The analysis of solar models: Neutrinos and oscillations

Tests of solar neutrino flux and solar oscillation frequencies were used to assess standard stellar structure theory. Standard and non-standard solar models are enumerated and discussed. The field of solar seismology, wherein the solar interior is studied from the measurement of solar oscillations, is introduced

Electromagnetic processing – from AC to DC Field - A way for process improvement and innovation

International audienceTechnology of Electromagnetic processing of Materials (EPM) is relatively well known and mature. This knowledge gives the possibility to improve such processes and to integrate them in specific application (aeronautics, automotive sector, metallurgy...) at industrial scale. Thanks to a transverse and multiphysics approach which combined fluid dynamics, heat transfer, process metallurgy, solidification…, it is possible to know how to design new innovative processes with the integration of new design of electromagnetic system. An association of more complex EM configurations can be achieved: combination of AC and DC field, or two AC field… Future development of EPM technologies are in agreement with energy savings and CO 2 reduction demand. In metallurgy industry, the integration of EPM technologies is more basically associated with productivity improvement, maintenance reduction and also safety consideration. EM processing can be classified by type of magnetic field involved: from AC to DC field. The choice depends on the desired action on the electro conductive materials. These processes are suitable for heating, melting, flow and shape control, solidification control (stirring, pumping)…but for each application a specific configuration needs to be defined, selected and optimized. This paper gives some examples of EPM technologies applications for the development of new industrial process and main challenge to succeed in order to be relevant: (i) cold crucible technology or levitation, (ii) electromagnetic pump and (iii) DC electromagnetic brake. A combined approach by using numerical multiphysics modeling and experimental validation is used in order to give some guidelines for process improvement, or new electromagnetic design: feasibility and potentiality for integration at industrial scale

X-ray enabled MOCASSIN: a 3D code for photoionized media

We present a new version of the fully 3D photoionization and dust radiative transfer code, MOCASSIN, that uses a Monte Carlo approach for the transfer of radiation. The X-ray enabled MOCASSIN allows a fully geometry independent description of low-density gaseous environments strongly photoionized by a radiation field extending from radio to gamma rays. The code has been thoroughly benchmarked against other established codes routinely used in the literature, using simple plane parallel models designed to test performance under standard conditions. We show the results of our benchmarking exercise and discuss applicability and limitations of the new code, which should be of guidance for future astrophysical studies with MOCASSIN.Comment: Accepted for publication in ApJS 9 pages, 5 figure

The Origin of Fe II Emission in AGN

We used a very large set of models of broad emission line (BEL) clouds in AGN to investigate the formation of the observed Fe II emission lines. We show that photoionized BEL clouds cannot produce both the observed shape and observed equivalent width of the 2200-2800A Fe II UV bump unless there is considerable velocity structure corresponding to a microturbulent velocity parameter v_turb > 100 km/s for the LOC models used here. This could be either microturbulence in gas that is confined by some phenomenon such as MHD waves, or a velocity shear such as in the various models of winds flowing off the surfaces of accretion disks. The alternative way that we can find to simultaneously match both the observed shape and equivalent width of the Fe II UV bump is for the Fe II emission to be the result of collisional excitation in a warm, dense gas. Such gas would emit very few lines other than Fe II. However, since the collisionally excited gas would constitute yet another component in an already complicated picture of the BELR, we prefer the model involving turbulence. In either model, the strength of Fe II emission relative to the emission lines of other ions such as Mg II depends as much on other parameters (either v_turb or the surface area of the collisionally excited gas) as it does on the iron abundance. Therefore, the measurement of the iron abundance from the FeII emission in quasars becomes a more difficult problem.Comment: 23 pages. Accepted by Ap

Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model.

One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge. The complex, dynamic, inhibitory microenvironment postinjury, which is characterized by proinflammatory signaling from invading leukocytes and lack of sufficient factors that promote axonal survival and elongation, limits regeneration. Herein, we investigated the delivery of polycistronic vectors, which have the potential to coexpress factors that target distinct barriers to regeneration, from a multiple channel poly(lactide-co-glycolide) (PLG) bridge to enhance spinal cord regeneration. In this study, we investigated polycistronic delivery of IL-10 that targets proinflammatory signaling, and NT-3 that targets axonal survival and elongation. A significant increase was observed in the density of regenerative macrophages for IL-10+NT-3 condition relative to conditions without IL-10. Furthermore, combined delivery of IL-10+NT-3 produced a significant increase of axonal density and notably myelinated axons compared with all other conditions. A significant increase in functional recovery was observed for IL-10+NT-3 delivery at 12 weeks postinjury that was positively correlated to oligodendrocyte myelinated axon density, suggesting oligodendrocyte-mediated myelination as an important target to improve functional recovery. These results further support the use of multiple channel PLG bridges as a growth supportive substrate and platform to deliver bioactive agents to modulate the SCI microenvironment and promote regeneration and functional recovery. Impact statement Spinal cord injury (SCI) results in a complex microenvironment that contains multiple barriers to regeneration and functional recovery. Multiple factors are necessary to address these barriers to regeneration, and polycistronic lentiviral gene therapy represents a strategy to locally express multiple factors simultaneously. A bicistronic vector encoding IL-10 and NT-3 was delivered from a poly(lactide-co-glycolide) bridge, which provides structural support that guides regeneration, resulting in increased axonal growth, myelination, and subsequent functional recovery. These results demonstrate the opportunity of targeting multiple barriers to SCI regeneration for additive effects

PLG Bridge Implantation in Chronic SCI Promotes Axonal Elongation and Myelination.

Spinal cord injury (SCI) is a devastating condition that may cause permanent functional loss below the level of injury, including paralysis and loss of bladder, bowel, and sexual function. Patients are rarely treated immediately, and this delay is associated with tissue loss and scar formation that can make regeneration at chronic time points more challenging. Herein, we investigated regeneration using a poly(lactide-co-glycolide) multichannel bridge implanted into a chronic SCI following surgical resection of necrotic tissue. We characterized the dynamic injury response and noted that scar formation decreased at 4 and 8 weeks postinjury (wpi), yet macrophage infiltration increased between 4 and 8 wpi. Subsequently, the scar tissue was resected and bridges were implanted at 4 and 8 wpi. We observed robust axon growth into the bridge and remyelination at 6 months after initial injury. Axon densities were increased for 8 week bridge implantation relative to 4 week bridge implantation, whereas greater myelination, particularly by Schwann cells, was observed with 4 week bridge implantation. The process of bridge implantation did not significantly decrease the postinjury function. Collectively, this chronic model follows the pathophysiology of human SCI, and bridge implantation allows for clear demarcation of the regenerated tissue. These data demonstrate that bridge implantation into chronic SCI supports regeneration and provides a platform to investigate strategies to buttress and expand regeneration of neural tissue at chronic time points

The Circumstellar Disk of HD 141569 Imaged with NICMOS

Coronagraphic imaging with the Near Infrared Camera and Multi Object Spectrometer on the Hubble Space Telescope reveals a large, ~400 AU (4'') radius, circumstellar disk around the Herbig Ae/Be star HD 141569. A reflected light image at 1.1 micron shows the disk oriented at a position angle of 356 +/- 5 deg and inclined to our line of sight by 51 +/- 3 deg; the intrinsic scattering function of the dust in the disk makes the side inclined toward us, the eastern side, brighter. The disk flux density peaks 185 AU (1.''85) from the star and falls off to both larger and smaller radii. A region of depleted material, or a gap, in the disk is centered 250 AU from the star. The dynamical effect of one or more planets may be necessary to explain this morphology.Comment: 4 pages, LaTeX with emulateapj.sty and epsfig.sty, 4 postscript figures, Accepted to ApJ Letter

Técnica “Buddy wire” en implantación de válvula aórtica transcatéter con válvula expandible con balón: una opción de rescate en casos con implantación directa de válvula (sin predilatación)

Abstract not availableRicardo Allende, Rishi Puri, Éric Dumont, María del Trigo, Omar Abdul-Jawad Altisent, Josep Rodés-Caba

Aperiodic Ising model on the Bethe lattice: Exact results

We consider the Ising model on the Bethe lattice with aperiodic modulation of the couplings, which has been studied numerically in Phys. Rev. E 77, 041113 (2008). Here we present a relevance-irrelevance criterion and solve the critical behavior exactly for marginal aperiodic sequences. We present analytical formulae for the continuously varying critical exponents and discuss a relationship with the (surface) critical behavior of the aperiodic quantum Ising chain.Comment: 7 pages, 3 figures, minor correction