to test their dependence on the disorder introduced by dilution of the magnetic ions. Whereas the rejuvenation effect is found in all studied samples, the memory effect is clearly enhanced for increasing dilutions. The results support a description of aging in both ferromagnetic and re-entrant spin-glass phases in terms of hierarchical reconformations of domain walls pinned by the disorder.Comment: Service de Physique de l'Etat Condense, DRECAM, DSM, CEA Saclay,91191 Gif sur Yvette Cedex, France, 9 pages, including 7 figures, To appear in Eur. Phys. J. B (2002

Lifting SU(2) Spin Networks to Projected Spin Networks

Projected spin network states are the canonical basis of quantum states of geometry for the most recent EPR-FK spinfoam models for quantum gravity. They are functionals of both the Lorentz connection and the time normal field. We analyze in details the map from these projected spin networks to the standard SU(2) spin networks of loop quantum gravity. We show that this map is not one-to-one and that the corresponding ambiguity is parameterized by the Immirzi parameter. We conclude with a comparison of the scalar products between projected spin networks and SU(2) spin network states.Comment: 14 page

Rheology of cholesteric blue phases

Blue phases of cholesteric liquid crystals offer a spectacular example of naturally occurring disclination line networks. Here we numerically solve the hydrodynamic equations of motion to investigate the response of three types of blue phases to an imposed Poiseuille flow. We show that shear forces bend and twist and can unzip the disclination lines. Under gentle forcing the network opposes the flow and the apparent viscosity is significantly higher than that of an isotropic liquid. With increased forcing we find strong shear thinning corresponding to the disruption of the defect network. As the viscosity starts to drop, the imposed flow sets the network into motion. Disclinations break-up and re-form with their neighbours in the flow direction. This gives rise to oscillations in the time-dependent measurement of the average stress.Comment: 4 pages, 4 figure

Field induced anisotropic cooperativity in a magnetic colloidal glass

The translational dynamics in a repulsive colloidal glass-former is probed by time-resolved X-ray Photon Correlation Spectroscopy. In this dense dispersion of charge-stabilized and magnetic nanoparticles, the interaction potential can be tuned, from quasi-isotropic to anisotropic by applying an external magnetic field. Structural and dynamical anisotropies are reported on interparticle lengthscales associated with highly anisotropic cooperativity, almost two orders of magnitude larger in the field direction than in the perpendicular direction and in zero field

Alien Registration- Dupuis, Joseph E. (Beddington, Washington County)

https://digitalmaine.com/alien_docs/1627/thumbnail.jp

Spin Anisotropy and Slow Dynamics in Spin Glasses

We report on an extensive study of the influence of spin anisotropy on spin glass aging dynamics. New temperature cycle experiments allow us to compare quantitatively the memory effect in four Heisenberg spin glasses with various degrees of random anisotropy and one Ising spin glass. The sharpness of the memory effect appears to decrease continuously with the spin anisotropy. Besides, the spin glass coherence length is determined by magnetic field change experiments for the first time in the Ising sample. For three representative samples, from Heisenberg to Ising spin glasses, we can consistently account for both sets of experiments (temperature cycle and magnetic field change) using a single expression for the growth of the coherence length with time.Comment: 4 pages and 4 figures - Service de Physique de l'Etat Condense CNRS URA 2464), DSM/DRECAM, CEA Saclay, Franc

Aging phenomena in spin glass and ferromagnetic phases: domain growth and wall dynamics

We compare aging in a disordered ferromagnet and in a spin glass, by studying the different phases of a reentrant system. We have measured the relaxation of the low-frequency ac susceptibility, in both the ferromagnetic and spin-glass phases of a CdCr_{1.9}In_{0.1}S_4 sample. A restart of aging processes when the temperature is lowered (`chaos-like' effect) is observed in both phases. The memory of previous aging at a higher temperature can be retrieved upon re-heating, but in the ferromagnetic phase it can rapidly be erased by the growth of ferromagnetic domains. We interpret the behaviour observed in the ferromagnetic phase in terms of a combination of domain growth and pinned wall reconformations, and suggest that aging in spin glasses is dominated by such wall reconformation processes.Comment: SPEC, CEA Saclay, 91191 Gif sur Yvette Cedex, France, to appear in Europhys. Lett. (2000

Usage of Specialized Fence-Gaps in a Black Rhinoceros Conservancy in Kenya

Fencing is increasingly used in wildlife conservation. Keeping wildlife segregated from local communities, while permitting wildlife access to the greater landscape matrix is a complex task. We investigated the effectiveness of specially designed fence-gaps on animal movement at a Kenyan rhinoceros conservancy, using camera-traps over a four-year period. The fence-gap design restricted the movement of black (Diceris bicornis) and white rhinoceroses (Ceratotherium simum simum) but permitted the movement of other species. We documented over 6000 crossing events of over 50 000 individuals which used the fence-gaps to enter or leave the conservancy. We recorded 37 mammal species and two species of bird using the fence-gaps. We conclude that this fence-gap design is effective at restricting rhinoceros movement and at permitting other wildlife movement into and out of the conservancy. We recommend that fenced-in rhinoceros conservancies that desire enhanced connectivity consider this fence-gap design to help re-connect their reserves to the outside landscape matrix while continuing to provide enhanced protection for their rhinoceroses

Holomorphic Simplicity Constraints for 4d Riemannian Spinfoam Models

Starting from the reformulation of the classical phase space of Loop Quantum Gravity in terms of spinor variables and spinor networks, we build coherent spin network states and show how to use them to write the spinfoam path integral for topological BF theory in terms of Gaussian integrals in the spinors. Finally, we use this framework to revisit the simplicity constraints reducing topological BF theory to 4d Riemannian gravity. These holomorphic simplicity constraints lead us to a new spinfoam model for quantum gravity whose amplitudes are defined as the evaluation of the coherent spin networks.Comment: 4 pages. Proceedings of Loops'11, Madrid. To appear in Journal of Physics: Conference Series (JPCS