270 research outputs found
The optical response of Ba_{1-x}K_xBiO_3: Evidence for an unusual coupling mechanism of superconductivity?
We have analysed optical reflectivity data for Ba_{1-x}K_xBiO_3 in the
far-infrared region using Migdal-Eliashberg theory and found it inconsistent
with standard electron-phonon coupling: Whereas the superconducting state data
could be explained using moderate coupling, \lambda=0.7, the normal state
properties indicate \lambda \le 0.2. We have found that such behaviour could be
understood using a simple model consisting of weak standard electron-phonon
coupling plus weak coupling to an unspecified high energy excitation near 0.4
eV. This model is found to be in general agreement with the reflectivity data,
except for the predicted superconducting gap size. The additional high energy
excitation suggests that the dominant coupling mechanism in Ba_{1-x}K_xBiO_3 is
not standard electron-phonon.Comment: 5 pages REVTex, 5 figures, 32 refs, accepted for publication in Phys.
Rev.
Far-infrared transmission studies of c-axis oriented superconducting MgB2 thin film
We reported far-infrared transmission measurements on a c-axis oriented
superconducting MgB thin film in the frequency range of 30 250
cm. We found that these measurements were sensitive to values of
scattering rate and superconducting gap . By fitting the
experimental transmission spectra at 40 K and below, we obtained
(700 1000) cm and 42 cm. These two
quantities suggested that MgB belong to the dirty limit.Comment: submitted at May
First experimental evidence of one-dimensional plasma modes in superconducting thin wires
We have studied niobium superconducting thin wires deposited onto a
SrTiO substrate. By measuring the reflection coefficient of the wires,
resonances are observed in the superconducting state in the 130 MHz to 4 GHz
range. They are interpreted as standing wave resonances of one-dimensional
plasma modes propagating along the superconducting wire. The experimental
dispersion law, versus , presents a linear dependence over the
entire wave vector range. The modes are softened as the temperature increases
close the superconducting transition temperature. Very good agreement are
observed between our data and the dispersion relation predicted by Kulik and
Mooij and Sch\"on.Comment: Submitted to Physical review Letter
Technical note: Use of an atmospheric simulation chamber to investigate the effect of different engine conditions on unregulated VOC-IVOC diesel exhaust emissions
Diesel exhaust emissions were introduced into an atmospheric simulation chamber and measured using thermal desorption (TD) comprehensive two-dimensional gas chromatography coupled to a flame ionisation detector (GCβΓβGC-FID). An extensive set of measurements were performed to investigate the effect of different engine conditions (i.e. load, speed, driving scenarios) and emission control devices (with or without diesel oxidative catalyst, DOC) on the composition and abundance of unregulated exhaust gas emissions from a light-duty diesel engine, fuelled with ultra-low sulfur diesel (ULSD). A range of exhaust dilution ratios were investigated (rangeβ=β1:60 to 1:1158), simulating the chemical and physical transformations of the exhaust gas from near to downwind of an emission source. In total, 16 individual and 8 groups of compounds (aliphatics and single-ring aromatics) were measured in the exhaust gas ranging from volatile to intermediate volatility (VOC-IVOC), providing both detailed chemical speciation and groupings of compounds based on their structure and functionality. Measured VOC-IVOC emission rates displayed excellent reproducibility from replicate experiments using similar exhaust dilution ratios. However, at the extremes of the investigated exhaust dilution ratios (comparison of 1:60 and 1:1158), measured VOC-IVOC emission rates displayed some disagreement owing to poor reproducibility and highlighted the importance of replicate sample measurements. The investigated DOC was found to remove 43Β±10% (arithmetic meanΒ±experimental uncertainty) of the total speciated VOC-IVOC (βββSpVOC-IVOC) emissions. The compound class-dependant removal efficiencies for the investigated DOC were 39Β±12% and 83Β±3% for the aliphatics and single-ring aromatics, respectively. The DOC aliphatic removal efficiency generally decreased with increasing carbon chain length. The βββSpVOC-IVOC emission rates varied significantly with different engine conditions, ranging from 70 to 9268mgkgβ1 (milligrams of mass emitted per kilogram of fuel burnt). βββSpVOC-IVOC emission rates generally decreased with increasing engine load and temperature, and to a lesser degree, engine speed. The exhaust gas composition changed considerably as a result of two influencing factors: engine combustion and DOC hydrocarbon (HC) removal efficiency. Increased engine combustion efficiency resulted in a greater percentage contribution of the C7 to C12 n-alkanes to the βββSpVOC-IVOC emission rate. Conversely, increased DOC HC removal efficiency resulted in a greater percentage contribution of the C7 to C12 branched aliphatics to the βββSpVOC-IVOC emission rate. At low engine temperatures (β<β150Β°C, below the working temperature of the DOC), the contribution of n-alkanes in the exhaust gas increased with increasing combustion efficiency and may be important in urban environments, as n-alkanes are more efficient at producing secondary organic aerosol (SOA) than their branched counterparts. At very high engine temperatures (maximum applied engine speed and load, engine temperatureβ=β700Β°C), the n-alkane contribution increased by a factor of 1.6 times greater than that observed in the cold-start experiment (most similar to unburnt fuel) and may suggest liquid-fuel-based estimates of SOA yields may be inconsistent with exhaust SOA yields, particularly at high engine speeds and loads (i.e. high engine temperatures). Emission rates were found to be 65 times greater from a cold-start experiment than at maximum applied engine speed and load. To our knowledge, this is the first study which uses an atmospheric simulation chamber to separate the effects of the DOC and combustion efficiency on the exhaust gas composition
Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II.
Bone morphogenetic proteins (BMPs) are critically involved in early development and cell differentiation. In humans, dysfunction of the bone morphogenetic protein type II receptor (BMPR-II) is associated with pulmonary arterial hypertension (PAH) and neoplasia. The ability of Kaposi sarcoma-associated herpesvirus (KSHV), the etiologic agent of Kaposi sarcoma and primary effusion lymphoma, to down-regulate cell surface receptor expression is well documented. Here we show that KSHV infection reduces cell surface BMPR-II. We propose that this occurs through the expression of the viral lytic gene, K5, a ubiquitin E3 ligase. Ectopic expression of K5 leads to BMPR-II ubiquitination and lysosomal degradation with a consequent decrease in BMP signaling. The down-regulation by K5 is dependent on both its RING domain and a membrane-proximal lysine in the cytoplasmic domain of BMPR-II. We demonstrate that expression of BMPR-II protein is constitutively regulated by lysosomal degradation in vascular cells and provide preliminary evidence for the involvement of the mammalian E3 ligase, Itch, in the constitutive degradation of BMPR-II. Disruption of BMP signaling may therefore play a role in the pathobiology of diseases caused by KSHV infection, as well as KSHV-associated tumorigenesis and vascular disease
A self-consistent, multi-variate method for the determination of gas phase rate coefficients, applied to reactions of atmospheric VOCs and the hydroxyl radical
Gas-phase rate coefficients are fundamental to understanding atmospheric chemistry, yet experimental data are not available for the oxidation reactions of many of the thousands of volatile organic compounds (VOCs) observed in the troposphere. Here a new experimental method is reported for the simultaneous study of reactions between multiple different VOCs and OH, the most important daytime atmospheric radical oxidant. This technique is based upon established relative rate concepts but has the advantage of a much higher throughput of target VOCs. By evaluating multiple VOCs in each experiment, and through measurement of the depletion in each VOC after reaction with OH, the OH + VOC reaction rate coefficients can be derived. Results from experiments conducted under controlled laboratory conditions were in good agreement with the available literature for the reaction of nineteen VOCs, prepared in synthetic gas mixtures, with OH. This approach was used to determine a rate coefficient for the reaction of OH with 2,3-dimethylpent-1-ene for the first time; kβ=β5.7 (Β±0.3) Γ 10β11βcm3βmoleculeβ1βsβ1. In addition, a further seven VOCs had only two, or fewer, individual OH rate coefficient measurements available in the literature. The results from this work were in good agreement with those measurements. A similar dataset, at an elevated temperature of 323 (Β±10) K, was used to determine new OH rate coefficients for twelve aromatic, five alkane, five alkene and three monoterpene VOCβ+βOH reactions. In OH relative reactivity experiments that used ambient air at the University of York, a large number of different VOCs were observed, of which 23 were positively identified. 19 OH rate coefficients were derived from these ambient air samples, including ten reactions for which data was previously unavailable at the elevated reaction temperature of Tβ=β323 (Β±10) K
Cardiovascular disease in a cohort exposed to the 1940-45 Channel Islands occupation
BACKGROUND
To clarify the nature of the relationship between food deprivation/undernutrition during pre- and postnatal development and cardiovascular disease (CVD) in later life, this study examined the relationship between birth weight (as a marker of prenatal nutrition) and the incidence of hospital admissions for CVD from 1997β2005 amongst 873 Guernsey islanders (born in 1923β1937), 225 of whom had been exposed to food deprivation as children, adolescents or young adults (i.e. postnatal undernutrition) during the 1940β45 German occupation of the Channel Islands, and 648 of whom had left or been evacuated from the islands before the occupation began.
METHODS
Three sets of Cox regression models were used to investigate (A) the relationship between birth weight and CVD, (B) the relationship between postnatal exposure to the occupation and CVD and (C) any interaction between birth weight, postnatal exposure to the occupation and CVD. These models also tested for any interactions between birth weight and sex, and postnatal exposure to the occupation and parish of residence at birth (as a marker of parish residence during the occupation and related variation in the severity of food deprivation).
RESULTS
The first set of models (A) found no relationship between birth weight and CVD even after adjustment for potential confounders (hazard ratio (HR) per kg increase in birth weight: 1.12; 95% confidence intervals (CI): 0.70 β 1.78), and there was no significant interaction between birth weight and sex (p = 0.60). The second set of models (B) found a significant relationship between postnatal exposure to the occupation and CVD after adjustment for potential confounders (HR for exposed vs. unexposed group: 2.52; 95% CI: 1.54 β 4.13), as well as a significant interaction between postnatal exposure to the occupation and parish of residence at birth (p = 0.01), such that those born in urban parishes (where food deprivation was worst) had a greater HR for CVD than those born in rural parishes. The third model (C) found no interaction between birth weight and exposure to the occupation (p = 0.43).
CONCLUSION
These findings suggest that the levels of postnatal undernutrition experienced by children, adolescents and young adults exposed to food deprivation during the 1940β45 occupation of the Channel Islands were a more important determinant of CVD in later life than the levels of prenatal undernutrition experienced in utero prior to the occupatio
Search for Matter-Dependent Atmospheric Neutrino Oscillations in Super-Kamiokande
We consider muon neutrino to tau neutrino oscillations in the context of the
Mass Varying Neutrino (MaVaN) model, where the neutrino mass can vary depending
on the electron density along the flight path of the neutrino. Our analysis
assumes a mechanism with dependence only upon the electron density, hence
ordinary matter density, of the medium through which the neutrino travels.
Fully-contained, partially-contained and upward-going muon atmospheric neutrino
data from the Super--Kamiokande detector, taken from the entire SK--I period of
1489 live days, are compared to MaVaN model predictions. We find that, for the
case of 2-flavor oscillations, and for the specific models tested, oscillation
independent of electron density is favored over density dependence. Assuming
maximal mixing, the best-fit case and the density-independent case do not
differ significantly.Comment: 6 pages, 1 figur
Solar neutrino measurements in Super-Kamiokande-II
The results of the second phase of the Super-Kamiokande solar neutrino
measurement are presented and compared to the first phase. The solar neutrino
flux spectrum and time-variation as well as oscillation results are
statistically consistent with the first phase and do not show spectral
distortion. The time-dependent flux measurement of the combined first and
second phases coincides with the full period of solar cycle 23 and shows no
correlation with solar activity. The measured boron 8 total flux is 2.38
+/-0.05(stat.) +0.16-0.15(sys.) X 10^6 cm^-2 sec^-1 and the day-night
difference is found to be -6.3 +/-4.2(stat.) +/-3.7(sys.) %. There is no
evidence of systematic tendencies between the first and second phases
Understanding in situ ozone production in the summertime through radical observations and modelling studies during the Clean air for London project (ClearfLo)
Measurements of OH, HO2, RO2i (alkene and aromatic-related RO2) and total RO2 radicals taken during the ClearfLo campaign in central London in the summer of 2012 are presented. A photostationary steady-state calculation of OH which considered measured OH reactivity as the OH sink term and the measured OH sources (of which HO2+ NO reaction and HONO photolysis dominated) compared well with the observed levels of OH. Comparison with calculations from a detailed box model utilising the Master Chemical Mechanism v3.2, however, highlighted a substantial discrepancy between radical observations under lower NOx conditions ([NO] 3 ppbv) the box model increasingly underpredicted total [RO2]. The modelled and observed HO2 were in agreement, however, under elevated NO concentrations ranging from 7 to 15 ppbv. The model uncertainty under low NO conditions leads to more ozone production predicted using modelled peroxy radical concentrations ( β 3 ppbv h-1) versus ozone production from peroxy radicals measured ( β 1 ppbv h-1). Conversely, ozone production derived from the predicted peroxy radicals is up to an order of magnitude lower than from the observed peroxy radicals as [NO] increases beyond 7 ppbv due to the model underprediction of RO2 under these conditions
- β¦