11,297 research outputs found

    Turning up the lights - fabrication of brighter SERRS nanotags

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    Brighter SERRS nanotags ideal for improved SERRS imaging were prepared by the controlled addition of electrolyte producing a dimer enriched solution, which was incubated with a Raman reporter before being stabilised by a polyethylene glycol (PEG) shell

    Eudaimonism about Virtue and Qualified Agent Right Action: Some Prospects for Environmental Virtue Ethics

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    In this thesis, I aim to show that virtue oriented approaches to environmental ethics are in a position to provide satisfying answers to two central ethical questions: “What kind of person should I be?”, and “What should I do?” I argue that two such approaches – Rosalind Hursthouse’s environmental virtue ethics and Philip Cafaro’s account of environmental vice – provide insights about how we ought to be with regard to the environment, in terms of character and attitudes. I then defend Hursthouse’s account of right action against several objections. First, I respond to the worry that a shortage of environmental exemplars might count against Hursthouse, by showing that non-virtuous agents can conceive of what to do by seeking to avoid acting from environmental vices. Second, I respond the worry that her account of right action fails to generate the right result for non-virtuous agents in some cases, by showing that such cases can be accounted for by appeal to the distinction between action guidance and action assessment. Third, I consider the worry that her theory will fail to provide concrete action guidance. Theories which seek to provide concrete action guidance in all contexts face serious problems of their own, I respond. Further, I maintain that Hursthouse is not ruled out from providing the sort of action guidance her critics are interested in

    The Effect of Adrenal Steroid Hormones on the Protein Content of Tumorous Livers

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    Protein is basic to the structure and function of protoplasm. Enzyme systems which regulate the rate of cellular reactions are primarily composed of protein and many of these enzymatic systems influence the metabolism of less specialized proteins that form the major structural material of protoplasm. It is believed that experimental procedures which modify protein composition of cells may also influence the activity of intra-cellular enzymes. In experimental live cancer, it has been shown that the activities of a number of oxidative enzymes are modified as the carcinogenic process proceeds (Richmond, 1955, p.38). Furthermore, it has been demonstrated that endocrine function influences carcinogenic processes. Moon, et. al. (1951, p. 539) reported that long-term administration of growth hormone to hypophysectiomized rats did not produce the numerous neoplasms that developed in control rats. Hormones of the adrenal cortex are intimately involved in the regulation of protein metabolism, and Umbriet (1951, p 574) showed that cortisone influences enzyme systems that aid in the degradation of cellular protein. Such studies indicate that more work is needed on the effects of adrenal hormones on protein composition and activity during carcinogenesis. Symeonidis, et. al. (1954, p 811) have reported that certain modifications of adrenal function inhibit liver tumor formations that occurs after the feeding of the azo dye para-dimethylaminoazobenzene (DAB). The present study was undertaken to determine whether modifications in adrenal function would affect the protein composition of the liver of rats fed potent azo dye 3\u27-methly-4-dimethylaminoazobenzene (3\u27-Me-DAB). Attempts were made to correlate these findings with changes in enzyme activity that have been reported by other

    Selling the modern day tribe: The commodification of rave culture

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    This thesis examines youth and rave culture from the late 1980s to the present. It considers the history as well as the global and local impact of rave. I provide a visual ethnographic study from 1999-2014, based on my work as a commercial photographer of the Perth, Western Australian scene. While critically reflecting on existing subcultural research this thesis adds another dimension – the effect that global corporations have had in reshaping subcultural practices, specifically the commodification of rave culture in the form of the contemporary electronic dance festival. The research incorporates both qualitative and quantitative data to interrogate media coverage on rave culture as well as interviews and first hand experience within the rave scene. I analyse mainstream print and electronic media reporting of rave as a deviant youth subcultural practice linked to the use of the drug ecstasy. I consider the effect this had on rave and it’s rebranding to become known in contemporary times as EDM (electronic dance music). As a result I examine how rave has shifted from a youth subcultural activity to being not only mainstream and commercial, but also owned and controlled by global corporations. My discussion of the conventions of festival/music scenes will demonstrate how rave, which once operated outside ‘acceptable’ boundaries, has become a part of the conventional norm. A unique aspect of this thesis is the inclusion and analysis of my photographs taken over a 15 year period that document the changes that occurred as rave transitioned from a subversive underground scene to corporate run multimillion dollar events. The photographs are also compiled into an accompanying monograph. The monograph allows for an immersive visual experience of non-staged event images and predetermined studio and location photographs. The book offers what words alone cannot fully engage with – a representation of what was and remains a highly visual scene, based on fashion, performance and settings

    Higher Order QCD Corrections to Electroweak Boson Production at Colliders

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    In this thesis we consider the Next-to-Next-to-Leading Order (NNLO) corrections to single charged electroweak boson production with associated QCD radiation in hadron-hadron collisions, calculated using the antenna subtraction method to regulate infrared (IR) divergences. Results are presented alongside the neutral current case for the inclusive transverse momentum spectrum and subsequent ratios both with and without the addition of state-of-the-art resummation results. In the former case a comparison to CMS data is also provided. We also discuss the phenomenological implications of the results when one or more jets are reconstructed from the QCD radiation. Particular attention is given to the impact on valence quark content of Parton Distribution Functions (PDFs) through a comparison with experimental results from the ATLAS, CMS and LHCb collaborations. We then discuss the use of fixed-order QCD predictions for inclusive Drell-Yan production in the context of an effective Weinberg angle extraction using triple-differential data taken by the ATLAS collaboration at s=8 TeV\sqrt{s}=8~\mathrm{TeV}, using the kinematics to extend the predictions to Next-to-Next-to-Next-to-Leading Order (N3^3LO) for certain parts of the measurement. Finally, using the antenna subtraction method we derive the NNLO QCD corrections to di-jet production in charged-current Deep Inelastic Scattering (DIS), allowing the first comparison to ZEUS data at this order. These results are then combined with inclusive structure functions using the method of projection-to-Born (p2B) in order to derive the first exclusive fiducial predictions for single jet inclusive production in charged-current DIS to N3^3LO. A comparison to data is performed, where we observe reasonable agreement with the experimental results from ZEUS

    CMOS-compatible high-voltage transistors

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