Falling Short on Follow-Through: Assessing and Alleviating Implementation Gaps in U.S. Trafficking Policy for Foreign National Child and Youth Trafficking Survivors

This policy paper identifies four areas where policy does not reach child trafficking survivors, and provides recommendations on how the U.S. government can amend policies and practices to ensure it does not fall short on protecting foreign national child survivors of human trafficking

Investigating Effective Inspection of Object-Oriented Code

Since the development of software inspection over twenty-five years ago it has become established as an effective means of detecting defects. Inspections were originally developed at a time when the procedural paradigm was dominant but, with the Object- Oriented (OO) paradigm growing in influence and use, there now exists a lack of guidance on how to apply inspections to OO systems. Object-oriented and procedural languages differ not only in their syntax but also in a number of more profound ways - the encapsulation of data and associated functionality, the common use of inheritance, and the concepts of polymorphism and dynamic binding. These factors influence the way that modules (classes) are created in OO systems, which in turn influences the way that OO systems are structured and execute. Failure to take this into account may hinder the application of inspections to OO code. This thesis shows that the way in which the objectoriented paradigm distributes related functionality can have a serious impact on code inspection and, to address this problem, it develops and empirically evaluates three code reading techniques

Treatment of COPD: A matrix perspective

Fundamental physical properties, such as the intrinsic recoil of the lung, are governed by the extracellular matrix. The prototypical roles of the matrix proteins, collagen and elastin, in pulmonary fibrosis and emphysema have long been recognized, and much research effort has been devoted to understanding mechanisms of extracellular matrix synthesis and turnover in the lung. Yet, despite extensive knowledge of the biochemical properties of collagen and elastin, none of the present clinical strategies for treating COPD directly target the extracellular matrix. From a matrix perspective, therapeutic interventions that limit elastic fiber destruction and/or restore function to damaged alveolar units merit particular consideration as clinical strategies for treating the emphysema component of COPD. Effective treatment of the bronchiolar component of COPD requires a better understanding of the relationship between airway fibrosis and airflow obstruction. Translating basic knowledge of extracellular matrix biology into the clinical venue will be essential in the development of new approaches to COPD treatment